Genomic hallmarks and structural variation in metastatic prostate cancer DA Quigley, HX Dang, SG Zhao, P Lloyd, R Aggarwal, JJ Alumkal, A Foye, ... Cell 174 (3), 758-769. e9, 2018 | 648 | 2018 |
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells C Kücük, B Jiang, X Hu, W Zhang, JKC Chan, W Xiao, N Lack, C Alkan, ... Nature communications 6 (1), 6025, 2015 | 413 | 2015 |
Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening. NA Lack, P Axerio-Cilies, P Tavassoli, FQ Han, KH Chan, C Feau, ... Journal of medicinal chemistry 54 (24), 8563-8573, 2011 | 186 | 2011 |
A CD74-dependent MHC class I endolysosomal cross-presentation pathway G Basha, K Omilusik, A Chavez-Steenbock, AT Reinicke, N Lack, KB Choi, ... Nature immunology 13 (3), 237-245, 2012 | 182 | 2012 |
ARv7 represses tumor-suppressor genes in castration-resistant prostate cancer L Cato, J de Tribolet-Hardy, I Lee, JT Rottenberg, I Coleman, D Melchers, ... Cancer cell 35 (3), 401-413. e6, 2019 | 157 | 2019 |
Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms E Sim, N Lack, CJ Wang, H Long, I Westwood, E Fullam, A Kawamura Toxicology 254 (3), 170-183, 2008 | 155 | 2008 |
Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism NA Lack, KC Yam, ED Lowe, GP Horsman, RL Owen, E Sim, LD Eltis Journal of biological chemistry 285 (1), 434-443, 2010 | 117 | 2010 |
Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening P Axerio-Cilies, NA Lack, MRS Nayana, KH Chan, A Yeung, E Leblanc, ... Journal of medicinal chemistry 54 (18), 6197-6205, 2011 | 109 | 2011 |
Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer C Herberts, M Annala, J Sipola, SWS Ng, XE Chen, A Nurminen, ... Nature 608 (7921), 199-208, 2022 | 99 | 2022 |
Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole … RSN Munuganti, E Leblanc, P Axerio-Cilies, C Labriere, K Frewin, ... Journal of medicinal chemistry 56 (3), 1136-1148, 2013 | 98 | 2013 |
A Pharmacokinetic‐pharmacodynamic Model for the Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100 NA Lack, B Green, DC Dale, GB Calandra, H Lee, RT MacFarland, ... Clinical Pharmacology & Therapeutics 77 (5), 427-436, 2005 | 98 | 2005 |
Multiple routes of complement activation by Mycobacterium bovis BCG MV Carroll, N Lack, E Sim, A Krarup, RB Sim Molecular immunology 46 (16), 3367-3378, 2009 | 97 | 2009 |
Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis Y Zhang, JL Donaher, S Das, X Li, F Reinhardt, JA Krall, AW Lambert, ... Nature cell biology 24 (4), 554-564, 2022 | 62 | 2022 |
Androgen receptor-binding sites are highly mutated in prostate cancer T Morova, DR McNeill, N Lallous, M Gönen, K Dalal, DM Wilson III, ... Nature communications 11 (1), 832, 2020 | 55 | 2020 |
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway P Fineran, E Lloyd-Evans, NA Lack, N Platt, LC Davis, AJ Morgan, ... Wellcome open research 1, 2016 | 52 | 2016 |
Arylamine N-acetyltransferases in mycobacteria E Sim, J Sandy, D Evangelopoulos, E Fullam, S Bhakta, I Westwood, ... Current Drug Metabolism 9 (6), 510-519, 2008 | 52 | 2008 |
Androgen receptor plasticity and its implications for prostate cancer therapy O Snow, N Lallous, K Singh, N Lack, P Rennie, A Cherkasov Cancer treatment reviews 81, 101871, 2019 | 51 | 2019 |
Impact of the ST101 clone on fatality among patients with colistin-resistant Klebsiella pneumoniae infection F Can, S Menekse, P Ispir, N Atac, O Albayrak, T Demir, DC Karaaslan, ... Journal of Antimicrobial Chemotherapy 73 (5), 1235-1241, 2018 | 51 | 2018 |
Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis NA Lack, A Kawamura, E Fullam, N Laurieri, S Beard, AJ Russell, ... Biochemical Journal 418 (2), 369-378, 2009 | 50 | 2009 |
Genetic variants of MARCO are associated with susceptibility to pulmonary tuberculosis in a Gambian population DME Bowdish, K Sakamoto, NA Lack, PC Hill, G Sirugo, MJ Newport, ... BMC medical genetics 14, 1-7, 2013 | 48 | 2013 |