| A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer MK Muellner, IZ Uras, BV Gapp, C Kerzendorfer, M Smida, ... Nature chemical biology 7 (11), 787-793, 2011 | 199 | 2011 |
| Targeting KRAS Mutant Non-Small-Cell Lung Cancer: Past, Present and Future IZ Uras, HP Moll, E Casanova International Journal of Molecular Sciences 21 (12), 4325, 2020 | 131 | 2020 |
| Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6 IZ Uras, GJ Walter, R Scheicher, F Bellutti, M Prchal-Murphy, AS Tigan, ... Blood, The Journal of the American Society of Hematology 127 (23), 2890-2902, 2016 | 108 | 2016 |
| Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis A Perne, MK Muellner, M Steinrueck, N Craig-Mueller, J Mayerhofer, ... PloS one 4 (12), e8292, 2009 | 96 | 2009 |
| Normal and pathological erythropoiesis in adults: from gene regulation to targeted treatment concepts P Valent, G Büsche, I Theurl, IZ Uras, U Germing, R Stauder, K Sotlar, ... haematologica 103 (10), 1593, 2018 | 84 | 2018 |
| STAT3: versatile functions in non-small cell lung cancer J Mohrherr, IZ Uras, HP Moll, E Casanova Cancers 12 (5), 1107, 2020 | 80 | 2020 |
| CDK6 antagonizes p53-induced responses during tumorigenesis F Bellutti, AS Tigan, S Nebenfuehr, M Dolezal, M Zojer, R Grausenburger, ... Cancer discovery 8 (7), 884-897, 2018 | 71 | 2018 |
| PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis A Berger, A Hoelbl-Kovacic, J Bourgeais, L Hoefling, W Warsch, ... Leukemia 28 (3), 629-641, 2014 | 67 | 2014 |
| A kinase-independent role for CDK8 in BCR-ABL1+ leukemia I Menzl, T Zhang, A Berger-Becvar, R Grausenburger, G Heller, ... Nature communications 10 (1), 4741, 2019 | 41 | 2019 |
| MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated M Smida, F Fece de La Cruz, C Kerzendorfer, IZ Uras, B Mair, A Mazouzi, ... Nature communications 7 (1), 13701, 2016 | 40 | 2016 |
| CDK6 coordinates JAK2V617F mutant MPN via NF-κB and apoptotic networks IZ Uras, B Maurer, H Nivarthi, P Jodl, K Kollmann, M Prchal-Murphy, ... Blood, The Journal of the American Society of Hematology 133 (15), 1677-1690, 2019 | 37 | 2019 |
| CDK6 inhibition: A novel approach in AML management IZ Uras, V Sexl, K Kollmann International Journal of Molecular Sciences 21 (7), 2528, 2020 | 35 | 2020 |
| Cdk6 contributes to cytoskeletal stability in erythroid cells IZ Uras, RM Scheicher, K Kollmann, M Glösmann, M Prchal-Murphy, ... Haematologica 102 (6), 995, 2017 | 26 | 2017 |
| Ubiquitin-specific protease 4 inhibits mono-ubiquitination of the master growth factor signaling kinase PDK1 IZ Uras, T List, SMB Nijman PLoS One 7 (2), e31003, 2012 | 26 | 2012 |
| Targeted protein degradation: clinical advances in the field of oncology AKAA Salama, MV Trkulja, E Casanova, IZ Uras International Journal of Molecular Sciences 23 (23), 15440, 2022 | 17 | 2022 |
| Therapeutic Vulnerabilities in FLT3-Mutant AML Unmasked by Palbociclib IZ Uras, B Maurer, S Nebenfuehr, M Zojer, P Valent, V Sexl International Journal of Molecular Sciences 19 (12), 3987, 2018 | 17 | 2018 |
| TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens MK Muellner, G Duernberger, F Ganglberger, C Kerzendorfer, IZ Uras, ... BMC bioinformatics 15, 1-13, 2014 | 7 | 2014 |
| p27 in FLT3-driven acute myeloid leukemia: many roads lead to ruin IZ Uras, F Bellutti, V Sexl haematologica 102 (8), 1299, 2017 | 4 | 2017 |
| Cdk6’s functions are critically regulated by its unique C-terminus A Schirripa, H Schöppe, S Nebenfuehr, M Zojer, T Klampfl, V Kugler, ... iScience, 2024 | | 2024 |
| CDK6 is an essential signaling node in JAK2V617F-mutant MPN B Maurer, IZ Uras, S Kollmann, P Jodl, K Kollmann, M Prchal-Murphy, ... FEBS OPEN BIO 9, 355-356, 2019 | | 2019 |
