Birth of a Photosynthetic Chassis: A MoClo Toolkit Enabling Synthetic Biology in the Microalga Chlamydomonas reinhardtii P Crozet, FJ Navarro, F Willmund, P Mehrshahi, K Bakowski, KJ Lauersen, ... ACS synthetic biology 7 (9), 2074-2086, 2018 | 234 | 2018 |
Intron-containing algal transgenes mediate efficient recombinant gene expression in the green microalga Chlamydomonas reinhardtii T Baier, J Wichmann, O Kruse, KJ Lauersen Nucleic acids research 46 (13), 6909-6919, 2018 | 150 | 2018 |
Tailored carbon partitioning for phototrophic production of (E)-α-bisabolene from the green microalga Chlamydomonas reinhardtii J Wichmann, T Baier, E Wentnagel, KJ Lauersen, O Kruse Metabolic engineering 45, 211-222, 2018 | 140 | 2018 |
Efficient phototrophic production of a high-value sesquiterpenoid from the eukaryotic microalga Chlamydomonas reinhardtii KJ Lauersen, T Baier, J Wichmann, R Wördenweber, JH Mussgnug, ... Metabolic engineering 38, 331-343, 2016 | 132 | 2016 |
Turning a green alga red: engineering astaxanthin biosynthesis by intragenic pseudogene revival in Chlamydomonas reinhardtii F Perozeni, S Cazzaniga, T Baier, F Zanoni, G Zoccatelli, KJ Lauersen, ... Plant Biotechnology Journal 18 (10), 2053-2067, 2020 | 125 | 2020 |
Phototrophic production of heterologous diterpenoids and a hydroxy-functionalized derivative from Chlamydomonas reinhardtii KJ Lauersen, J Wichmann, T Baier, SC Kampranis, I Pateraki, BL Møller, ... Metabolic engineering 49, 116-127, 2018 | 100 | 2018 |
Introns mediate post-transcriptional enhancement of nuclear gene expression in the green microalga Chlamydomonas reinhardtii T Baier, N Jacobebbinghaus, A Einhaus, KJ Lauersen, O Kruse PLoS genetics 16 (7), e1008944, 2020 | 78 | 2020 |
Patchoulol Production with Metabolically Engineered Corynebacterium glutamicum NA Henke, J Wichmann, T Baier, J Frohwitter, KJ Lauersen, JM Risse, ... Genes 9 (4), 219, 2018 | 70 | 2018 |
Engineered Fusion Proteins for Efficient Protein Secretion and Purification of a Human Growth Factor from the Green Microalga Chlamydomonas reinhardtii T Baier, D Kros, RC Feiner, KJ Lauersen, KM Müller, O Kruse ACS synthetic biology 7 (11), 2547-2557, 2018 | 58 | 2018 |
High cell density cultivation enables efficient and sustainable recombinant polyamine production in the microalga Chlamydomonas reinhardtii RA Freudenberg, T Baier, A Einhaus, L Wobbe, O Kruse Bioresource Technology 323, 124542, 2021 | 56 | 2021 |
Investigating the dynamics of recombinant protein secretion from a microalgal host KJ Lauersen, I Huber, J Wichmann, T Baier, A Leiter, V Gaukel, ... Journal of biotechnology 215, 62-71, 2015 | 49 | 2015 |
Rational promoter engineering enables robust terpene production in microalgae A Einhaus, T Baier, M Rosenstengel, RA Freudenberg, O Kruse ACS Synthetic Biology 10 (4), 847-856, 2021 | 46 | 2021 |
Intronserter, an advanced online tool for design of intron containing transgenes D Jaeger, T Baier, KJ Lauersen Algal Research 42, 101588, 2019 | 40 | 2019 |
OpenTox predictive toxicology framework: toxicological ontology and semantic media wiki-based OpenToxipedia O Tcheremenskaia, R Benigni, I Nikolova, N Jeliazkova, SE Escher, ... Journal of biomedical semantics 3, 1-17, 2012 | 37 | 2012 |
Engineering a powerful green cell factory for robust photoautotrophic diterpenoid production A Einhaus, J Steube, RA Freudenberg, J Barczyk, T Baier, O Kruse Metabolic Engineering 73, 82-90, 2022 | 29 | 2022 |
Characterization of the Brassica napus Flavonol Synthase Gene Family Reveals Bifunctional Flavonol Synthases HM Schilbert, M Schöne, T Baier, M Busche, P Viehöver, B Weisshaar, ... Frontiers in plant science 12, 733762, 2021 | 29 | 2021 |
Engineering astaxanthin accumulation reduces photoinhibition and increases biomass productivity under high light in Chlamydomonas reinhardtii S Cazzaniga, F Perozeni, T Baier, M Ballottari Biotechnology for Biofuels and Bioproducts 15 (1), 77, 2022 | 22 | 2022 |
Advanced pathway engineering for phototrophic putrescine production RA Freudenberg, L Wittemeier, A Einhaus, T Baier, O Kruse Plant Biotechnology Journal 20 (10), 1968-1982, 2022 | 17 | 2022 |
Metabolic Engineering for Efficient Ketocarotenoid Accumulation in the Green Microalga Chlamydomonas reinhardtii S Amendola, JS Kneip, F Meyer, F Perozeni, S Cazzaniga, KJ Lauersen, ... ACS Synthetic Biology 12 (3), 820-831, 2023 | 14 | 2023 |
The Spermidine Synthase Gene SPD1: A Novel Auxotrophic Marker for Chlamydomonas reinhardtii Designed by Enhanced CRISPR/Cas9 Gene Editing RA Freudenberg, L Wittemeier, A Einhaus, T Baier, O Kruse Cells 11 (5), 837, 2022 | 14 | 2022 |