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Structures of the bacterial ribosome at 3.5 A resolution BS Schuwirth, MA Borovinskaya, CW Hau, W Zhang, A Vila-Sanjurjo, ... Science 310 (5749), 827-834, 2005 | 1647 | 2005 |
Accessing protein conformational ensembles using room-temperature X-ray crystallography JS Fraser, H Van Den Bedem, AJ Samelson, PT Lang, JM Holton, ... Proceedings of the National Academy of Sciences 108 (39), 16247-16252, 2011 | 604 | 2011 |
An assessment of the resolution limitation due to radiation-damage in x-ray diffraction microscopy MR Howells, T Beetz, HN Chapman, C Cui, JM Holton, CJ Jacobsen, ... Journal of electron spectroscopy and related phenomena 170 (1-3), 4-12, 2009 | 538 | 2009 |
Structures of the intermediates of Kok’s photosynthetic water oxidation clock J Kern, R Chatterjee, ID Young, FD Fuller, L Lassalle, M Ibrahim, S Gul, ... Nature 563 (7731), 421-425, 2018 | 478 | 2018 |
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling MA Borovinskaya, RD Pai, W Zhang, BS Schuwirth, JM Holton, ... Nature structural & molecular biology 14 (8), 727-732, 2007 | 430 | 2007 |
Large language models generate functional protein sequences across diverse families A Madani, B Krause, ER Greene, S Subramanian, BP Mohr, JM Holton, ... Nature Biotechnology 41 (8), 1099-1106, 2023 | 428 | 2023 |
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1 H Walden, MS Podgorski, DT Huang, DW Miller, RJ Howard, DL Minor, ... Molecular cell 12 (6), 1427-1437, 2003 | 304 | 2003 |
A beginner's guide to radiation damage JM Holton Journal of synchrotron radiation 16 (2), 133-142, 2009 | 299 | 2009 |
Ubiquitin recognition by the human TSG101 protein WI Sundquist, HL Schubert, BN Kelly, GC Hill, JM Holton, CP Hill Molecular cell 13 (6), 783-789, 2004 | 285 | 2004 |
Time-resolved protein nanocrystallography using an X-ray free-electron laser A Aquila, MS Hunter, RB Doak, RA Kirian, P Fromme, TA White, ... Optics express 20 (3), 2706-2716, 2012 | 276 | 2012 |
Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity DT Huang, HW Hunt, M Zhuang, MD Ohi, JM Holton, BA Schulman Nature 445 (7126), 394-398, 2007 | 274 | 2007 |
Automated protein crystal structure determination using ELVES J Holton, T Alber Proceedings of the National Academy of Sciences 101 (6), 1537-1542, 2004 | 273 | 2004 |
Structural and mechanistic studies of VPS4 proteins A Scott, HY Chung, M Gonciarz‐Swiatek, GC Hill, FG Whitby, J Gaspar, ... The EMBO journal 24 (20), 3658-3669, 2005 | 272 | 2005 |
Femtosecond protein nanocrystallography—data analysis methods RA Kirian, X Wang, U Weierstall, KE Schmidt, JCH Spence, M Hunter, ... Optics express 18 (6), 5713-5723, 2010 | 254 | 2010 |
Crystallographic analysis of CD40 recognition and signaling by human TRAF2 SM McWhirter, SS Pullen, JM Holton, JJ Crute, MR Kehry, T Alber Proceedings of the National Academy of Sciences 96 (15), 8408-8413, 1999 | 254 | 1999 |
Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source S Classen, GL Hura, JM Holton, RP Rambo, I Rodic, PJ McGuire, K Dyer, ... Journal of applied crystallography 46 (1), 1-13, 2013 | 253 | 2013 |
Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1 DT Huang, A Paydar, M Zhuang, MB Waddell, JM Holton, BA Schulman Molecular cell 17 (3), 341-350, 2005 | 233 | 2005 |
The minimum crystal size needed for a complete diffraction data set JM Holton, KA Frankel Acta Crystallographica Section D: Biological Crystallography 66 (4), 393-408, 2010 | 217 | 2010 |
Radiation damage in protein serial femtosecond crystallography using an x-ray free-electron laser L Lomb, TRM Barends, S Kassemeyer, A Aquila, SW Epp, B Erk, L Foucar, ... Physical Review B—Condensed Matter and Materials Physics 84 (21), 214111, 2011 | 207 | 2011 |