| Novel therapeutic approaches against acetaminophen-induced liver injury and acute liver failure H Jaeschke, JY Akakpo, DS Umbaugh, A Ramachandran Toxicological Sciences 174 (2), 159-167, 2020 | 128 | 2020 |
| Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls H Jaeschke, OB Adelusi, JY Akakpo, NT Nguyen, G Sanchez-Guerrero, ... Acta Pharmaceutica Sinica B 11 (12), 3740-3755, 2021 | 56 | 2021 |
| Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice NT Nguyen, K Du, JY Akakpo, DS Umbaugh, H Jaeschke, ... Toxicology letters 338, 21-31, 2021 | 42 | 2021 |
| Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice NT Nguyen, DS Umbaugh, G Sanchez-Guerrero, A Ramachandran, ... Archives of toxicology, 1-16, 2022 | 35 | 2022 |
| Mitochondrial membrane potential drives early change in mitochondrial morphology after acetaminophen exposure DS Umbaugh, NT Nguyen, H Jaeschke, A Ramachandran Toxicological Sciences 180 (1), 186-195, 2021 | 24 | 2021 |
| Somatostatin receptor subtype-4 regulates mRNA expression of amyloid-beta degrading enzymes and microglia mediators of phagocytosis in brains of 3xTg-AD mice K Sandoval, D Umbaugh, A House, A Crider, K Witt Neurochemical research 44, 2670-2680, 2019 | 24 | 2019 |
| Spatial reconstruction of the early hepatic transcriptomic landscape after an acetaminophen overdose using single-cell RNA-sequencing DS Umbaugh, A Ramachandran, H Jaeschke Toxicological Sciences 182 (2), 327-345, 2021 | 23 | 2021 |
| Regulation of liver regeneration by hepatocyte O-GlcNAcylation in mice DR Robarts, SR McGreal, DS Umbaugh, WS Parkes, M Kotulkar, ... Cellular and molecular gastroenterology and hepatology 13 (5), 1510-1529, 2022 | 21 | 2022 |
| Biomarkers of drug-induced liver injury: A mechanistic perspective through acetaminophen hepatotoxicity DS Umbaugh, H Jaeschke Expert review of gastroenterology & hepatology 15 (4), 363-375, 2021 | 21 | 2021 |
| Mitochondrial dynamics in drug-induced liver injury A Ramachandran, DS Umbaugh, H Jaeschke Livers 1 (3), 102-115, 2021 | 19 | 2021 |
| Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice NT Nguyen, DS Umbaugh, S Smith, OB Adelusi, G Sanchez-Guerrero, ... Archives of Toxicology 97 (5), 1397-1412, 2023 | 17 | 2023 |
| Extracellular vesicles: Roles and applications in drug-induced liver injury DS Umbaugh, H Jaeschke Advances in clinical chemistry 102, 63-125, 2021 | 11 | 2021 |
| Mfsd2a and Glut1 brain nutrient transporters expression increase with 32-week low and high lard compared with fish-oil dietary treatment in C57Bl/6 mice KE Sandoval, JS Wooten, MP Harris, ML Schaller, DS Umbaugh, KA Witt Current developments in nutrition 2 (10), nzy065, 2018 | 11 | 2018 |
| Thermography based prescreening software tool for veterinary clinics R Dahal, SE Umbaugh, D Mishra, N Lama, M Alvandipour, D Umbaugh, ... Thermosense: Thermal Infrared Applications XXXIX 10214, 335-342, 2017 | 7 | 2017 |
| Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblasts DS Umbaugh, RP Soder, NT Nguyen, O Adelusi, DR Robarts, ... Archives of toxicology 96 (12), 3315-3329, 2022 | 6 | 2022 |
| The effects of voluntary wheel running during weight-loss on biomarkers of hepatic lipid metabolism and inflammation in C57Bl/6J mice JS Wooten, KE Poole, MP Harris, BL Guilford, ML Schaller, D Umbaugh, ... Current Research in Physiology 5, 63-72, 2022 | 4 | 2022 |
| The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure DS Umbaugh, NT Nguyen, SC Curry, JA Rule, WM Lee, A Ramachandran, ... Hepatology, 10.1097, 2023 | 3 | 2023 |
| Role of pyroptosis in acetaminophen-induced hepatotoxicity H Jaeschke, DS Umbaugh, A Ramachandran Livers 2 (4), 425-435, 2022 | 3 | 2022 |
| Recovered hepatocytes promote macrophage apoptosis through CXCR4 after acetaminophen-induced liver injury in mice NT Nguyen, DS Umbaugh, EL Huang, OB Adelusi, G Sanchez Guerrero, ... Toxicological Sciences 188 (2), 248-260, 2022 | 3 | 2022 |
| Hepatocyte Senescence is Initiated through a Klf6-p21 Mechanism which mediates the Production of Cxcl14, a Novel Prognostic Biomarker of Acute Liver Failure D Umbaugh, N Nguyen, GS Guerrero, C Villanueva, B Hagenbuch, ... Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | 2 | 2023 |
Hartmut JaeschkeUniversity Distinguished Professor and Chair, University of Kansas Medical Center在 kumc.edu 的电子邮件经过验证
Hartmut JaeschkeUniversity Distinguished Professor and Chair, University of Kansas Medical Center在 kumc.edu 的电子邮件经过验证