Millisecond-timescale, genetically targeted optical control of neural activity ES Boyden, F Zhang, E Bamberg, G Nagel, K Deisseroth Nature neuroscience 8 (9), 1263-1268, 2005 | 5795 | 2005 |
Parvalbumin neurons and gamma rhythms enhance cortical circuit performance VS Sohal, F Zhang, O Yizhar, K Deisseroth Nature 459 (7247), 698-702, 2009 | 2852 | 2009 |
Driving fast-spiking cells induces gamma rhythm and controls sensory responses JA Cardin, M Carlén, K Meletis, U Knoblich, F Zhang, K Deisseroth, ... Nature 459 (7247), 663-667, 2009 | 2836 | 2009 |
Neocortical excitation/inhibition balance in information processing and social dysfunction O Yizhar, LE Fenno, M Prigge, F Schneider, TJ Davidson, DJ O’shea, ... Nature 477 (7363), 171-178, 2011 | 2558 | 2011 |
Optogenetics K Deisseroth Nature methods 8 (1), 26-29, 2011 | 2391 | 2011 |
Structural and molecular interrogation of intact biological systems K Chung, J Wallace, SY Kim, S Kalyanasundaram, AS Andalman, ... Nature 497 (7449), 332-337, 2013 | 2205 | 2013 |
Optogenetics in neural systems O Yizhar, LE Fenno, TJ Davidson, M Mogri, K Deisseroth Neuron 71 (1), 9-34, 2011 | 2198 | 2011 |
Multimodal fast optical interrogation of neural circuitry F Zhang, LP Wang, M Brauner, JF Liewald, K Kay, N Watzke, PG Wood, ... Nature 446 (7136), 633-639, 2007 | 2149 | 2007 |
The development and application of optogenetics L Fenno, O Yizhar, K Deisseroth Annual review of neuroscience 34 (1), 389-412, 2011 | 2146 | 2011 |
Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry AV Kravitz, BS Freeze, PRL Parker, K Kay, MT Thwin, K Deisseroth, ... Nature 466 (7306), 622-626, 2010 | 1999 | 2010 |
Optogenetic stimulation of a hippocampal engram activates fear memory recall X Liu, S Ramirez, PT Pang, CB Puryear, A Govindarajan, K Deisseroth, ... Nature 484 (7394), 381-385, 2012 | 1760 | 2012 |
Optical deconstruction of parkinsonian neural circuitry V Gradinaru, M Mogri, KR Thompson, JM Henderson, K Deisseroth science 324 (5925), 354-359, 2009 | 1759 | 2009 |
Neural substrates of awakening probed with optogenetic control of hypocretin neurons AR Adamantidis, F Zhang, AM Aravanis, K Deisseroth, L De Lecea Nature 450 (7168), 420-424, 2007 | 1536 | 2007 |
Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning HC Tsai, F Zhang, A Adamantidis, GD Stuber, A Bonci, L De Lecea, ... Science 324 (5930), 1080-1084, 2009 | 1502 | 2009 |
Amygdala circuitry mediating reversible and bidirectional control of anxiety KM Tye, R Prakash, SY Kim, LE Fenno, L Grosenick, H Zarabi, ... Nature 471 (7338), 358-362, 2011 | 1412 | 2011 |
CREB phosphorylation and dephosphorylation: a Ca2+-and stimulus duration–dependent switch for hippocampal gene expression H Bito, K Deisseroth, RW Tsien Cell 87 (7), 1203-1214, 1996 | 1403 | 1996 |
Input-specific control of reward and aversion in the ventral tegmental area S Lammel, BK Lim, C Ran, KW Huang, MJ Betley, KM Tye, K Deisseroth, ... Nature 491 (7423), 212-217, 2012 | 1369 | 2012 |
Natural neural projection dynamics underlying social behavior LA Gunaydin, L Grosenick, JC Finkelstein, IV Kauvar, LE Fenno, ... Cell 157 (7), 1535-1551, 2014 | 1337 | 2014 |
Optogenetics: 10 years of microbial opsins in neuroscience K Deisseroth Nature neuroscience 18 (9), 1213-1225, 2015 | 1306 | 2015 |
Molecular and cellular approaches for diversifying and extending optogenetics V Gradinaru, F Zhang, C Ramakrishnan, J Mattis, R Prakash, I Diester, ... Cell 141 (1), 154-165, 2010 | 1225 | 2010 |