| Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment JAR Salvador, AS Leal, AS Valdeira, BMF Goncalves, DPS Alho, ... European Journal of Medicinal Chemistry 142, 95-130, 2017 | 162 | 2017 |
| Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs JAR Salvador, VM Moreira, BMF Gonçalves, AS Leal, Y Jing Natural product reports 29 (12), 1463-1479, 2012 | 157 | 2012 |
| Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer AS Leal, CR Williams, DB Royce, PA Pioli, MB Sporn, KT Liby Cancer letters 394, 76-87, 2017 | 115 | 2017 |
| Synthesis of novel ursolic acid heterocyclic derivatives with improved abilities of antiproliferation and induction of p53, p21waf1 and NOXA in pancreatic cancer cells AS Leal, R Wang, JAR Salvador, Y Jing Bioorganic & medicinal chemistry 20 (19), 5774-5786, 2012 | 75 | 2012 |
| Highlights of pentacyclic triterpenoids in the cancer settings JAR Salvador, AS Leal, DPS Alho, BMF Gonçalves, AS Valdeira, ... Studies in Natural Products Chemistry 41, 33-73, 2014 | 70 | 2014 |
| A nano-liposome formulation of the PARP inhibitor Talazoparib enhances treatment efficacy and modulates immune cell populations in mammary tumors of BRCA-deficient mice D Zhang, P Baldwin, AS Leal, S Carapellucci, S Sridhar, KT Liby Theranostics 9 (21), 6224, 2019 | 49 | 2019 |
| Synthesis of novel heterocyclic oleanolic acid derivatives with improved antiproliferative activity in solid tumor cells AS Leal, R Wang, JAR Salvador, Y Jing Organic & Biomolecular Chemistry 11 (10), 1726-1738, 2013 | 49 | 2013 |
| Utilização de medidas biométricas para estimar peso vivo em ovinos ES Souza, A Leal, C Barioni, A Matos, J Morais, M Araújo, O Neto, ... Archivos Latinoamericanos de Producción Animal 17 (3), 61-66, 2009 | 40 | 2009 |
| Sustained release talazoparib implants for localized treatment of BRCA1-deficient breast cancer JE Belz, R Kumar, P Baldwin, NC Ojo, AS Leal, DB Royce, D Zhang, ... Theranostics 7 (17), 4340, 2017 | 32 | 2017 |
| Semisynthetic Ursolic Acid Fluorolactone Derivatives Inhibit Growth with Induction of p21waf1 and Induce Apoptosis with Upregulation of NOXA and … AS Leal, R Wang, JAR Salvador, Y Jing ChemMedChem 7 (9), 1635-1646, 2012 | 32 | 2012 |
| The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice AS Leal, SA Misek, EM Lisabeth, RR Neubig, KT Liby Scientific Reports 9 (1), 7072, 2019 | 24 | 2019 |
| Chemoprevention of preclinical breast and lung cancer with the bromodomain inhibitor I-BET 762 D Zhang, AS Leal, S Carapellucci, K Zydeck, MB Sporn, KT Liby Cancer Prevention Research 11 (3), 143-156, 2018 | 23 | 2018 |
| Retinoid X receptor agonist LG100268 modulates the immune microenvironment in preclinical breast cancer models AS Leal, K Zydeck, S Carapellucci, LA Reich, D Zhang, JA Moerland, ... NPJ Breast Cancer 5 (1), 39, 2019 | 22 | 2019 |
| Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1 LE Kolsi, AS Leal, J Yli-Kauhaluoma, KT Liby, VM Moreira Scientific Reports 8 (1), 15923, 2018 | 20 | 2018 |
| Bismuth (III) Triflate‐Based Catalytic Direct Opening of Oleanolic Hydroxy‐γ‐lactones to Afford 12‐Oxo‐28‐carboxylic Acids JAR Salvador, VM Moreira, RMA Pinto, AS Leal, C Le Roux Advanced Synthesis & Catalysis 353 (14‐15), 2637-2642, 2011 | 18 | 2011 |
| Potential therapeutic uses of rexinoids AS Leal, LA Reich, JA Moerland, D Zhang, KT Liby Advances in Pharmacology 91, 141-183, 2021 | 17 | 2021 |
| The bromodomain inhibitor, INCB057643, targets both cancer cells and the tumor microenvironment in two preclinical models of pancreatic cancer AS Leal, P Liu, T Krieger-Burke, B Ruggeri, KT Liby Cancers 13 (1), 96, 2020 | 17 | 2020 |
| Testing novel pyrimidinyl rexinoids: a new paradigm for evaluating rexinoids for cancer prevention D Zhang, AS Leal, S Carapellucci, PH Shahani, JS Bhogal, S Ibrahim, ... Cancer Prevention Research 12 (4), 211-224, 2019 | 16 | 2019 |
| The multi-faceted consequences of NRF2 activation throughout carcinogenesis CJ Occhiuto, JA Moerland, AS Leal, KA Gallo, KT Liby Molecules and cells 46 (3), 176-186, 2023 | 15 | 2023 |
| The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the KrasG12D;Pdx1-Cre (KC) mouse model of pancreatic cancer AS Leal, MB Sporn, PA Pioli, KT Liby Carcinogenesis 37 (12), 1170-1179, 2016 | 13 | 2016 |
