The distribution, clearance, and brainstem toxicity of panobinostat administered by convection-enhanced delivery WGB Singleton, AS Bienemann, M Woolley, D Johnson, O Lewis, ... Journal of Neurosurgery: Pediatrics 22 (3), 288-296, 2018 | 86 | 2018 |
Convection enhanced delivery of panobinostat (LBH589)-loaded pluronic nano-micelles prolongs survival in the F98 rat glioma model WG Singleton, AM Collins, AS Bienemann, CL Killick-Cole, HR Haynes, ... International journal of nanomedicine, 1385-1399, 2017 | 64 | 2017 |
Therapeutic targeting of histone modifications in adult and pediatric high-grade glioma MJ Williams, WGB Singleton, SP Lowis, K Malik, KM Kurian Frontiers in oncology 7, 45, 2017 | 49 | 2017 |
Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity DJ Asby, CL Killick-Cole, LJ Boulter, WGB Singleton, CA Asby, MJ Wyatt, ... Cancer management and research, 3483-3500, 2018 | 35 | 2018 |
Maximising coverage of brain structures using controlled reflux, convection-enhanced delivery and the recessed step catheter O Lewis, M Woolley, DE Johnson, J Fletcher, J Fenech, MW Pietrzyk, ... Journal of neuroscience methods 308, 337-345, 2018 | 29 | 2018 |
The transcription factor PPARα is overexpressed and is associated with a favourable prognosis in IDH‐wildtype primary glioblastoma HR Haynes, P White, KM Hares, J Redondo, KC Kemp, WGB Singleton, ... Histopathology 70 (7), 1030-1043, 2017 | 27 | 2017 |
Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma CL Killick-Cole, WGB Singleton, AS Bienemann, DJ Asby, MJ Wyatt, ... PLoS One 12 (5), e0176855, 2017 | 27 | 2017 |
Is NICE guidance for identifying lumbar nerve root compression misguided? T Germon, W Singleton, J Hobart European Spine Journal 23, 20-24, 2014 | 21 | 2014 |
Post-operative spinal subdural extra-arachnoid hygroma causing cauda equina compression: a report of two cases WGB Singleton, D Ramnarine, N Patel, C Wigfield British Journal of Neurosurgery 26 (3), 429-431, 2012 | 21 | 2012 |
Oxford textbook of neurological surgery R Kirollos, A Helmy, S Thomson, P Hutchinson Oxford University Press, 2019 | 19 | 2019 |
shRNA‐mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth HR Haynes, HL Scott, CL Killick‐Cole, G Shaw, T Brend, KM Hares, ... The Journal of Pathology 247 (4), 422-434, 2019 | 18 | 2019 |
Chemosensitization of temozolomide-resistant pediatric diffuse midline glioma using potent nanoencapsulated forms of a N (3)-propargyl analogue V Heravi Shargh, J Luckett, K Bouzinab, S Paisey, L Turyanska, ... ACS Applied Materials & Interfaces 13 (30), 35266-35280, 2021 | 16 | 2021 |
Characterization and differential nuclear localization of Nopp140 and a novel Nopp140-like protein in trypanosomes S Kelly, W Singleton, B Wickstead, K Ersfeld, K Gull Eukaryotic Cell 5 (5), 876-879, 2006 | 16 | 2006 |
Extended lumbar drainage in idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis of diagnostic test accuracy AC Nunn, HE Jones, CO Morosanu, WGB Singleton, MA Williams, ... British journal of neurosurgery 35 (3), 285-291, 2021 | 13 | 2021 |
An external ventricular drainage catheter impregnated with rifampicin, trimethoprim and triclosan, with extended activity against MDR Gram-negative bacteria: an in vitro and … R Bayston, W Ashraf, I Pelegrin, K Fowkes, AS Bienemann, ... Journal of Antimicrobial Chemotherapy 74 (10), 2959-2964, 2019 | 13 | 2019 |
Cerebellopontine angle arachnoid cyst containing ectopic choroid plexus—case report WGB Singleton, T Lawrence, AL Green, A Jeans, RSC Kerr Acta neurochirurgica 152, 881-883, 2010 | 12 | 2010 |
Oral microbes and the formation of cerebral abscesses: a single-centre retrospective study H Roy, R Bescos, E McColl, U Rehman, E Cray, LA Belfield, KD Nweze, ... Journal of Dentistry 128, 104366, 2023 | 8 | 2023 |
Amyloidosis presenting as bilateral transudative pleural effusions with normal cardiac investigations: a case report JH Briggs, WG Singleton, MM Burke, LA Hart, RJ Parker Cases Journal 2, 1-3, 2009 | 8 | 2009 |
Deep brain stimulation for facial pain WGB Singleton, R Ashida, NK Patel Neuromodulation for Facial Pain 35, 141-161, 2020 | 7 | 2020 |
NS-21 Multi-catheter intermittent convection-enhanced delivery of carboplatin as a treatment for Diffuse Intrinsic Pontine Glioma (DIPG): Pre-clinical rationale and early … WGB Singleton, NU Barua, J Morgan, AS Bienemann, CL Killick-Cole, ... Neuro-oncology 18 (suppl_3), iii131-iii131, 2016 | 7 | 2016 |