The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 176, S21-S141, 2019 | 754 | 2019 |
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 178, S27-S156, 2021 | 461 | 2021 |
International union of basic and clinical pharmacology. CVII. Structure and pharmacology of the apelin receptor with a recommendation that elabela/toddler is a second … C Read, D Nyimanu, TL Williams, DJ Huggins, P Sulentic, RGC Macrae, ... Pharmacological reviews 71 (4), 467-502, 2019 | 91 | 2019 |
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, AA Mathie, ... British journal of pharmacology 180, S23-S144, 2023 | 70 | 2023 |
The therapeutic potential of apelin in kidney disease FA Chapman, D Nyimanu, JJ Maguire, AP Davenport, DE Newby, ... Nature Reviews Nephrology 17 (12), 840-853, 2021 | 58 | 2021 |
A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension P Yang, C Read, RE Kuc, D Nyimanu, TL Williams, A Crosby, ... British journal of pharmacology 176 (9), 1206-1221, 2019 | 37 | 2019 |
Apelin peptides linked to anti‐serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo C Read, P Yang, RE Kuc, D Nyimanu, TL Williams, RC Glen, LJ Holt, ... Basic & Clinical Pharmacology & Toxicology 126, 96-103, 2020 | 22 | 2020 |
Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites TL Williams, G Strachan, RGC Macrae, RE Kuc, D Nyimanu, AL Paterson, ... Scientific Reports 11 (1), 24336, 2021 | 21 | 2021 |
Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr1]apelin-13 in humans D Nyimanu, RG Kay, P Sulentic, RE Kuc, P Ambery, L Jermutus, ... Scientific Reports 9 (1), 19934, 2019 | 19 | 2019 |
Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer VL Silva, A Kaassis, A Dehsorkhi, CR Koffi, M Severic, M Abdelhamid, ... Biomaterials science 8 (9), 2420-2433, 2020 | 15 | 2020 |
Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection TL Williams, MT Colzani, RGC Macrae, EL Robinson, S Bloor, ... Communications Biology 4 (1), 926, 2021 | 13 | 2021 |
Apelin-36-[L28A] and Apelin-36-[L28C (30kDa-PEG)] peptides that improve diet induced obesity are G protein biased ligands at the apelin receptor D Nyimanu, RE Kuc, TL Williams, M Bednarek, P Ambery, L Jermutus, ... Peptides 121, 170139, 2019 | 13 | 2019 |
The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation … C Read, D Nyimanu, P Yang, RE Kuc, TL Williams, CM Fitzpatrick, ... Frontiers in Pharmacology 11, 588669, 2021 | 12 | 2021 |
Plasma levels of apelin are reduced in patients with liver fibrosis and cirrhosis but are not correlated with circulating levels of bone morphogenetic protein 9 and 10 NE Owen, D Nyimanu, RE Kuc, PD Upton, NW Morrell, GJ Alexander, ... Peptides 136, 170440, 2021 | 9 | 2021 |
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function D Nyimanu, FA Chapman, PJ Gallacher, RE Kuc, TL Williams, DE Newby, ... British journal of clinical pharmacology 88 (12), 5295-5306, 2022 | 6 | 2022 |
In vitro metabolism of synthetic Elabela/Toddler (ELA-32) peptide in human plasma and kidney homogenates analyzed with mass spectrometry and validation of endogenous peptide … D Nyimanu, RG Kay, RE Kuc, AJH Brown, FM Gribble, JJ Maguire, ... Peptides 145, 170642, 2021 | 5 | 2021 |
The role of claudin-2 in kidney function and dysfunction D Nyimanu, C Behm, S Choudhury, ASL Yu Biochemical Society Transactions 51 (4), 1437-1445, 2023 | 3 | 2023 |
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors HA Stephen P, A Christopoulos, PD Anthony, E Kelly, A Mathie, AP John, ... BRITISH JOURNAL OF PHARMACOLOGY 178, 2021 | 2 | 2021 |
BS16 A novel fluorescent apelin ligand tracks apelin receptor internalisation E O’Flaherty, T Williams, D Nyimanu, R Macrae, H Currinn, J Brown, ... Heart 105 (Suppl 6), A151-A151, 2019 | 1 | 2019 |
International Union of Basic and Clinical Pharmacology XXX. Structure and pharmacology of the apelin receptor with a recommendation that Elabela/Toddler is a second endogenous … A Davenport, C Read, D Nyimanu, T Williams, D Huggins, P Sulentic, ... American Society for Pharmacology and Experimental Therapeutics, 2019 | 1 | 2019 |