Targeting folate receptor alpha for cancer treatment A Cheung, HJ Bax, DH Josephs, KM Ilieva, G Pellizzari, J Opzoomer, ... Oncotarget 7 (32), 52553, 2016 | 443 | 2016 |
Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation CC Chu, N Ali, P Karagiannis, P Di Meglio, A Skowera, L Napolitano, ... The Journal of experimental medicine 209 (5), 935, 2012 | 307 | 2012 |
AllergoOncology: the role of IgE‐mediated allergy in cancer E Jensen‐Jarolim, G Achatz, MC Turner, S Karagiannis, F Legrand, ... Allergy 63 (10), 1255-1266, 2008 | 242 | 2008 |
Combining immune checkpoint inhibitors: established and emerging targets and strategies to improve outcomes in melanoma DO Khair, HJ Bax, S Mele, S Crescioli, G Pellizzari, A Khiabany, ... Frontiers in immunology 10, 453, 2019 | 237 | 2019 |
IgG4 subclass antibodies impair antitumor immunity in melanoma P Karagiannis, AE Gilbert, DH Josephs, N Ali, T Dodev, L Saul, I Correa, ... The Journal of Clinical Investigation 123 (4), 1457-1474, 2013 | 227 | 2013 |
Diverse matrix metalloproteinase functions regulate cancer amoeboid migration JL Orgaz, P Pandya, R Dalmeida, P Karagiannis, B Sanchez-Laorden, ... Nature communications 5 (1), 4255, 2014 | 202 | 2014 |
Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs) RM Hoffmann, BGT Coumbe, DH Josephs, S Mele, KM Ilieva, A Cheung, ... Oncoimmunology 7 (3), e1395127, 2018 | 165 | 2018 |
Comparison of IgE and IgG antibody‐dependent cytotoxicity in vitro and in a SCID mouse xenograft model of ovarian carcinoma HJ Gould, GA Mackay, SN Karagiannis, CM O'Toole, PJ Marsh, BE Daniel, ... European journal of immunology 29 (11), 3527-3537, 1999 | 159 | 1999 |
Regional activation of myosin II in cancer cells drives tumor progression via a secretory cross-talk with the immune microenvironment M Georgouli, C Herraiz, E Crosas-Molist, B Fanshawe, O Maiques, ... Cell 176 (4), 757-774. e23, 2019 | 154 | 2019 |
IgE-antibody-dependent immunotherapy of solid tumors: cytotoxic and phagocytic mechanisms of eradication of ovarian cancer cells SN Karagiannis, MG Bracher, J Hunt, N McCloskey, RL Beavil, AJ Beavil, ... The Journal of Immunology 179 (5), 2832-2843, 2007 | 144 | 2007 |
An atlas of human regulatory T helper-like cells reveals features of Th2-like Tregs that support a tumorigenic environment L Halim, M Romano, R McGregor, I Correa, P Pavlidis, N Grageda, ... Cell reports 20 (3), 757-770, 2017 | 143 | 2017 |
Activity of human monocytes in IgE antibody‐dependent surveillance and killing of ovarian tumor cells SN Karagiannis, Q Wang, N East, F Burke, S Riffard, MG Bracher, ... European journal of immunology 33 (4), 1030-1040, 2003 | 139 | 2003 |
Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action ZN Willsmore, BGT Coumbe, S Crescioli, S Reci, A Gupta, RJ Harris, ... European Journal of Immunology 51 (3), 544-556, 2021 | 129 | 2021 |
TGF-β-induced transcription sustains amoeboid melanoma migration and dissemination G Cantelli, JL Orgaz, I Rodriguez-Hernandez, P Karagiannis, O Maiques, ... Current biology 25 (22), 2899-2914, 2015 | 124 | 2015 |
IgE antibodies: from structure to function and clinical translation BJ Sutton, AM Davies, HJ Bax, SN Karagiannis Antibodies 8 (1), 19, 2019 | 123 | 2019 |
Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells P Karagiannis, J Singer, J Hunt, SKE Gan, SM Rudman, ... Cancer immunology, immunotherapy 58, 915-930, 2009 | 123 | 2009 |
Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance JL Orgaz, E Crosas-Molist, A Sadok, A Perdrix-Rosell, O Maiques, ... Cancer Cell 37 (1), 85-103. e9, 2020 | 119 | 2020 |
A tool kit for rapid cloning and expression of recombinant antibodies TS Dodev, P Karagiannis, AE Gilbert, DH Josephs, H Bowen, LK James, ... Scientific reports 4 (1), 5885, 2014 | 119 | 2014 |
IgG4 characteristics and functions in cancer immunity S Crescioli, I Correa, P Karagiannis, AM Davies, BJ Sutton, FO Nestle, ... Current allergy and asthma reports 16, 1-11, 2016 | 114 | 2016 |
Revisiting the role of B cells in skin immune surveillance IU Egbuniwe, SN Karagiannis, FO Nestle, KE Lacy Trends in immunology 36 (2), 102-111, 2015 | 114 | 2015 |