Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans CT Murphy, SA McCarroll, CI Bargmann, A Fraser, RS Kamath, J Ahringer, ... Nature 424 (6946), 277-283, 2003 | 2431 | 2003 |
Regulation of aging and age-related disease by DAF-16 and heat-shock factor AL Hsu, CT Murphy, C Kenyon Science 300 (5622), 1142-1145, 2003 | 1647 | 2003 |
Insulin/insulin-like growth factor signaling in C. elegans CT Murphy, PJ Hu WormBook: The Online Review of C. elegans Biology [Internet], 2018 | 559 | 2018 |
Comparing genomic expression patterns across species identifies shared transcriptional profile in aging SA McCarroll, CT Murphy, S Zou, SD Pletcher, CS Chin, YN Jan, ... Nature genetics 36 (2), 197-204, 2004 | 510 | 2004 |
Condition‐adapted stress and longevity gene regulation by Caenorhabditis elegans SKN‐1/Nrf RP Oliveira, JP Abate, K Dilks, J Landis, J Ashraf, CT Murphy, ... Aging cell 8 (5), 524-541, 2009 | 359 | 2009 |
Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression SJ Lee, CT Murphy, C Kenyon Cell metabolism 10 (5), 379-391, 2009 | 357 | 2009 |
PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity RG Tepper, J Ashraf, R Kaletsky, G Kleemann, CT Murphy, ... Cell 154 (3), 676-690, 2013 | 302 | 2013 |
Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity CY Ewald, JN Landis, JP Abate, CT Murphy, TK Blackwell Nature 519 (7541), 97-101, 2015 | 271 | 2015 |
Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age AL Kauffman, JM Ashraf, MR Corces-Zimmerman, JN Landis, CT Murphy PLoS biology 8 (5), e1000372, 2010 | 263 | 2010 |
TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance S Luo, GA Kleemann, JM Ashraf, WM Shaw, CT Murphy Cell 143 (2), 299-312, 2010 | 255 | 2010 |
The C. elegans TGF-β dauer pathway regulates longevity via insulin signaling WM Shaw, S Luo, J Landis, J Ashraf, CT Murphy Current biology 17 (19), 1635-1645, 2007 | 245 | 2007 |
The search for DAF-16/FOXO transcriptional targets: approaches and discoveries CT Murphy Experimental gerontology 41 (10), 910-921, 2006 | 216 | 2006 |
The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators R Kaletsky, V Lakhina, R Arey, A Williams, J Landis, J Ashraf, CT Murphy Nature 529 (7584), 92-96, 2016 | 210 | 2016 |
Piwi/PRG-1 argonaute and TGF-β mediate transgenerational learned pathogenic avoidance RS Moore, R Kaletsky, CT Murphy Cell 177 (7), 1827-1841. e12, 2019 | 206 | 2019 |
The cell biology of aging R DiLoreto, CT Murphy Molecular biology of the cell 26 (25), 4524-4531, 2015 | 204 | 2015 |
Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans CT Murphy, SJ Lee, C Kenyon Proceedings of the National Academy of Sciences 104 (48), 19046-19050, 2007 | 199 | 2007 |
C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation JH Hahm, S Kim, R DiLoreto, C Shi, SJV Lee, CT Murphy, HG Nam Nature communications 6 (1), 8919, 2015 | 193 | 2015 |
Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression R Kaletsky, V Yao, A Williams, AM Runnels, A Tadych, S Zhou, ... PLoS genetics 14 (8), e1007559, 2018 | 146 | 2018 |
EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan G Liu, J Rogers, CT Murphy, C Rongo The EMBO journal 30 (15), 2990-3003, 2011 | 135 | 2011 |
Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs V Lakhina, RN Arey, R Kaletsky, A Kauffman, G Stein, W Keyes, D Xu, ... Neuron 85 (2), 330-345, 2015 | 133 | 2015 |