Neuronal and cardiovascular potassium channels as therapeutic drug targets: promise and pitfalls ESA Humphries, C Dart Journal of biomolecular screening 20 (9), 1055-1073, 2015 | 120 | 2015 |
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells J Kramer, HM Himmel, A Lindqvist, S Stoelzle-Feix, KW Chaudhary, D Li, ... Scientific reports 10 (1), 5627, 2020 | 46 | 2020 |
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ... Toxicology and Applied Pharmacology 394, 114961, 2020 | 40 | 2020 |
The effect of low pH in erosion-corrosion resistance of high chromium cast irons and stainless steels G Karafyllias, A Galloway, E Humphries Wear 420, 79-86, 2019 | 34 | 2019 |
Calcium/calmodulin‐dependent kinase 2 mediates Epac‐induced spontaneous transient outward currents in rat vascular smooth muscle ESA Humphries, T Kamishima, JM Quayle, C Dart The Journal of Physiology 595 (18), 6147-6164, 2017 | 18 | 2017 |
(W1‐x,Mx)C carbides with desired combinations of compatible density and properties – A first‐principles study R Liu, D Zhang, Y Tang, X Tang, E Humphries, D Li Journal of the American Ceramic Society 104 (8), 4239-4256, 2021 | 13 | 2021 |
There is no F in APC: using physiological fluoride-free solutions for high throughput automated patch clamp experiments M Rapedius, A Obergrussberger, ESA Humphries, S Scholz, ... Frontiers in Molecular Neuroscience 15, 982316, 2022 | 11 | 2022 |
Erosion-corrosion assessment in strong acidic conditions for a white cast iron and UNS S31600 stainless steel G Karafyllias, A Galloway, E Humphries Wear 484, 203665, 2021 | 11 | 2021 |
Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts PC Poulsen, M Schrölkamp, N Bagwan, U Leurs, ESA Humphries, ... Journal of Molecular and Cellular Cardiology 143, 63-70, 2020 | 10 | 2020 |
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells J Kramer, HM Himmel, A Lindqvist, S Stoelzle-Feix, KW Chaudhary, D Li, ... Scientific reports 10, 2020 | 3 | 2020 |
V-substituted Ti1-xVxC carbides in comparison with Mono-TiC carbide–A study combining first-principle calculations and experiments D Zhang, XH Tang, E Humphries, DY Li Wear 523, 204808, 2023 | 2 | 2023 |
Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm”[Toxicology and Applied Pharmacology volume 394C … BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ... Toxicology and Applied Pharmacology 395, 2020 | 2 | 2020 |
Erosion-corrosion evaluation of two white cast irons under severe conditions for application in the oil sands industry G Karafyllias, E Humphries, A Galloway NACE CORROSION, NACE-2018-11405, 2018 | 1 | 2018 |
Development of an impedance based screening assay for cardiac safety and cardiotoxicity detection R Kirby, S El Haou, E Humphries, J Ridley, M Rogers Journal of Pharmacological and Toxicological Methods 105, 106849, 2020 | | 2020 |
Predicting proarrhythmic risk exclusively using automated patch clamp data E Humphries, J Ridley, R Kirby, M Rogers Journal of Pharmacological and Toxicological Methods 105, 106728, 2020 | | 2020 |
Using new in vitro cardiac ion channel assays and in silico models to predict proarrhythmic risk with automated patch clamp data ES Humphries, J Ridley, RW Kirby, M Rogers Biophysical Journal 118 (3), 591a, 2020 | | 2020 |
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm R Bardenet, BJ Ridder, DJ Leishman, M Bridgland-Taylor, ... Toxicology and Applied Pharmacology 394, 2020 | | 2020 |
New CiPA cardiac ion channel cell lines and assays for in vitro proarrhythmia risk assessment ESA Humphries, RW Kirby, L Webdale, M Rogers Journal of Pharmacological and Toxicological Methods 99, 2019 | | 2019 |
Exchange Protein directly Activated by cAMP (Epac) in the vasculature ESA Humphries PQDT-Global, 2017 | | 2017 |
Epac‐mediated Vasorelaxation: Epac Increases Spontaneous Transient Outward Current (STOC) In Mesenteric Artery Smooth Muscle Via Activation Of CAMKII C Dart, ESA Humphries The FASEB Journal 30, 969.24-969.24, 2016 | | 2016 |