The power to reduce: pyridine nucleotides–small molecules with a multitude of functions N Pollak, C Dölle, M Ziegler Biochemical Journal 402 (2), 205-218, 2007 | 886 | 2007 |
The NAD metabolome—a key determinant of cancer cell biology A Chiarugi, C Dölle, R Felici, M Ziegler Nature Reviews Cancer 12 (11), 741-752, 2012 | 676 | 2012 |
Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation A Nikiforov, C Dölle, M Niere, M Ziegler Journal of Biological Chemistry 286 (24), 21767-21778, 2011 | 380 | 2011 |
Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease C Dölle, I Flønes, GS Nido, H Miletic, N Osuagwu, S Kristoffersen, ... Nature communications 7 (1), 13548, 2016 | 258 | 2016 |
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson’s disease B Brakedal, C Dölle, F Riemer, Y Ma, GS Nido, GO Skeie, AR Craven, ... Cell metabolism 34 (3), 396-407. e6, 2022 | 178 | 2022 |
ADP-ribosylhydrolase 3 (ARH3), not poly (ADP-ribose) glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly (ADP-ribose) M Niere, M Mashimo, L Agledal, C Dölle, A Kasamatsu, J Kato, J Moss, ... Journal of Biological Chemistry 287 (20), 16088-16102, 2012 | 145 | 2012 |
NAD and ADP‐ribose metabolism in mitochondria C Dölle, JGM Rack, M Ziegler The FEBS journal 280 (15), 3530-3541, 2013 | 134 | 2013 |
Neuronal complex I deficiency occurs throughout the Parkinson’s disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage IH Flønes, E Fernandez-Vizarra, M Lykouri, B Brakedal, GO Skeie, ... Acta neuropathologica 135, 409-425, 2018 | 111 | 2018 |
Glitazone use associated with reduced risk of Parkinson's disease B Brakedal, I Flønes, SF Reiter, Ø Torkildsen, C Dölle, J Assmus, ... Movement Disorders 32 (11), 1594-1599, 2017 | 98 | 2017 |
Generation, release, and uptake of the NAD precursor nicotinic acid riboside by human cells V Kulikova, K Shabalin, K Nerinovski, C Dölle, M Niere, A Yakimov, ... Journal of Biological Chemistry 290 (45), 27124-27137, 2015 | 97 | 2015 |
Subcellular distribution of NAD+ between cytosol and mitochondria determines the metabolic profile of human cells MR VanLinden, C Dölle, IKN Pettersen, VA Kulikova, M Niere, G Agrimi, ... Journal of Biological Chemistry 290 (46), 27644-27659, 2015 | 92 | 2015 |
NAD biosynthesis in humans-enzymes, metabolites and therapeutic aspects C Dölle, R Hvidsten Skoge, M R VanLinden, M Ziegler Current topics in medicinal chemistry 13 (23), 2907-2917, 2013 | 91 | 2013 |
Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases C Lau, C Dölle, TI Gossmann, L Agledal, M Niere, M Ziegler Journal of biological chemistry 285 (24), 18868-18876, 2010 | 86 | 2010 |
Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation C Dölle, M Niere, E Lohndal, M Ziegler Cellular and molecular life sciences 67, 433-443, 2010 | 84 | 2010 |
Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain L Toker, GT Tran, J Sundaresan, OB Tysnes, G Alves, K Haugarvoll, ... Molecular neurodegeneration 16, 1-20, 2021 | 79 | 2021 |
Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels RH Skoge, C Dölle, M Ziegler DNA repair 23, 33-38, 2014 | 72 | 2014 |
Identification of the nicotinamide salvage pathway as a new toxification route for antimetabolites D Buonvicino, F Mazzola, F Zamporlini, F Resta, G Ranieri, E Camaioni, ... Cell chemical biology 25 (4), 471-482. e7, 2018 | 68 | 2018 |
NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms NR Love, N Pollak, C Dölle, M Niere, Y Chen, P Oliveri, E Amaya, S Patel, ... Proceedings of the National Academy of Sciences 112 (5), 1386-1391, 2015 | 60 | 2015 |
Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease GS Nido, C Dölle, I Flønes, HA Tuppen, G Alves, OB Tysnes, K Haugarvoll, ... Neurobiology of aging 63, 120-127, 2018 | 57 | 2018 |
Novel SLC19A3 Promoter Deletion and Allelic Silencing in Biotin-Thiamine-Responsive Basal Ganglia Encephalopathy I Flønes, P Sztromwasser, K Haugarvoll, C Dölle, M Lykouri, ... PLoS One 11 (2), e0149055, 2016 | 28 | 2016 |