Essential elements in depression and anxiety. Part I K Młyniec, CL Davies, IG de Agüero Sánchez, K Pytka, B Budziszewska, ... Pharmacological reports 66 (4), 534-544, 2014 | 263 | 2014 |
Serotonin receptors in depression and anxiety: Insights from animal studies E Żmudzka, K Sałaciak, J Sapa, K Pytka Life sciences 210, 106-124, 2018 | 181 | 2018 |
The role of serotonergic, adrenergic and dopaminergic receptors in antidepressant-like effect K Pytka, K Podkowa, A Rapacz, A Podkowa, E Żmudzka, A Olczyk, J Sapa, ... Pharmacological Reports 68 (2), 263-274, 2016 | 102 | 2016 |
The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect K Pytka, A Dziubina, K Młyniec, A Dziedziczak, E Żmudzka, A Furgała, ... Pharmacological Reports 68 (2), 443-450, 2016 | 72 | 2016 |
Synthesis and evaluation of antidepressant‐like activity of some 4‐substituted 1‐(2‐methoxyphenyl) piperazine derivatives AM Waszkielewicz, K Pytka, A Rapacz, E Wełna, M Jarzyna, G Satała, ... Chemical Biology & Drug Design 85 (3), 326-335, 2015 | 58 | 2015 |
Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT1A and 5-HT7 Antagonists in Animal Models K Pytka, A Partyka, M Jastrzębska-Więsek, A Siwek, M Głuch-Lutwin, ... PLoS One 10 (11), e0142499, 2015 | 50 | 2015 |
Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety AM Waszkielewicz, A Gunia, N Szkaradek, K Pytka, A Siwek, G Satała, ... Bioorganic & medicinal chemistry letters 23 (15), 4419-4423, 2013 | 45 | 2013 |
Synthesis and preliminary evaluation of pharmacological properties of some piperazine derivatives of xanthone N Szkaradek, A Rapacz, K Pytka, B Filipek, A Siwek, M Cegła, H Marona Bioorganic & medicinal chemistry 21 (2), 514-522, 2013 | 45 | 2013 |
Antidepressant-like activity of a new piperazine derivative of xanthone in the forced swim test in mice: The involvement of serotonergic system K Pytka, A Rapacz, M Zygmunt, A Olczyk, A Waszkielewicz, J Sapa, ... Pharmacological Reports 67 (1), 160-165, 2015 | 41 | 2015 |
A Comparison of the Anorectic Effect and Safety of the Alpha2-Adrenoceptor Ligands Guanfacine and Yohimbine in Rats with Diet-Induced Obesity M Dudek, J Knutelska, M Bednarski, L Nowiński, M Zygmunt, B Mordyl, ... Plos one 10 (10), e0141327, 2015 | 39 | 2015 |
Single Administration of HBK-15—a Triple 5-HT1A, 5-HT7, and 5-HT3 Receptor Antagonist—Reverses Depressive-Like Behaviors in Mouse Model of Depression … K Pytka, M Głuch-Lutwin, M Kotańska, A Waszkielewicz, A Kij, M Walczak Molecular Neurobiology 55, 3931-3945, 2018 | 38 | 2018 |
Revisiting the sigma-1 receptor as a biological target to treat affective and cognitive disorders K Sałaciak, K Pytka Neuroscience & Biobehavioral Reviews 132, 1114-1136, 2022 | 37 | 2022 |
The calcium/calmodulin-dependent kinases II and IV as therapeutic targets in neurodegenerative and neuropsychiatric disorders K Sałaciak, A Koszałka, E Żmudzka, K Pytka International Journal of Molecular Sciences 22 (9), 4307, 2021 | 33 | 2021 |
Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity A Bucki, M Marcinkowska, J Sniecikowska, K Wieckowski, M Pawłowski, ... Journal of Medicinal Chemistry 60 (17), 7483-7501, 2017 | 31 | 2017 |
The antidepressant-and anxiolytic-like activities of new xanthone derivative with piperazine moiety in behavioral tests in mice K Pytka, E Żmudzka, K Lustyk, A Rapacz, A Olczyk, A Gałuszka, ... Indian journal of pharmacology 48 (3), 286-291, 2016 | 30 | 2016 |
Novel aryloxyethyl derivatives of 1-(1-benzoylpiperidin-4-yl) methanamine as the extracellular regulated kinases 1/2 (ERK1/2) phosphorylation-preferring serotonin 5-HT1A … J Sniecikowska, M Gluch-Lutwin, A Bucki, A Wieckowska, A Siwek, ... Journal of Medicinal Chemistry 62 (5), 2750-2771, 2019 | 29 | 2019 |
H3 histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice M Dudek, K Kuder, M Kołaczkowski, A Olczyk, E Żmudzka, A Rak, ... Metabolic Brain Disease 31, 1023-1029, 2016 | 28 | 2016 |
The antidepressant-like activity of 6-methoxy-2-[4-(2-methoxyphenyl) piperazin-1-yl]-9H-xanthen-9-one involves serotonergic 5-HT1A and 5-HT2A/C receptors activation K Pytka, M Walczak, A Kij, A Rapacz, A Siwek, G Kazek, A Olczyk, ... European Journal of Pharmacology 764, 537-546, 2015 | 28 | 2015 |
Biased agonism in drug discovery: Is there a future for biased 5-HT1A receptor agonists in the treatment of neuropsychiatric diseases? K Sałaciak, K Pytka Pharmacology & Therapeutics 227, 107872, 2021 | 24 | 2021 |
HBK-15 protects mice from stress-induced behavioral disturbances and changes in corticosterone, BDNF, and NGF levels K Pytka, M Głuch-Lutwin, M Kotańska, E Żmudzka, M Jakubczyk, ... Behavioural Brain Research 333, 54-66, 2017 | 24 | 2017 |