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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery DH Kim, DD Sarbassov, SM Ali, JE King, RR Latek, ... Cell 110 (2), 163-175, 2002 | 3724 | 2002 |
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton DD Sarbassov, SM Ali, DH Kim, DA Guertin, RR Latek, ... Current biology 14 (14), 1296-1302, 2004 | 3421 | 2004 |
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB DD Sarbassov, SM Ali, S Sengupta, JH Sheen, PP Hsu, AF Bagley, ... Molecular cell 22 (2), 159-168, 2006 | 3289 | 2006 |
Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden ZR Chalmers, CF Connelly, D Fabrizio, L Gay, SM Ali, R Ennis, A Schrock, ... Genome medicine 9, 1-14, 2017 | 2981 | 2017 |
Growing roles for the mTOR pathway DD Sarbassov, SM Ali, DM Sabatini Current opinion in cell biology 17 (6), 596-603, 2005 | 2013 | 2005 |
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ... Cancer discovery 8 (7), 822-835, 2018 | 1282 | 2018 |
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Calcineurin associated with the inositol 1, 4, 5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux AM Cameron, JP Steiner, AJ Roskams, SM Ali, GV Ronnettt, SH Snyder Cell 83 (3), 463-472, 1995 | 613 | 1995 |
Pembrolizumab as neoadjuvant therapy before radical cystectomy in patients with muscle-invasive urothelial bladder carcinoma (PURE-01): an open-label, single-arm, phase II study A Necchi, A Anichini, D Raggi, A Briganti, S Massa, R Lucianò, ... Journal of Clinical Oncology 36 (34), 3353-3360, 2018 | 608 | 2018 |
Tumor mutational burden is predictive of response to immune checkpoint inhibitors in MSI-high metastatic colorectal cancer AB Schrock, C Ouyang, J Sandhu, E Sokol, D Jin, JS Ross, VA Miller, ... Annals of Oncology 30 (7), 1096-1103, 2019 | 575 | 2019 |
New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing JS Ross, K Wang, L Gay, R Al-Rohil, JV Rand, DM Jones, HJ Lee, ... The oncologist 19 (3), 235-242, 2014 | 496 | 2014 |
Targeted next generation sequencing identifies markers of response to PD-1 blockade DB Johnson, GM Frampton, MJ Rioth, E Yusko, Y Xu, X Guo, RC Ennis, ... Cancer immunology research 4 (11), 959-967, 2016 | 471 | 2016 |
Diverse and targetable kinase alterations drive histiocytic neoplasms EL Diamond, BH Durham, J Haroche, Z Yao, J Ma, SA Parikh, Z Wang, ... Cancer discovery 6 (2), 154-165, 2016 | 463 | 2016 |
Characterization of 298 patients with lung cancer harboring MET exon 14 skipping alterations AB Schrock, GM Frampton, J Suh, ZR Chalmers, M Rosenzweig, ... Journal of Thoracic Oncology 11 (9), 1493-1502, 2016 | 390 | 2016 |
Biliary cancer: utility of next‐generation sequencing for clinical management M Javle, T Bekaii‐Saab, A Jain, Y Wang, RK Kelley, K Wang, HC Kang, ... Cancer 122 (24), 3838-3847, 2016 | 370 | 2016 |
Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer JM Mehnert, A Panda, H Zhong, K Hirshfield, S Damare, K Lane, L Sokol, ... The Journal of clinical investigation 126 (6), 2334-2340, 2016 | 370 | 2016 |
Open-Label, Multicenter, Phase II Study of Ceritinib in Patients With Non–Small-Cell Lung Cancer Harboring ROS1 Rearrangement SM Lim, HR Kim, JS Lee, KH Lee, YG Lee, YJ Min, EK Cho, SS Lee, ... Journal of clinical oncology 35 (23), 2613-2618, 2017 | 354 | 2017 |
Non-V600BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer JC Jones, LA Renfro, HO Al-Shamsi, AB Schrock, A Rankin, BY Zhang, ... Journal of Clinical Oncology 35 (23), 2624-2630, 2017 | 352 | 2017 |