Obesity-associated variants within FTO form long-range functional connections with IRX3 S Smemo, JJ Tena, KH Kim, ER Gamazon, NJ Sakabe, C Gómez-Marín, ... Nature 507 (7492), 371-375, 2014 | 1430 | 2014 |
Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis HK Sung, KO Doh, JE Son, JG Park, Y Bae, S Choi, SML Nelson, ... Cell metabolism 17 (1), 61-72, 2013 | 343 | 2013 |
Intermittent fasting promotes adipose thermogenesis and metabolic homeostasis via VEGF-mediated alternative activation of macrophage KH Kim, YH Kim, JE Son, JH Lee, S Kim, MS Choe, JH Moon, J Zhong, ... Cell research 27 (11), 1309-1326, 2017 | 204 | 2017 |
Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K JE Kim, DE Lee, KW Lee, JE Son, SK Seo, J Li, SK Jung, YS Heo, ... Cancer Prevention Research 4 (4), 582-591, 2011 | 127 | 2011 |
Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells KH Choi, JE Kim, NR Song, JE Son, MK Hwang, S Byun, JH Kim, KW Lee, ... Cardiovascular research 85 (4), 836-844, 2010 | 115 | 2010 |
Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo H Jeon, JH Kim, E Lee, YJ Jang, JE Son, JY Kwon, T Lim, S Kim, ... Oncotarget 7 (41), 67223, 2016 | 100 | 2016 |
Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1 JE Kim, JY Kwon, SK Seo, JE Son, SK Jung, SY Min, MK Hwang, YS Heo, ... Biochemical pharmacology 79 (10), 1473-1482, 2010 | 79 | 2010 |
Cocoa polyphenols suppress TNF-α-induced vascular endothelial growth factor expression by inhibiting phosphoinositide 3-kinase (PI3K) and mitogen-activated protein kinase … JE Kim, JE Son, SK Jung, NJ Kang, CY Lee, KW Lee, HJ Lee British Journal of Nutrition 104 (7), 957-964, 2010 | 73 | 2010 |
Dual regulatory functions of SUFU and targetome of GLI2 in SHH subgroup medulloblastoma WC Yin, T Satkunendran, R Mo, S Morrissy, X Zhang, ES Huang, ... Developmental cell 48 (2), 167-183. e5, 2019 | 49 | 2019 |
Licochalcone A, a polyphenol present in licorice, suppresses UV-induced COX-2 expression by targeting PI3K, MEK1, and B-Raf NR Song, JE Kim, JS Park, JR Kim, H Kang, E Lee, YG Kang, JE Son, ... International journal of molecular sciences 16 (3), 4453-4470, 2015 | 46 | 2015 |
Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage SH Shin, SG Seo, S Min, H Yang, E Lee, JE Son, JY Kwon, S Yue, ... Journal of Agricultural and Food Chemistry 62 (19), 4306-4312, 2014 | 45 | 2014 |
Raf and PI3K are the Molecular Targets for the Anti‐metastatic Effect of Luteolin HY Kim, SK Jung, S Byun, JE Son, MH Oh, J Lee, MJ Kang, YS Heo, ... Phytotherapy Research 27 (10), 1481-1488, 2013 | 45 | 2013 |
Thermogenesis-independent metabolic benefits conferred by isocaloric intermittent fasting in ob/ob mice YH Kim, JH Lee, JLH Yeung, E Das, RY Kim, Y Jiang, JH Moon, H Jeong, ... Scientific reports 9 (1), 2479, 2019 | 41 | 2019 |
A novel cinnamon-related natural product with Pim-1 inhibitory activity inhibits leukemia and skin cancer JE Kim, JE Son, H Jeong, DJ Kim, SG Seo, E Lee, TG Lim, JR Kim, ... Cancer research 75 (13), 2716-2728, 2015 | 40 | 2015 |
CDK2 and mTOR are direct molecular targets of isoangustone A in the suppression of human prostate cancer cell growth E Lee, JE Son, S Byun, SJ Lee, YA Kim, K Liu, J Kim, SS Lim, JHY Park, ... Toxicology and applied pharmacology 272 (1), 12-20, 2013 | 37 | 2013 |
Eupatilin, a major flavonoid of Artemisia, attenuates aortic smooth muscle cell proliferation and migration by inhibiting PI3K, MKK3/6, and MKK4 activities JE Son, E Lee, SG Seo, J Lee, JE Kim, J Kim, KW Lee, HJ Lee Planta medica 79 (12), 1009-1016, 2013 | 35 | 2013 |
Luteolin, a novel natural inhibitor of tumor progression locus 2 serine/threonine kinase, inhibits tumor necrosis factor-α-induced cyclooxygenase-2 expression in jb6 mouse … JE Kim, JE Son, YJ Jang, DE Lee, NJ Kang, SK Jung, YS Heo, KW Lee, ... Journal of Pharmacology and Experimental Therapeutics 338 (3), 1013-1022, 2011 | 35 | 2011 |
Brown Pine Leaf Extract and Its Active Component Trans-Communic Acid Inhibit UVB-Induced MMP-1 Expression by Targeting PI3K WB Huh, JE Kim, YG Kang, G Park, T Lim, JY Kwon, DS Song, EH Jeong, ... PLoS One 10 (6), e0128365, 2015 | 30 | 2015 |
Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase JE Son, H Jeong, H Kim, YA Kim, E Lee, HJ Lee, KW Lee Biochemical pharmacology 89 (2), 236-245, 2014 | 29 | 2014 |
Irx3 and Irx5 in Ins2-Cre+ cells regulate hypothalamic postnatal neurogenesis and leptin response JE Son, Z Dou, KH Kim, S Wanggou, VSB Cha, R Mo, X Zhang, X Chen, ... Nature Metabolism 3 (5), 701-713, 2021 | 27 | 2021 |