T cell activation triggers reversible inosine-5′-monophosphate dehydrogenase assembly KC Duong-Ly, YM Kuo, MC Johnson, JM Cote, JM Kollman, J Soboloff, ... Journal of cell science 131 (17), jcs223289, 2018 | 50 | 2018 |
The glycosyltransferases of LPS core: a review of four heptosyltransferase enzymes in context JM Cote, EA Taylor International journal of molecular sciences 18 (11), 2256, 2017 | 44 | 2017 |
Two factor authentication: Asf1 mediates crosstalk between H3 K14 and K56 acetylation JM Cote, YM Kuo, RA Henry, H Scherman, DD Krzizike, AJ Andrews Nucleic acids research 47 (14), 7380-7391, 2019 | 23 | 2019 |
The Stories Tryptophans Tell: Exploring Protein Dynamics of Heptosyltransferase I from Escherichia coli JM Cote, CA Ramirez-Mondragon, ZS Siegel, DJ Czyzyk, J Gao, ... Biochemistry 56 (6), 886-895, 2017 | 18 | 2017 |
Exploring allosteric activation of LigAB from Sphingobium sp. strain SYK-6 through kinetics, mutagenesis and computational studies KP Barry, A Ngu, EF Cohn, JM Cote, AM Burroughs, JP Gerbino, ... Archives of biochemistry and biophysics 567, 35-45, 2015 | 11 | 2015 |
Mulet (mlt) encodes a tubulin-binding cofactor E-like homolog required for spermatid individualization in Drosophila melanogaster JJ Fabrizio, N Aqeel, J Cote, J Estevez, M Jongoy, V Mangal, W Tema, ... Fly 6 (4), 261-272, 2012 | 10 | 2012 |
Synthesis, kinetics and inhibition of Escherichia coli Heptosyltransferase I by monosaccharide analogues of Lipid A NK Nkosana, DJ Czyzyk, ZS Siegel, JM Cote, EA Taylor Bioorganic & medicinal chemistry letters 28 (4), 594-600, 2018 | 9 | 2018 |
Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between the Substrate and Positively Charged Residues JM Cote, CJS Hecht, KR Patel, CA Ramirez-Mondragon, YY Sham, ... Biochemistry 59 (34), 3135-3147, 2020 | 8 | 2020 |
Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action J Milicaj, BA Hassan, JM Cote, CA Ramirez-Mondragon, N Jaunbocus, ... Scientific reports 12 (1), 7302, 2022 | 6 | 2022 |
Preclinical characterization of PRT7732: A highly potent, selective, and orally bioavailable targeted protein degrader of SMARCA2 A Shvartsbart, K Ito, J Rager, M Hulse, A Agarwal, K Vykuntam, J Burtell, ... Cancer Research 84 (6_Supplement), 4503-4503, 2024 | | 2024 |
Abstract B113: Discovery of PRT3789, a first-in-class potent and selective SMARCA2 degrader in clinical trials for the treatment of patients with SMARCA4 mutated cancers K Ito, M Hulse, A Agarwal, J Carter, M Sivakumar, K Vykuntam, M Wang, ... Molecular Cancer Therapeutics 22 (12_Supplement), B113-B113, 2023 | | 2023 |
Discovery of PRT3789, a first-in-class potent and selective SMARCA2 degrader in clinical trials for the treatment of patients with SMARCA4 mutated cancers K Ito, M Hulse, A Agarwal, J Carter, M Sivakumar, K Vykuntam, M Wang, ... MOLECULAR CANCER THERAPEUTICS 22 (12), 2023 | | 2023 |
Selective and orally bioavailable SMARCA2 targeted degraders induce synthetic lethality in SMARCA4-deficient solid tumor K Ito, A Shvartsbart, J Rager, A Agarwal, M Hulse, K Vykuntam, M Wang, ... Cancer Research 83 (7_Supplement), 6277-6277, 2023 | | 2023 |
Discovery of Aminoglycosides as first in class, nanomolar inhibitors of Heptosyltransferase I J Milicaj, B Hassan, JM Cote, CA Ramirez-Mondragon, N Jaunbocus, ... bioRxiv, 2021.10. 03.462930, 2021 | | 2021 |
Pre-acetylation in the presence of Asf1 alters Rtt019-Vps75 selectivity JM Cote, Y Kuo, RA Henry, H Scherman, AJ Andrews | | 2018 |
Pre-acetylation in the presence of Asf1 alters Rtt019-Vps75 selectivity: Two factor authorization: Asf1 mediates crosstalk between H3 K14 and K56 acetylation JM Cote, YM Kuo, RA Henry, H Scherman, AJ Andrews bioRxiv, 389064, 2018 | | 2018 |
Escherichia coli Heptosyltransferase I: Examining Protein Dynamics with Pyrene Excimer Fluorescence and Tryptophan‐Induced Quenching CJS Hecht, JM Cote, DJ Czyzyk, EA Taylor The FASEB Journal 32, 796.15-796.15, 2018 | | 2018 |
Exploring Escherichia coli Heptosyltransferase I Conformational Changes, in an Effort to Probe Dynamic Inhibitors JM Cote | | 2018 |
Alterations of tryptophan residues to allow understanding of protein dynamics of heptosyltransferase I from Escherichia coli J Cote, C Ramirez-Mondragon, Y Sham, E Taylor ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
Investigation of E. coli Heptosyltransferase I Dynamics JM Cote Biophysical Journal 108 (2), 625a, 2015 | | 2015 |