Physiological‐based pharmacokinetic modeling trends in pharmaceutical drug development over the last 20‐years; in‐depth analysis of applications, organizations, and platforms E El‐Khateeb, S Burkhill, S Murby, H Amirat, A Rostami‐Hodjegan, ... Biopharmaceutics & Drug Disposition 42 (4), 107-117, 2021 | 84 | 2021 |
Non-uniformity of changes in drug-metabolizing enzymes and transporters in liver cirrhosis: implications for drug dosage adjustment E El-Khateeb, B Achour, ZM Al-Majdoub, J Barber, A Rostami-Hodjegan Molecular pharmaceutics 18 (9), 3563-3577, 2021 | 40 | 2021 |
Effects of three different fibrates on intrahepatic cholestasis experimentally induced in rats A El-Sisi, S Hegazy, E El-Khateeb PPAR research 2013 (1), 781348, 2013 | 35 | 2013 |
time to revisit Child‐Pugh score as the basis for predicting drug clearance in hepatic impairment E El‐Khateeb, AS Darwich, B Achour, V Athwal, A Rostami‐Hodjegan Alimentary Pharmacology & Therapeutics 54 (4), 388-401, 2021 | 29 | 2021 |
Pharmacokinetics under the COVID‐19 storm V Pilla Reddy, E El‐Khateeb, H Jo, N Giovino, E Lythgoe, S Sharma, ... British Journal of Clinical Pharmacology 89 (1), 158-186, 2020 | 26 | 2020 |
Mass Spectrometry‐Based Abundance Atlas of ABC Transporters in Human Liver, Gut, Kidney, Brain, and Skin JB Zubida M. Al‐Majdoub, Brahim Achour, Narciso Couto, Martyn Howard ... FEBS letters, 2020 | 25 | 2020 |
Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: applications in translational pharmacology and recommendations for best practice E El-Khateeb, AM Vasilogianni, S Alrubia, ZM Al-Majdoub, N Couto, ... Pharmacology & Therapeutics 203, 107397, 2019 | 22 | 2019 |
Scaling factors for clearance in adult liver cirrhosis E El-Khateeb, B Achour, D Scotcher, ZM Al-Majdoub, V Athwal, J Barber, ... Drug Metabolism and Disposition 48 (12), 1271-1282, 2020 | 18 | 2020 |
Proteomic quantification of changes in abundance of drug-metabolizing enzymes and drug transporters in human liver cirrhosis: different methods, similar outcomes E El-Khateeb, ZM Al-Majdoub, A Rostami-Hodjegan, J Barber, B Achour Drug Metabolism and Disposition 49 (8), 610-618, 2021 | 17 | 2021 |
Bioanalytical strategies in drug discovery and development A Thakur, Z Tan, T Kameyama, E El-Khateeb, S Nagpal, S Malone, ... Drug Metabolism Reviews 53 (3), 434-458, 2021 | 13 | 2021 |
Proteomic quantification of perturbation to pharmacokinetic target proteins in liver disease AM Vasilogianni, E El-Khateeb, ZM Al-Majdoub, S Alrubia, ... Journal of Proteomics 263, 104601, 2022 | 9 | 2022 |
A randomized placebo-controlled, double-blind study to investigate the effect of a high oral loading dose of cholecalciferol in non-alcoholic fatty liver disease patients, new … SJ Alarfaj, MM Bahaa, HA Yassin, E El-Khateeb, FA Kotkata, ... European Review for Medical & Pharmacological Sciences 27 (16), 2023 | 4 | 2023 |
A family of QconCATs (Quantification conCATemers) for the quantification of human pharmacological target proteins AM Vasilogianni, E El-Khateeb, B Achour, S Alrubia, A Rostami-Hodjegan, ... Journal of Proteomics 261, 104572, 2022 | 4 | 2022 |
Evaluating the safety and efficacy of the leukotriene receptor antagonist montelukast as adjuvant therapy in obese patients with type 2 diabetes mellitus: A double-blind … E El-Khateeb, EI El-Berri, EM Mosalam, MZ Nooh, S Abdelsattar, ... Frontiers in Pharmacology 14, 1153653, 2023 | 3 | 2023 |
The potential therapeutic effect of metformin in type 2 diabetic patients with severe COVID-19. HM Al-Kuraishy, AI Al-Gareeb, AA El Kholy, E El-Khateeb, A Alexiou, ... European Review for Medical & Pharmacological Sciences 27 (23), 2023 | 2 | 2023 |
Using Prior Knowledge on Systems Through PBPK to Gain Further Insight into Routine Clinical Data on Trough Concentrations: The Case of Tacrolimus in Chronic Kidney Disease E El-Khateeb, R Chinnadurai, J Al Qassabi, D Scotcher, AS Darwich, ... Therapeutic Drug Monitoring, 10.1097, 2022 | 1 | 2022 |
Complementarity of two proteomic data analysis tools in the identification of drug-metabolising enzymes and transporters in human liver AM Vasilogianni, S Alrubia, E El-Khateeb, ZM Al-Majdoub, N Couto, ... Molecular Omics, 2024 | | 2024 |
Randomized Clinical and Biochemical Study Comparing the Effect of L-arginine and Sildenafil in Beta Thalassemia Major Children With High Tricuspid Regurgitant Jet Velocity E El-Khateeb, SM El-Haggar, O El-Razaky, MR El-Shanshory, TM Mostafa Journal of Cardiovascular Pharmacology and Therapeutics 27, 10742484221132671, 2022 | | 2022 |
Optimising Translational Aspects of Physiologically-Based Pharmacokinetic Modelling and Simulation to Aid Precision Dosing in Liver Cirrhosis EM El-Khateeb PQDT-UK & Ireland, 2021 | | 2021 |
PBPK in liver cirrhosis population E Elkhateeb Utilising PBPK modeling and simulations in precision dosing in cirrhosis …, 2019 | | 2019 |