Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: implications for cancer therapies P Pellegrini, A Strambi, C Zipoli, M Hägg-Olofsson, M Buoncervello, ... Autophagy 10 (4), 562-571, 2014 | 230 | 2014 |
Autophagy is a protective mechanism for human melanoma cells under acidic stress ML Marino, P Pellegrini, G Di Lernia, M Djavaheri-Mergny, S Brnjic, ... Journal of Biological Chemistry 287 (36), 30664-30676, 2012 | 206 | 2012 |
Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance S Avnet, S Lemma, M Cortini, P Pellegrini, F Perut, N Zini, K Kusuzaki, ... Oncotarget 7 (39), 63408, 2016 | 95 | 2016 |
Proteasome-associated deubiquitinases and cancer A Mofers, P Pellegrini, S Linder, P D’Arcy Cancer and Metastasis Reviews 36, 635-653, 2017 | 90 | 2017 |
Guidance molecule SEMA3A restricts tumor growth by differentially regulating the proliferation of tumor-associated macrophages M Wallerius, T Wallmann, M Bartish, J Östling, A Mezheyeuski, NP Tobin, ... Cancer research 76 (11), 3166-3178, 2016 | 61 | 2016 |
Obesity modifies the performance of fibrosis biomarkers in nonalcoholic fatty liver disease S Qadri, N Ahlholm, I Lønsmann, P Pellegrini, A Poikola, PK Luukkonen, ... The Journal of Clinical Endocrinology & Metabolism 107 (5), e2008-e2020, 2022 | 43 | 2022 |
Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells P Pellegrini, M Dyczynski, FV Sbrana, M Karlgren, M Buoncervello, ... Oncotarget 7 (24), 35703, 2016 | 43 | 2016 |
SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth L Ma, W Maruwge, A Strambi, P D'arcy, P Pellegrini, L Kis, A De Milito, ... Cell death & disease 5 (10), e1483-e1483, 2014 | 43 | 2014 |
Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs I Kolosenko, M Fryknäs, S Forsberg, P Johnsson, HJ Cheon, ... International journal of cancer 136 (4), E51-E61, 2015 | 38 | 2015 |
Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system K Selvaraju, A Mofers, P Pellegrini, J Salomonsson, A Ahlner, V Morad, ... Scientific Reports 9 (1), 9841, 2019 | 29 | 2019 |
The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damage X Zhang, P Pellegrini, AA Saei, EK Hillert, M Mazurkiewicz, MH Olofsson, ... Biochemical Pharmacology 156, 291-301, 2018 | 29 | 2018 |
A drug screening assay on cancer cells chronically adapted to acidosis P Pellegrini, JT Serviss, T Lundbäck, N Bancaro, M Mazurkiewicz, ... Cancer Cell International 18, 1-15, 2018 | 28 | 2018 |
Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition M Mazurkiewicz, EK Hillert, X Wang, P Pellegrini, MH Olofsson, ... Oncotarget 8 (13), 21115, 2017 | 17 | 2017 |
Induction of ER stress in acute lymphoblastic leukemia cells by the deubiquitinase inhibitor VLX1570 P Pellegrini, K Selvaraju, E Faustini, A Mofers, X Zhang, J Ternerot, ... International Journal of Molecular Sciences 21 (13), 4757, 2020 | 16 | 2020 |
A drug-screening model to identify compounds active in cells under metabolic stress P Pellegrini, T Lundbäck, M Haraldsson, AJ Jensen, A De Milito Front. Pharmacol. Conference Abstract: 4th Annual Meeting of the …, 2014 | 2 | 2014 |
Author Correction: Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system K Selvaraju, A Mofers, P Pellegrini, J Salomonsson, A Ahlner, V Morad, ... Scientific Reports 9, 2019 | | 2019 |
Screening and characterization of drugs that inhibit the ubiquitin-proteasome system K Selvaraju, A Mofers, P Pellegrini, EK Hillert, P D'Arcy, S Linder Cancer Research 78 (13_Supplement), 2795-2795, 2018 | | 2018 |
a covalent bond Menu X Zhang, P Pellegrini, AA Saei, EK Hillert, M Mazurkiewicz, MH Olofsson, ... | | 2018 |
Tumor Acidosis in Malignant Progression and Therapy P Pellegrini PQDT-Global, 2016 | | 2016 |
254: Association of interferon stimulated genes and IRF9 upregulation with drug resistance in multicellular spheroids and monolayer cells upon crowding KP Tamm, I Kolosenko, M Fryknäs, P Johnsson, S Forsberg, S Brnjic, ... Cytokine 63 (3), 303, 2013 | | 2013 |