Extracellular chaperones and proteostasis AR Wyatt, JJ Yerbury, H Ecroyd, MR Wilson Annual review of biochemistry 82 (1), 295-322, 2013 | 193 | 2013 |
Quality control of protein folding in extracellular space JJ Yerbury, EM Stewart, AR Wyatt, MR Wilson EMBO reports 6 (12), 1131-1136, 2005 | 175 | 2005 |
Clusterin facilitates in vivo clearance of extracellular misfolded proteins AR Wyatt, JJ Yerbury, P Berghofer, I Greguric, A Katsifis, CM Dobson, ... Cellular and Molecular Life Sciences 68, 3919-3931, 2011 | 164 | 2011 |
Structural characterization of clusterin-chaperone client protein complexes AR Wyatt, JJ Yerbury, MR Wilson Journal of Biological Chemistry 284 (33), 21920-21927, 2009 | 95 | 2009 |
The chaperone action of Clusterin and its putative role in quality control of extracellular protein folding A Wyatt, J Yerbury, S Poon, R Dabbs, M Wilson Advances in cancer research 104, 89-114, 2009 | 91 | 2009 |
Hypochlorite-induced structural modifications enhance the chaperone activity of human α2-macroglobulin AR Wyatt, JR Kumita, RW Mifsud, CA Gooden, MR Wilson, CM Dobson Proceedings of the National Academy of Sciences 111 (20), E2081-E2090, 2014 | 88 | 2014 |
Alpha‐2‐macroglobulin, a hypochlorite‐regulated chaperone and immune system modulator JH Cater, MR Wilson, AR Wyatt Oxidative medicine and cellular longevity 2019 (1), 5410657, 2019 | 85 | 2019 |
Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia-and Alzheimer’s-associated amyloid beta peptide JH Cater, JR Kumita, R Zeineddine Abdallah, G Zhao, ... Proceedings of the National Academy of Sciences 116 (13), 6101-6110, 2019 | 73 | 2019 |
Roles of extracellular chaperones in amyloidosis AR Wyatt, JJ Yerbury, RA Dabbs, MR Wilson Journal of molecular biology 421 (4-5), 499-516, 2012 | 71 | 2012 |
Protease-activated alpha-2-macroglobulin can inhibit amyloid formation via two distinct mechanisms AR Wyatt, P Constantinescu, H Ecroyd, CM Dobson, MR Wilson, ... FEBS letters 587 (5), 398-403, 2013 | 60 | 2013 |
Identification of human plasma proteins as major clients for the extracellular chaperone clusterin AR Wyatt, MR Wilson Journal of Biological Chemistry 285 (6), 3532-3539, 2010 | 58 | 2010 |
Acute phase proteins are major clients for the chaperone action of α2-macroglobulin in human plasma AR Wyatt, MR Wilson Cell Stress and Chaperones 18 (2), 161-170, 2013 | 40 | 2013 |
PZP and PAI-2: Structurally-diverse, functionally similar pregnancy proteins? AR Wyatt, JH Cater, M Ranson The International Journal of Biochemistry & Cell Biology 79, 113-117, 2016 | 39 | 2016 |
Extracellular chaperones RA Dabbs, AR Wyatt, JJ Yerbury, H Ecroyd, MR Wilson | 35 | 2010 |
Alpha-2-macroglobulin is acutely sensitive to freezing and lyophilization: Implications for structural and functional studies AR Wyatt, JR Kumita, NE Farrawell, CM Dobson, MR Wilson PLoS One 10 (6), e0130036, 2015 | 31 | 2015 |
Amorphous protein aggregates stimulate plasminogen activation, leading to release of cytotoxic fragments that are clients for extracellular chaperones P Constantinescu, RA Brown, AR Wyatt, M Ranson, MR Wilson Journal of Biological Chemistry 292 (35), 14425-14437, 2017 | 30 | 2017 |
Therapeutic targets in extracellular protein deposition diseases AR Wyatt, JJ Yerbury, S Poon, MR Wilson Current medicinal chemistry 16 (22), 2855-2866, 2009 | 27 | 2009 |
Hypochlorite-induced aggregation of fibrinogen underlies a novel antioxidant role in blood plasma N Manucat-Tan, RZ Abdallah, H Kaur, D Saviane, MR Wilson, AR Wyatt Redox biology 40, 101847, 2021 | 13 | 2021 |
A novel role for plasminogen activator inhibitor type-2 as a hypochlorite-resistant serine protease inhibitor and holdase chaperone JH Cater, NB Mañucat-Tan, DK Georgiou, G Zhao, IA Buhimschi, ... Cells 11 (7), 1152, 2022 | 6 | 2022 |
Music in medical education: A critical interpretive synthesis AR Orchard, J Sitoh, A Wyatt, M Moore Medical Education 58 (5), 507-522, 2024 | 3 | 2024 |