Grass pollen immunotherapy induces mucosal and peripheral IL-10 responses and blocking IgG activity KT Nouri-Aria, PA Wachholz, JN Francis, MR Jacobson, SM Walker, ... The Journal of Immunology 172 (5), 3252-3259, 2004 | 728 | 2004 |
Cell2location maps fine-grained cell types in spatial transcriptomics V Kleshchevnikov, A Shmatko, E Dann, A Aivazidis, HW King, T Li, ... Nature biotechnology 40 (5), 661-671, 2022 | 523 | 2022 |
Cross-tissue immune cell analysis reveals tissue-specific features in humans C Domínguez Conde, C Xu, LB Jarvis, DB Rainbow, SB Wells, T Gomes, ... Science 376 (6594), eabl5197, 2022 | 473 | 2022 |
Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies LK James, MH Shamji, SM Walker, DR Wilson, PA Wachholz, JN Francis, ... Journal of Allergy and Clinical Immunology 127 (2), 509-516. e5, 2011 | 389 | 2011 |
Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity JN Francis, LK James, G Paraskevopoulos, C Wong, MA Calderon, ... Journal of Allergy and Clinical Immunology 121 (5), 1120-1125. e2, 2008 | 382 | 2008 |
Grass pollen immunotherapy induces an allergen-specific IgA2 antibody response associated with mucosal TGF-β expression C Pilette, KT Nouri-Aria, MR Jacobson, LK Wilcock, B Detry, SM Walker, ... The Journal of Immunology 178 (7), 4658-4666, 2007 | 308 | 2007 |
IgG 4 inhibits peanut-induced basophil and mast cell activation in peanut-tolerant children sensitized to peanut major allergens AF Santos, LK James, HT Bahnson, MH Shamji, NC Couto-Francisco, ... Journal of Allergy and Clinical Immunology 135 (5), 1249-1256, 2015 | 274 | 2015 |
Distinct microbial and immune niches of the human colon KR James, T Gomes, R Elmentaite, N Kumar, EL Gulliver, HW King, ... Nature Immunology 21 (3), 343-353, 2020 | 229 | 2020 |
Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics HW King, N Orban, JC Riches, AJ Clear, G Warnes, SA Teichmann, ... Science Immunology 6 (56), eabe6291, 2021 | 205 | 2021 |
Proinsulin peptide immunotherapy in type 1 diabetes: report of a first‐in‐man Phase I safety study SL Thrower, L James, W Hall, KM Green, S Arif, JS Allen, C Van‐Krinks, ... Clinical & Experimental Immunology 155 (2), 156-165, 2009 | 183 | 2009 |
Update on mechanisms of allergen injection immunotherapy LK James, SR Durham Clinical & Experimental Allergy 38 (7), 1074-1088, 2008 | 181 | 2008 |
The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses MH Shamji, LK Wilcock, PA Wachholz, RJ Dearman, I Kimber, ... Journal of immunological methods 317 (1-2), 71-79, 2006 | 167 | 2006 |
Deep sequencing of B cell receptor repertoires from COVID-19 patients reveals strong convergent immune signatures JD Galson, S Schaetzle, RJM Bashford-Rogers, MIJ Raybould, ... Frontiers in immunology 11, 605170, 2020 | 133 | 2020 |
Potential mechanisms for IgG4 inhibition of immediate hypersensitivity reactions LK James, SJ Till Current allergy and asthma reports 16, 1-7, 2016 | 132 | 2016 |
A tool kit for rapid cloning and expression of recombinant antibodies TS Dodev, P Karagiannis, AE Gilbert, DH Josephs, H Bowen, LK James, ... Scientific reports 4 (1), 5885, 2014 | 120 | 2014 |
The ocrelizumab phase II extension trial suggests the potential to improve the risk: Benefit balance in multiple sclerosis. D Baker, G Pryce, LK James, M Marta, K Schmierer Multiple Sclerosis and Related Disorders 44, 102279, 2020 | 104 | 2020 |
Allergen specificity of IgG 4-expressing B cells in patients with grass pollen allergy undergoing immunotherapy LK James, H Bowen, RA Calvert, TS Dodev, MH Shamji, AJ Beavil, ... Journal of Allergy and Clinical Immunology 130 (3), 663-670. e3, 2012 | 94 | 2012 |
Comprehensive mapping of tissue cell architecture via integrated single cell and spatial transcriptomics V Kleshchevnikov, A Shmatko, E Dann, A Aivazidis, HW King, T Li, ... BioRxiv, 2020.11. 15.378125, 2020 | 76 | 2020 |
Inhibition of allergen‐dependent IgE activity by antibodies of the same specificity but different class TS Dodev, H Bowen, MH Shamji, HJ Bax, AJ Beavil, JM McDonnell, ... Allergy 70 (6), 720-724, 2015 | 71 | 2015 |
Aluminium hydroxide down‐regulates T helper 2 responses by allergen‐stimulated human peripheral blood mononuclear cells LK Wilcock, JN Francis, SR Durham Clinical & Experimental Allergy 34 (9), 1373-1378, 2004 | 62 | 2004 |