| Distinct functions of AKT isoforms in breast cancer: a comprehensive review N Hinz, M Jücker Cell Communication and Signaling 17, 1-29, 2019 | 293 | 2019 |
| PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer FE Marquard, M Jücker Biochemical pharmacology 172, 113729, 2020 | 218 | 2020 |
| The role of mTOR signaling as a therapeutic target in cancer NV Popova, M Jücker International Journal of Molecular Sciences 22 (4), 1743, 2021 | 186 | 2021 |
| Expression of a mutated form of the p85α regulatory subunit of phosphatidylinositol 3-kinase in a Hodgkin's lymphoma-derived cell line (CO) M Jücker, K Südel, S Horn, M Sickel, W Wegner, W Fiedler, RA Feldman Leukemia 16 (5), 894-901, 2002 | 134 | 2002 |
| The Met/hepatocyte growth factor receptor (HGFR) gene is overexpressed in some cases of human leukemia and lymphoma M Jücker, A Günther, G Gradl, C Fonatsch, G Krueger, V Diehl, H Tesch Leukemia research 18 (1), 7-16, 1994 | 133 | 1994 |
| COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer BT Hofmann, L Schlüter, P Lange, B Mercanoglu, F Ewald, A Fölster, ... Molecular cancer 14 (1), 1-15, 2015 | 131 | 2015 |
| Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells N Grabinski, F Ewald, BT Hofmann, K Staufer, U Schumacher, B Nashan, ... Molecular cancer 11 (1), 1-14, 2012 | 128 | 2012 |
| Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic … J Wellbrock, E Latuske, J Köhler, K Wagner, H Stamm, E Vettorazzi, ... Clinical cancer research 21 (10), 2388-2398, 2015 | 115 | 2015 |
| The functional role of extracellular matrix proteins in cancer NV Popova, M Jücker Cancers 14 (1), 238, 2022 | 104 | 2022 |
| Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity C Koch, A Kuske, SA Joosse, G Yigit, G Sflomos, S Thaler, DJ Smit, ... EMBO molecular medicine 12 (9), e11908, 2020 | 104 | 2020 |
| Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells N Grabinski, K Bartkowiak, K Grupp, B Brandt, K Pantel, M Jücker Cellular signalling 23 (12), 1952-1960, 2011 | 96 | 2011 |
| Combined targeting of AKT and mTOR using MK‐2206 and RAD001 is synergistic in the treatment of cholangiocarcinoma F Ewald, N Grabinski, A Grottke, S Windhorst, D Nörz, L Carstensen, ... International journal of cancer 133 (9), 2065-2076, 2013 | 93 | 2013 |
| Tight junction proteins claudin-1 and occludin are important for cutaneous wound healing T Volksdorf, J Heilmann, SA Eming, K Schawjinski, M Zorn-Kruppa, ... The American journal of pathology 187 (6), 1301-1312, 2017 | 90 | 2017 |
| Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3β signaling and leads to an increased … S Horn, E Endl, B Fehse, MM Weck, GW Mayr, M Jücker Leukemia 18 (11), 1839-1849, 2004 | 88 | 2004 |
| Downregulation of AKT3 increases migration and metastasis in triple negative breast cancer cells by upregulating S100A4 A Grottke, F Ewald, T Lange, D Nörz, C Herzberger, J Bach, N Grabinski, ... PloS one 11 (1), e0146370, 2016 | 77 | 2016 |
| The role of PI3K/AKT/mTOR signaling in hepatocellular carcinoma metabolism LY Tian, DJ Smit, M Jücker International Journal of Molecular Sciences 24 (3), 2652, 2023 | 72 | 2023 |
| Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells S Horn, U Bergholz, M Jücker, JA McCubrey, L Trümper, C Stocking, ... Oncogene 27 (29), 4096-4106, 2008 | 68 | 2008 |
| Dual Inhibition of PI3K-AKT-mTOR-and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors F Ewald, D Nörz, A Grottke, BT Hofmann, B Nashan, M Jücker Investigational new drugs 32, 1144-1154, 2014 | 64 | 2014 |
| ErbB2 signaling activates the Hedgehog pathway via PI3K–Akt in human esophageal adenocarcinoma: Identification of novel targets for concerted therapy concepts M Kebenko, A Drenckhan, SJ Gros, M Jücker, N Grabinski, F Ewald, ... Cellular signalling 27 (2), 373-381, 2015 | 57 | 2015 |
| Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid–induced 2 S Werner, B Brors, J Eick, E Marques, V Pogenberg, A Parret, D Kemming, ... Cancer discovery 5 (5), 506-519, 2015 | 56 | 2015 |
