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Joy M. Cote
Joy M. Cote
Fox Chase Cancer Center
在 wesleyan.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
T cell activation triggers reversible inosine-5′-monophosphate dehydrogenase assembly
KC Duong-Ly, YM Kuo, MC Johnson, JM Cote, JM Kollman, J Soboloff, ...
Journal of cell science 131 (17), jcs223289, 2018
502018
The glycosyltransferases of LPS core: a review of four heptosyltransferase enzymes in context
JM Cote, EA Taylor
International journal of molecular sciences 18 (11), 2256, 2017
442017
Two factor authentication: Asf1 mediates crosstalk between H3 K14 and K56 acetylation
JM Cote, YM Kuo, RA Henry, H Scherman, DD Krzizike, AJ Andrews
Nucleic acids research 47 (14), 7380-7391, 2019
232019
The Stories Tryptophans Tell: Exploring Protein Dynamics of Heptosyltransferase I from Escherichia coli
JM Cote, CA Ramirez-Mondragon, ZS Siegel, DJ Czyzyk, J Gao, ...
Biochemistry 56 (6), 886-895, 2017
182017
Exploring allosteric activation of LigAB from Sphingobium sp. strain SYK-6 through kinetics, mutagenesis and computational studies
KP Barry, A Ngu, EF Cohn, JM Cote, AM Burroughs, JP Gerbino, ...
Archives of biochemistry and biophysics 567, 35-45, 2015
112015
Mulet (mlt) encodes a tubulin-binding cofactor E-like homolog required for spermatid individualization in Drosophila melanogaster
JJ Fabrizio, N Aqeel, J Cote, J Estevez, M Jongoy, V Mangal, W Tema, ...
Fly 6 (4), 261-272, 2012
102012
Synthesis, kinetics and inhibition of Escherichia coli Heptosyltransferase I by monosaccharide analogues of Lipid A
NK Nkosana, DJ Czyzyk, ZS Siegel, JM Cote, EA Taylor
Bioorganic & medicinal chemistry letters 28 (4), 594-600, 2018
92018
Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between the Substrate and Positively Charged Residues
JM Cote, CJS Hecht, KR Patel, CA Ramirez-Mondragon, YY Sham, ...
Biochemistry 59 (34), 3135-3147, 2020
82020
Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action
J Milicaj, BA Hassan, JM Cote, CA Ramirez-Mondragon, N Jaunbocus, ...
Scientific reports 12 (1), 7302, 2022
62022
Preclinical characterization of PRT7732: A highly potent, selective, and orally bioavailable targeted protein degrader of SMARCA2
A Shvartsbart, K Ito, J Rager, M Hulse, A Agarwal, K Vykuntam, J Burtell, ...
Cancer Research 84 (6_Supplement), 4503-4503, 2024
2024
Abstract B113: Discovery of PRT3789, a first-in-class potent and selective SMARCA2 degrader in clinical trials for the treatment of patients with SMARCA4 mutated cancers
K Ito, M Hulse, A Agarwal, J Carter, M Sivakumar, K Vykuntam, M Wang, ...
Molecular Cancer Therapeutics 22 (12_Supplement), B113-B113, 2023
2023
Discovery of PRT3789, a first-in-class potent and selective SMARCA2 degrader in clinical trials for the treatment of patients with SMARCA4 mutated cancers
K Ito, M Hulse, A Agarwal, J Carter, M Sivakumar, K Vykuntam, M Wang, ...
MOLECULAR CANCER THERAPEUTICS 22 (12), 2023
2023
Selective and orally bioavailable SMARCA2 targeted degraders induce synthetic lethality in SMARCA4-deficient solid tumor
K Ito, A Shvartsbart, J Rager, A Agarwal, M Hulse, K Vykuntam, M Wang, ...
Cancer Research 83 (7_Supplement), 6277-6277, 2023
2023
Discovery of Aminoglycosides as first in class, nanomolar inhibitors of Heptosyltransferase I
J Milicaj, B Hassan, JM Cote, CA Ramirez-Mondragon, N Jaunbocus, ...
bioRxiv, 2021.10. 03.462930, 2021
2021
Pre-acetylation in the presence of Asf1 alters Rtt019-Vps75 selectivity
JM Cote, Y Kuo, RA Henry, H Scherman, AJ Andrews
2018
Pre-acetylation in the presence of Asf1 alters Rtt019-Vps75 selectivity: Two factor authorization: Asf1 mediates crosstalk between H3 K14 and K56 acetylation
JM Cote, YM Kuo, RA Henry, H Scherman, AJ Andrews
bioRxiv, 389064, 2018
2018
Escherichia coli Heptosyltransferase I: Examining Protein Dynamics with Pyrene Excimer Fluorescence and Tryptophan‐Induced Quenching
CJS Hecht, JM Cote, DJ Czyzyk, EA Taylor
The FASEB Journal 32, 796.15-796.15, 2018
2018
Exploring Escherichia coli Heptosyltransferase I Conformational Changes, in an Effort to Probe Dynamic Inhibitors
JM Cote
2018
Alterations of tryptophan residues to allow understanding of protein dynamics of heptosyltransferase I from Escherichia coli
J Cote, C Ramirez-Mondragon, Y Sham, E Taylor
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
Investigation of E. coli Heptosyltransferase I Dynamics
JM Cote
Biophysical Journal 108 (2), 625a, 2015
2015
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