Recent advances of the Povarov reaction in medicinal chemistry O Ghashghaei, C Masdeu, C Alonso, F Palacios, R Lavilla Drug Discovery Today: Technologies 29, 71-79, 2018 | 93 | 2018 |
Highly enantioselective conjugate additions of aldehydes to vinyl sulfones A Landa, M Maestro, C Masdeu, A Puente, S Vera, M Oiarbide, C Palomo Chemistry–A European Journal 15 (7), 1562-1565, 2009 | 93 | 2009 |
Formation of γ-Oxoacids and 1H-Pyrrol-2(5H)-ones from α,β-Unsaturated Ketones and Ethyl Nitroacetate M Aginagalde, T Bello, C Masdeu, Y Vara, A Arrieta, FP Cossio The Journal of Organic Chemistry 75 (21), 7435-7438, 2010 | 49 | 2010 |
Double insertion of isocyanides into dihydropyridines: Direct access to substituted benzimidazolium salts C Masdeu, E Gomez, NAO Williams, R Lavilla Angewandte Chemie 119 (17), 3103-3106, 2007 | 44 | 2007 |
Isocyanide addition to pyridinium salts. Efficient entry into substituted nicotinonitrile derivatives NAO Williams, C Masdeu, JL Diaz, R Lavilla Organic Letters 8 (25), 5789-5792, 2006 | 35 | 2006 |
Introduction of Heteroatom‐Based Substituents into 1, 4‐Dihydropyridines by Means of a Halogen‐Mediated, Oxidative Protocol: Diamination, Sulfonylation, Sulfinylation, Bis … R Lavilla, R Kumar, O Coll, C Masdeu, A Spada, J Bosch, E Espinosa, ... Chemistry–A European Journal 6 (10), 1763-1772, 2000 | 28 | 2000 |
Azole additions upon azinium salts R Lavilla, T Gotsens, M Guerrero, C Masdeu, MC Santano, C Minguillón, ... Tetrahedron 53 (40), 13959-13968, 1997 | 28 | 1997 |
Benzimidazolium salts as small, nonpeptidic and BBB‐permeable human prolyl oligopeptidase inhibitors T Tarrago, C Masdeu, E Gomez, N Isambert, R Lavilla, E Giralt ChemMedChem: Chemistry Enabling Drug Discovery 3 (10), 1558-1565, 2008 | 25 | 2008 |
Straightforward α-carbamoylation of NADH-like dihydropyridines and enol ethers C Masdeu, JL Dı́az, M Miguel, O Jiménez, R Lavilla Tetrahedron letters 45 (42), 7907-7909, 2004 | 25 | 2004 |
“Nonbiomimetic” Oxidations of Dihydropyridines R Lavilla, X Barón, O Coll, F Gullón, C Masdeu, J Bosch The Journal of Organic Chemistry 63 (26), 10001-10005, 1998 | 24 | 1998 |
A patent review of topoisomerase I inhibitors (2016–present) A Selas, E Martin-Encinas, M Fuertes, C Masdeu, G Rubiales, F Palacios, ... Expert Opinion on Therapeutic Patents 31 (6), 473-508, 2021 | 23 | 2021 |
Hydro‐, Halo‐and Seleno‐Carbamoylation of Cyclic Enol Ethers and Dihydropyridines: New Mechanistic Pathways for Passerini‐and Ugi‐type Multicomponent Reactions C Masdeu, E Gomez, NA Williams, R Lavilla QSAR & Combinatorial Science 25 (5‐6), 465-473, 2006 | 19 | 2006 |
Multicomponent access to functionalized mesoionic structures based on TFAA activation of isocyanides: Novel domino reactions MJ Arévalo, N Kielland, C Masdeu, M Miguel, N Isambert, R Lavilla European Journal of Organic Chemistry 2009 (5), 617-625, 2009 | 18 | 2009 |
Fused 1, 5-naphthyridines: synthetic tools and applications C Masdeu, M Fuertes, E Martin-Encinas, A Selas, G Rubiales, F Palacios, ... Molecules 25 (15), 3508, 2020 | 17 | 2020 |
In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma M Pérez-Salvia, E Aldaba, Y Vara, M Fabre, C Ferrer, C Masdeu, A Zubia, ... Haematologica 103 (11), e537, 2018 | 16 | 2018 |
Copper (II)-promoted oxidation/[3+ 2] cycloaddition/aromatization cascade: efficient synthesis of tetrasubstituted NH-pyrrole from chalcones and iminodiacetates Z Lin, C Li, Z Zhou, S Xue, J Gao, Q Ye, Y Li Synlett 30 (12), 1442-1446, 2019 | 15 | 2019 |
Synthetic strategies, reactivity and applications of 1, 5-naphthyridines M Fuertes, C Masdeu, E Martin-Encinas, A Selas, G Rubiales, F Palacios, ... Molecules 25 (14), 3252, 2020 | 12 | 2020 |
Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium SaltsFNR HREF=" nss"> FN ID=" nss"> This work was supported by DGICYT (Spain … C Masdeu, E Gomez, NAO Williams, R Lavilla Angewandte Chemie-German Edition 119 (17), 3103-3106, 2007 | 12 | 2007 |
Vicinal diamination of 1, 4-dihydropyridines R Lavilla, R Kumar, O Coll, C Masdeu, J Bosch Chemical Communications, 2715-2716, 1998 | 12 | 1998 |
Puente, S. Vera, M. Oiarbide, C. Palomo A Landa, M Maestro, C Masdeu Chem. Eur. J 15, 1562, 2009 | 11 | 2009 |