An optimized Protocol for Human M2 Macrophages using M‐CSF and IL‐4/IL‐10/TGF‐β Yields a Dominant Immunosuppressive Phenotype S Mia, A Warnecke, XM Zhang, V Malmström, RA Harris Scandinavian journal of immunology 79 (5), 305-314, 2014 | 278 | 2014 |
Adoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD mice R Parsa, P Andresen, A Gillett, S Mia, XM Zhang, S Mayans, D Holmberg, ... Diabetes 61 (11), 2881-2892, 2012 | 241 | 2012 |
Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells H Lund, M Pieber, R Parsa, J Han, D Grommisch, E Ewing, L Kular, ... Nature communications 9 (1), 4845, 2018 | 189 | 2018 |
Kainic acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines XM Zhang, J Zhu Current neuropharmacology 9 (2), 388-398, 2011 | 164 | 2011 |
An updated assessment of microglia depletion: current concepts and future directions J Han, RA Harris, XM Zhang Molecular brain 10, 1-8, 2017 | 156 | 2017 |
Protein arginine methyltransferase 1: positively charged residues in substrate peptides distal to the site of methylation are important for substrate binding and catalysis TC Osborne, O Obianyo, X Zhang, X Cheng, PR Thompson Biochemistry 46 (46), 13370-13381, 2007 | 152 | 2007 |
Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp A Stetler, C Winograd, J Sayegh, A Cheever, E Patton, X Zhang, S Clarke, ... Human molecular genetics 15 (1), 87-96, 2006 | 136 | 2006 |
Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development J Wang, Z Cao, XM Zhang, M Nakamura, M Sun, J Hartman, RA Harris, ... Cancer research 75 (2), 306-315, 2015 | 133 | 2015 |
Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA E Blackwell, X Zhang, S Ceman Human molecular genetics 19 (7), 1314-1323, 2010 | 128 | 2010 |
Human macrophages induce CD4+Foxp3+ regulatory T cells via binding and re‐release of TGF‐β A Schmidt, XM Zhang, RN Joshi, S Iqbal, C Wahlund, S Gabrielsson, ... Immunology and cell biology 94 (8), 747-762, 2016 | 112 | 2016 |
Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders J Han, K Zhu, XM Zhang, RA Harris Glia 67 (2), 217-231, 2019 | 97 | 2019 |
Adoptive transfer of cytokine‐induced immunomodulatory adult microglia attenuates experimental autoimmune encephalomyelitis in DBA/1 mice XM Zhang, H Lund, S Mia, R Parsa, RA Harris Glia 62 (5), 804-817, 2014 | 90 | 2014 |
BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis R Parsa, H Lund, AM Georgoudaki, XM Zhang, A Ortlieb Guerreiro-Cacais, ... Journal of Experimental Medicine 213 (8), 1537-1553, 2016 | 85 | 2016 |
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling H Lund, M Pieber, R Parsa, D Grommisch, E Ewing, L Kular, J Han, K Zhu, ... Nature immunology 19 (5), 1-7, 2018 | 68 | 2018 |
Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress T Yang, XM Zhang, L Tarnawski, M Peleli, Z Zhuge, N Terrando, ... Redox biology 13, 320-330, 2017 | 68 | 2017 |
Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia W Han, T Umekawa, K Zhou, XM Zhang, M Ohshima, CA Dominguez, ... Oncotarget 7 (50), 82305, 2016 | 62 | 2016 |
Gender differences in susceptibility to kainic acid-induced neurodegeneration in aged C57BL/6 mice XM Zhang, SW Zhu, RS Duan, AH Mohammed, B Winblad, J Zhu Neurotoxicology 29 (3), 406-412, 2008 | 59 | 2008 |
Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses T Yang, X Gao, M Sandberg, C Zollbrecht, XM Zhang, M Hezel, M Liu, ... Diabetologia 58, 1610-1620, 2015 | 48 | 2015 |
TNF‐α receptor 1 deficiency enhances kainic acid–induced hippocampal injury in mice MO Lu, XM Zhang, E Mix, HC Quezada, T Jin, J Zhu, A Adem Journal of neuroscience research 86 (7), 1608-1614, 2008 | 46 | 2008 |
Altered cerebrospinal fluid index of prealbumin, fibrinogen, and haptoglobin in patients with Guillain–Barré syndrome and chronic inflammatory demyelinating polyneuropathy HL Zhang, XM Zhang, XJ Mao, H Deng, HF Li, R Press, S Fredrikson, ... Acta Neurologica Scandinavica 125 (2), 129-135, 2012 | 45 | 2012 |