An epithelial–mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor … LA Byers, L Diao, J Wang, P Saintigny, L Girard, M Peyton, L Shen, Y Fan, ... Clinical cancer research 19 (1), 279-290, 2013 | 1022 | 2013 |
Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. SB Kanner, AB Reynolds, RR Vines, JT Parsons Proceedings of the National Academy of Sciences 87 (9), 3328-3332, 1990 | 641 | 1990 |
A role for CD5 in TCR-mediated signal transduction and thymocyte selection A Tarakhovsky, SB Kanner, J Hombach, JA Ledbetter, W Müller, N Killeen, ... Science 269 (5223), 535-537, 1995 | 549 | 1995 |
Identification and Characterization of a Novel Cytoskeleton-Associated pp60src Substrate H Wu, AB Reynolds, SB Kanner, RR Vines, JT Parsons Molecular and cellular biology 11 (10), 5113-5124, 1991 | 549 | 1991 |
RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg CI Wooddell, MF Yuen, HLY Chan, RG Gish, SA Locarnini, D Chavez, ... Science translational medicine 9 (409), eaan0241, 2017 | 446 | 2017 |
Transformation-Specific Tyrosine Phosphorylation of a Novel Cellular Protein in Chicken Cells Expressing Oncogenic Variants of the Avian Cellular src Gene AB Reynolds, DJ Roesel, SB Kanner, JT Parsons Molecular and cellular biology 9 (2), 629-638, 1989 | 446 | 1989 |
Wiskott-Aldrich syndrome/X-linked thrombocytopenia: WASP gene mutations, protein expression, and phenotype Q Zhu, C Watanabe, T Liu, D Hollenbaugh, RM Blaese, SB Kanner, ... Blood, The Journal of the American Society of Hematology 90 (7), 2680-2689, 1997 | 346 | 1997 |
The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110. SB Kanner, AB Reynolds, HC Wang, RR Vines, JT Parsons The EMBO Journal 10 (7), 1689-1698, 1991 | 266 | 1991 |
Filamin binds to the cytoplasmic domain of the β1-integrin: identification of amino acids responsible for this interaction DT Loo, SB Kanner, A Aruffo Journal of Biological Chemistry 273 (36), 23304-23312, 1998 | 262 | 1998 |
CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1 JJ Perez-Villar, GS Whitney, MA Bowen, DH Hewgill, AA Aruffo, ... Molecular and cellular biology, 1999 | 260 | 1999 |
Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation. SB Kanner, LS Grosmaire, JA Ledbetter, NK Damle Proceedings of the National Academy of Sciences 90 (15), 7099-7103, 1993 | 249 | 1993 |
Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins AB Reynolds, SB Kanner, HCR Wang, JT Parsons Molecular and cellular biology, 1989 | 230 | 1989 |
ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV-and H2O2-induced T cell signal transduction. GL Schieven, RS Mittler, SG Nadler, JM Kirihara, JB Bolen, SB Kanner, ... Journal of Biological Chemistry 269 (32), 20718-20726, 1994 | 188 | 1994 |
Epigenetic drug discovery: targeting DNA methyltransferases JM Foulks, KM Parnell, RN Nix, S Chau, K Swierczek, M Saunders, ... Journal of biomolecular screening 17 (1), 2-17, 2012 | 184 | 2012 |
A 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in … CM Ely, KM Oddie, JS Litz, AJ Rossomando, SB Kanner, TW Sturgill, ... The Journal of cell biology 110 (3), 731-742, 1990 | 167 | 1990 |
A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK. PY Chan, SB Kanner, G Whitney, A Aruffo Journal of Biological Chemistry 269 (32), 20567-20574, 1994 | 161 | 1994 |
Tyrosine Phosphorylation of a 120-Kilodalton pp60src Substrate upon Epidermal Growth Factor and Platelet-Derived Growth Factor Receptor Stimulation and in … SB Kanner, AB Reynolds, JT Parsons Molecular and cellular biology 11 (2), 713-720, 1991 | 161 | 1991 |
Monoclonal antibodies to six-transmembrane epithelial antigen of the prostate-1 inhibit intercellular communication in vitro and growth of human tumor xenografts in vivo PM Challita-Eid, K Morrison, S Etessami, Z An, KJ Morrison, ... Cancer research 67 (12), 5798-5805, 2007 | 158 | 2007 |
Selective Itk inhibitors block T-cell activation and murine lung inflammation TA Lin, KW McIntyre, J Das, C Liu, KD O'Day, B Penhallow, CY Hung, ... Biochemistry 43 (34), 11056-11062, 2004 | 141 | 2004 |
Human T and B Lymphocytes Express a Structurally Conserved Focal Adhesion Kinase, pp125FAK GS WHITNEY, POY CHAN, J BLAKE, WL COSAND, MG NEUBAUER, ... DNA and cell biology 12 (9), 823-830, 1993 | 135 | 1993 |