Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks D Iliopoulos, KN Malizos, P Oikonomou, A Tsezou PloS one 3 (11), e3740, 2008 | 594 | 2008 |
Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism T Simopoulou, KN Malizos, D Iliopoulos, N Stefanou, L Papatheodorou, ... Osteoarthritis and Cartilage 15 (8), 872-883, 2007 | 366 | 2007 |
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations CG Boer, K Hatzikotoulas, L Southam, L Stefánsdóttir, Y Zhang, ... Cell 184 (18), 4784-4818. e17, 2021 | 301 | 2021 |
A genome‐wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22 HJM Kerkhof, RJ Lories, I Meulenbelt, I Jonsdottir, AM Valdes, P Arp, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2010 | 281 | 2010 |
Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention D Iliopoulos, KN Malizos, A Tsezou Annals of the rheumatic diseases 66 (12), 1616-1621, 2007 | 248 | 2007 |
Large‐scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand E Evangelou, K Chapman, I Meulenbelt, FB Karassa, J Loughlin, A Carr, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 236 | 2009 |
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility K Chapman, A Takahashi, I Meulenbelt, C Watson, J Rodriguez-Lopez, ... Human molecular genetics 17 (10), 1497-1504, 2008 | 222 | 2008 |
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22 E Evangelou, AM Valdes, HJM Kerkhof, U Styrkarsdottir, YY Zhu, ... Annals of the rheumatic diseases 70 (2), 349-355, 2011 | 199 | 2011 |
Lipid metabolism and osteoarthritis: lessons from atherosclerosis V Gkretsi, T Simopoulou, A Tsezou Progress in lipid research 50 (2), 133-140, 2011 | 193 | 2011 |
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip E Evangelou, HJ Kerkhof, U Styrkarsdottir, EE Ntzani, SD Bos, T Esko, ... Annals of the rheumatic diseases 73 (12), 2130-2136, 2014 | 172 | 2014 |
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study K Panoutsopoulou, L Southam, KS Elliott, N Wrayner, G Zhai, C Beazley, ... Annals of the rheumatic diseases 70 (5), 864-867, 2011 | 170 | 2011 |
Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes E Ntoumou, M Tzetis, M Braoudaki, G Lambrou, M Poulou, K Malizos, ... Clinical epigenetics 9, 1-15, 2017 | 146 | 2017 |
New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study M Nakajima, A Takahashi, I Kou, C Rodriguez-Fontenla, JJ Gomez-Reino, ... PloS one 5 (3), e9723, 2010 | 146 | 2010 |
Assessment of osteoarthritis candidate genes in a meta‐analysis of nine genome‐wide association studies C Rodriguez‐Fontenla, M Calaza, E Evangelou, AM Valdes, N Arden, ... Arthritis & Rheumatology 66 (4), 940-949, 2014 | 145 | 2014 |
Impaired expression of genes regulating cholesterol efflux in human osteoarthritic chondrocytes A Tsezou, D Iliopoulos, KN Malizos, T Simopoulou Journal of Orthopaedic Research 28 (8), 1033-1039, 2010 | 143 | 2010 |
Osteoarthritis year in review 2014: genetics and genomics A Tsezou Osteoarthritis and cartilage 22 (12), 2017-2024, 2014 | 132 | 2014 |
Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity … I Papathanasiou, KN Malizos, A Tsezou Arthritis research & therapy 14, 1-14, 2012 | 124 | 2012 |
Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium HJM Kerkhof, I Meulenbelt, T Akune, NK Arden, A Aromaa, ... Osteoarthritis and Cartilage 19 (3), 254-264, 2011 | 117 | 2011 |
Meta-analysis of association between the ASPN D-repeat and osteoarthritis T Nakamura, D Shi, M Tzetis, J Rodriguez-Lopez, Y Miyamoto, A Tsezou, ... Human molecular genetics 16 (14), 1676-1681, 2007 | 114 | 2007 |
Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase N Stefanou, V Papanikolaou, Y Furukawa, Y Nakamura, A Tsezou BMC cancer 10, 1-10, 2010 | 98 | 2010 |