Global tuberculosis drug development pipeline: the need and the reality Z Ma, C Lienhardt, H McIlleron, AJ Nunn, X Wang The Lancet 375 (9731), 2100-2109, 2010 | 537 | 2010 |
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis F Wang, D Sambandan, R Halder, J Wang, SM Batt, B Weinrick, I Ahmad, ... Proceedings of the National Academy of Sciences 110 (27), E2510-E2517, 2013 | 259 | 2013 |
Organic oxoammonium salts. 3. A new convenient method for the oxidation of alcohols to aldehydes and ketones Z Ma, JM Bobbitt The Journal of Organic Chemistry 56 (21), 6110-6114, 1991 | 253 | 1991 |
Mycobacterium tuberculosis DNA gyrase as a target for drug discovery K Mdluli, Z Ma Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2007 | 200 | 2007 |
Clofazimine analogs with efficacy against experimental tuberculosis and reduced potential for accumulation Y Lu, M Zheng, B Wang, L Fu, W Zhao, P Li, J Xu, H Zhu, H Jin, D Yin, ... Antimicrobial agents and chemotherapy 55 (11), 5185-5193, 2011 | 195 | 2011 |
Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens Z Ma, RF Clark, A Brazzale, S Wang, MJ Rupp, L Li, G Griesgraber, ... Journal of medicinal chemistry 44 (24), 4137-4156, 2001 | 165 | 2001 |
Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens YS Or, RF Clark, S Wang, DTW Chu, AM Nilius, RK Flamm, M Mitten, ... Journal of medicinal chemistry 43 (6), 1045-1049, 2000 | 162 | 2000 |
Design, synthesis, and structure–activity relationship studies of tryptanthrins as antitubercular agents JM Hwang, T Oh, T Kaneko, AM Upton, SG Franzblau, Z Ma, SN Cho, ... Journal of natural products 76 (3), 354-367, 2013 | 133 | 2013 |
Oxoammonium salts. 5. A new synthesis of hindered piperidines leading to unsymmetrical TEMPO-type nitroxides. Synthesis and enantioselective oxidations with chiral nitroxides … Z Ma, Q Huang, JM Bobbitt The Journal of organic chemistry 58 (18), 4837-4843, 1993 | 128 | 1993 |
Synthesis and Structure− Activity Studies of Biphenyl Analogues of the Tuberculosis Drug (6 S)-2-Nitro-6-{[4-(trifluoromethoxy) benzyl] oxy}-6, 7-dihydro-5 H-imidazo [2, 1-b][1 … BD Palmer, AM Thompson, HS Sutherland, A Blaser, I Kmentova, ... Journal of medicinal chemistry 53 (1), 282-294, 2010 | 126 | 2010 |
6-O-substituted ketolides having antibacterial activity YS Or, Z Ma, RF Clark, DT Chu, JJ Plattner, G Griesgraber US Patent 5,866,549, 1999 | 125 | 1999 |
Synthesis, reduction potentials, and antitubercular activity of ring A/B analogues of the bioreductive drug (6 S)-2-nitro-6-{[4-(trifluoromethoxy) benzyl] oxy}-6, 7-dihydro-5 H … AM Thompson, A Blaser, RF Anderson, SS Shinde, SG Franzblau, Z Ma, ... Journal of medicinal chemistry 52 (3), 637-645, 2009 | 124 | 2009 |
Discovery of novel oral protein synthesis inhibitors of Mycobacterium tuberculosis that target leucyl-tRNA synthetase A Palencia, X Li, W Bu, W Choi, CZ Ding, EE Easom, L Feng, ... Antimicrobial agents and chemotherapy 60 (10), 6271-6280, 2016 | 111 | 2016 |
Studies of the Novel Ketolide ABT-773: Transport, Binding to Ribosomes, and Inhibition of Protein Synthesis inStreptococcus pneumoniae JO Capobianco, ZS Cao, VD Shortridge, ZK Ma, RK Flamm, P Zhong Antimicrobial Agents and Chemotherapy 44 (6), 1562-1567, 2000 | 108 | 2000 |
In Vitro and In Vivo Activities of the Nitroimidazole TBA-354 against Mycobacterium tuberculosis AM Upton, S Cho, TJ Yang, Y Kim, Y Wang, Y Lu, B Wang, J Xu, K Mdluli, ... Antimicrobial Agents and Chemotherapy 59 (1), 136-144, 2015 | 106 | 2015 |
Synthesis and Structure− Activity Relationships of 2-Pyridones: A Novel Series of Potent DNA Gyrase Inhibitors as Antibacterial Agents Q Li, DTW Chu, A Claiborne, CS Cooper, CM Lee, K Raye, KB Berst, ... Journal of medicinal chemistry 39 (16), 3070-3088, 1996 | 104 | 1996 |
Drug repositioning in the treatment of malaria and TB A Nzila, Z Ma, K Chibale Future medicinal chemistry 3 (11), 1413-1426, 2011 | 103 | 2011 |
Asymmetric dipolar cycloaddition reactions: a practical, convergent synthesis of chiral pyrrolidines Z Ma, S Wang, CS Cooper, AKL Fung, JK Lynch, F Plagge, DTW Chu Tetrahedron: Asymmetry 8 (6), 883-887, 1997 | 101 | 1997 |
Synthesis and structure− activity relationships of antitubercular 2-nitroimidazooxazines bearing heterocyclic side chains HS Sutherland, A Blaser, I Kmentova, SG Franzblau, B Wan, Y Wang, ... Journal of medicinal chemistry 53 (2), 855-866, 2010 | 100 | 2010 |
Synthesis and structure− activity relationships of aza-and diazabiphenyl analogues of the antitubercular drug (6 S)-2-Nitro-6-{[4-(trifluoromethoxy) benzyl] oxy}-6, 7-dihydro-5 … I Kmentova, HS Sutherland, BD Palmer, A Blaser, SG Franzblau, B Wan, ... Journal of medicinal chemistry 53 (23), 8421-8439, 2010 | 96 | 2010 |