Intra-tumoral tertiary lymphoid structures are associated with a low risk of early recurrence of hepatocellular carcinoma J Calderaro, F Petitprez, E Becht, A Laurent, TZ Hirsch, B Rousseau, ... Journal of hepatology 70 (1), 58-65, 2019 | 273 | 2019 |
Clinical impact of genomic diversity from early to advanced hepatocellular carcinoma JC Nault, Y Martin, S Caruso, TZ Hirsch, Q Bayard, J Calderaro, C Charpy, ... Hepatology 71 (1), 164-182, 2020 | 157 | 2020 |
Hepatitis B virus integrations promote local and distant oncogenic driver alterations in hepatocellular carcinoma C Péneau, S Imbeaud, T La Bella, TZ Hirsch, S Caruso, J Calderaro, ... Gut 71 (3), 616-626, 2022 | 132 | 2022 |
Adeno-associated virus in the liver: natural history and consequences in tumour development T La Bella, S Imbeaud, C Peneau, I Mami, S Datta, Q Bayard, S Caruso, ... Gut 69 (4), 737-747, 2020 | 107 | 2020 |
Telomere length is key to hepatocellular carcinoma diversity and telomerase addiction is an actionable therapeutic target M Ningarhari, S Caruso, TZ Hirsch, Q Bayard, A Franconi, AL Védie, ... Journal of Hepatology 74 (5), 1155-1166, 2021 | 73 | 2021 |
Palimpsest: an R package for studying mutational and structural variant signatures along clonal evolution in cancer J Shinde, Q Bayard, S Imbeaud, TZ Hirsch, F Liu, V Renault, ... Bioinformatics 34 (19), 3380-3381, 2018 | 65 | 2018 |
BAP1 mutations define a homogeneous subgroup of hepatocellular carcinoma with fibrolamellar-like features and activated PKA TZ Hirsch, A Negulescu, B Gupta, S Caruso, B Noblet, G Couchy, ... Journal of hepatology 72 (5), 924-936, 2020 | 58 | 2020 |
Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study E Trépo, S Caruso, J Yang, S Imbeaud, G Couchy, Q Bayard, E Letouzé, ... The Lancet Oncology 23 (1), 161-171, 2022 | 56 | 2022 |
PrPC from stem cells to cancer S Martin-Lannerée, TZ Hirsch, J Hernandez-Rapp, S Halliez, JL Vilotte, ... Frontiers in cell and developmental biology 2, 55, 2014 | 49 | 2014 |
Integrated genomic analysis identifies driver genes and cisplatin-resistant progenitor phenotype in pediatric liver cancer TZ Hirsch, J Pilet, G Morcrette, A Roehrig, BJ Monteiro, L Molina, ... Cancer discovery 11 (10), 2524-2543, 2021 | 48 | 2021 |
Multi-site tumor sampling highlights molecular intra-tumor heterogeneity in malignant pleural mesothelioma C Meiller, F Montagne, TZ Hirsch, S Caruso, J de Wolf, Q Bayard, ... Genome Medicine 13 (1), 1-16, 2021 | 41 | 2021 |
APC germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structures G Morcrette, TZ Hirsch, E Badour, J Pilet, S Caruso, J Calderaro, Y Martin, ... Oncoimmunology 8 (6), e1583547, 2019 | 40 | 2019 |
PrPC signalling in neurons: from basics to clinical challenges TZ Hirsch, J Hernandez-Rapp, S Martin-Lannerée, JM Launay, ... Biochimie 104, 2-11, 2014 | 38 | 2014 |
The cellular prion protein controls notch signaling in neural stem/progenitor cells S Martin‐Lannerée, S Halliez, TZ Hirsch, J Hernandez‐Rapp, B Passet, ... Stem cells 35 (3), 754-765, 2017 | 32 | 2017 |
A PrPC-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor J Hernandez-Rapp, S Martin-Lannerée, TZ Hirsch, E Pradines, ... Scientific reports 4 (1), 4881, 2014 | 32 | 2014 |
Hijacking PrPc-dependent signal transduction: when prions impair Aβ clearance J Hernandez-Rapp, S Martin-Lannerée, TZ Hirsch, JM Launay, ... Frontiers in aging neuroscience 6, 25, 2014 | 30 | 2014 |
Functions of the prion protein TZ Hirsch, S Martin-Lannerée, S Mouillet-Richard Progress in Molecular Biology and Translational Science 150, 1-34, 2017 | 27 | 2017 |
DNA methylation signatures reveal the diversity of processes remodeling hepatocellular carcinoma methylomes L Meunier, TZ Hirsch, S Caruso, S Imbeaud, Q Bayard, A Roehrig, ... Hepatology 74 (2), 816-834, 2021 | 26 | 2021 |
Epigenetic control of the notch and Eph signaling pathways by the prion protein: implications for prion diseases TZ Hirsch, S Martin-Lannerée, F Reine, J Hernandez-Rapp, L Herzog, ... Molecular Neurobiology 56, 2159-2173, 2019 | 7 | 2019 |
A proof of concept for targeting the PrPC-Amyloid β peptide interaction in basal prostate cancer and mesenchymal colon cancer S Mouillet-Richard, S Martin-Lannerée, D Le Corre, TZ Hirsch, A Ghazi, ... Oncogene 41 (38), 4397-4404, 2022 | 6 | 2022 |