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Paola Pellegrini
Paola Pellegrini
R&D specialist VLVbio
在 vlvbio.com 的电子邮件经过验证
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Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: implications for cancer therapies
P Pellegrini, A Strambi, C Zipoli, M Hägg-Olofsson, M Buoncervello, ...
Autophagy 10 (4), 562-571, 2014
2302014
Autophagy is a protective mechanism for human melanoma cells under acidic stress
ML Marino, P Pellegrini, G Di Lernia, M Djavaheri-Mergny, S Brnjic, ...
Journal of Biological Chemistry 287 (36), 30664-30676, 2012
2062012
Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance
S Avnet, S Lemma, M Cortini, P Pellegrini, F Perut, N Zini, K Kusuzaki, ...
Oncotarget 7 (39), 63408, 2016
952016
Proteasome-associated deubiquitinases and cancer
A Mofers, P Pellegrini, S Linder, P D’Arcy
Cancer and Metastasis Reviews 36, 635-653, 2017
902017
Guidance molecule SEMA3A restricts tumor growth by differentially regulating the proliferation of tumor-associated macrophages
M Wallerius, T Wallmann, M Bartish, J Östling, A Mezheyeuski, NP Tobin, ...
Cancer research 76 (11), 3166-3178, 2016
612016
Obesity modifies the performance of fibrosis biomarkers in nonalcoholic fatty liver disease
S Qadri, N Ahlholm, I Lønsmann, P Pellegrini, A Poikola, PK Luukkonen, ...
The Journal of Clinical Endocrinology & Metabolism 107 (5), e2008-e2020, 2022
432022
Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells
P Pellegrini, M Dyczynski, FV Sbrana, M Karlgren, M Buoncervello, ...
Oncotarget 7 (24), 35703, 2016
432016
SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth
L Ma, W Maruwge, A Strambi, P D'arcy, P Pellegrini, L Kis, A De Milito, ...
Cell death & disease 5 (10), e1483-e1483, 2014
432014
Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs
I Kolosenko, M Fryknäs, S Forsberg, P Johnsson, HJ Cheon, ...
International journal of cancer 136 (4), E51-E61, 2015
382015
Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system
K Selvaraju, A Mofers, P Pellegrini, J Salomonsson, A Ahlner, V Morad, ...
Scientific Reports 9 (1), 9841, 2019
292019
The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damage
X Zhang, P Pellegrini, AA Saei, EK Hillert, M Mazurkiewicz, MH Olofsson, ...
Biochemical Pharmacology 156, 291-301, 2018
292018
A drug screening assay on cancer cells chronically adapted to acidosis
P Pellegrini, JT Serviss, T Lundbäck, N Bancaro, M Mazurkiewicz, ...
Cancer Cell International 18, 1-15, 2018
282018
Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition
M Mazurkiewicz, EK Hillert, X Wang, P Pellegrini, MH Olofsson, ...
Oncotarget 8 (13), 21115, 2017
172017
Induction of ER stress in acute lymphoblastic leukemia cells by the deubiquitinase inhibitor VLX1570
P Pellegrini, K Selvaraju, E Faustini, A Mofers, X Zhang, J Ternerot, ...
International Journal of Molecular Sciences 21 (13), 4757, 2020
162020
A drug-screening model to identify compounds active in cells under metabolic stress
P Pellegrini, T Lundbäck, M Haraldsson, AJ Jensen, A De Milito
Front. Pharmacol. Conference Abstract: 4th Annual Meeting of the …, 2014
22014
Author Correction: Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system
K Selvaraju, A Mofers, P Pellegrini, J Salomonsson, A Ahlner, V Morad, ...
Scientific Reports 9, 2019
2019
Screening and characterization of drugs that inhibit the ubiquitin-proteasome system
K Selvaraju, A Mofers, P Pellegrini, EK Hillert, P D'Arcy, S Linder
Cancer Research 78 (13_Supplement), 2795-2795, 2018
2018
a covalent bond Menu
X Zhang, P Pellegrini, AA Saei, EK Hillert, M Mazurkiewicz, MH Olofsson, ...
2018
Tumor Acidosis in Malignant Progression and Therapy
P Pellegrini
PQDT-Global, 2016
2016
254: Association of interferon stimulated genes and IRF9 upregulation with drug resistance in multicellular spheroids and monolayer cells upon crowding
KP Tamm, I Kolosenko, M Fryknäs, P Johnsson, S Forsberg, S Brnjic, ...
Cytokine 63 (3), 303, 2013
2013
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