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Edward Humphries
Edward Humphries
Metrion Biosciences
在 metrionbiosciences.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Neuronal and cardiovascular potassium channels as therapeutic drug targets: promise and pitfalls
ESA Humphries, C Dart
Journal of biomolecular screening 20 (9), 1055-1073, 2015
1202015
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
J Kramer, HM Himmel, A Lindqvist, S Stoelzle-Feix, KW Chaudhary, D Li, ...
Scientific reports 10 (1), 5627, 2020
462020
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm
BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ...
Toxicology and Applied Pharmacology 394, 114961, 2020
402020
The effect of low pH in erosion-corrosion resistance of high chromium cast irons and stainless steels
G Karafyllias, A Galloway, E Humphries
Wear 420, 79-86, 2019
342019
Calcium/calmodulin‐dependent kinase 2 mediates Epac‐induced spontaneous transient outward currents in rat vascular smooth muscle
ESA Humphries, T Kamishima, JM Quayle, C Dart
The Journal of Physiology 595 (18), 6147-6164, 2017
182017
(W1‐x,Mx)C carbides with desired combinations of compatible density and properties – A first‐principles study
R Liu, D Zhang, Y Tang, X Tang, E Humphries, D Li
Journal of the American Ceramic Society 104 (8), 4239-4256, 2021
132021
There is no F in APC: using physiological fluoride-free solutions for high throughput automated patch clamp experiments
M Rapedius, A Obergrussberger, ESA Humphries, S Scholz, ...
Frontiers in Molecular Neuroscience 15, 982316, 2022
112022
Erosion-corrosion assessment in strong acidic conditions for a white cast iron and UNS S31600 stainless steel
G Karafyllias, A Galloway, E Humphries
Wear 484, 203665, 2021
112021
Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts
PC Poulsen, M Schrölkamp, N Bagwan, U Leurs, ESA Humphries, ...
Journal of Molecular and Cellular Cardiology 143, 63-70, 2020
102020
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
J Kramer, HM Himmel, A Lindqvist, S Stoelzle-Feix, KW Chaudhary, D Li, ...
Scientific reports 10, 2020
32020
V-substituted Ti1-xVxC carbides in comparison with Mono-TiC carbide–A study combining first-principle calculations and experiments
D Zhang, XH Tang, E Humphries, DY Li
Wear 523, 204808, 2023
22023
Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm”[Toxicology and Applied Pharmacology volume 394C …
BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ...
Toxicology and Applied Pharmacology 395, 2020
22020
Erosion-corrosion evaluation of two white cast irons under severe conditions for application in the oil sands industry
G Karafyllias, E Humphries, A Galloway
NACE CORROSION, NACE-2018-11405, 2018
12018
Development of an impedance based screening assay for cardiac safety and cardiotoxicity detection
R Kirby, S El Haou, E Humphries, J Ridley, M Rogers
Journal of Pharmacological and Toxicological Methods 105, 106849, 2020
2020
Predicting proarrhythmic risk exclusively using automated patch clamp data
E Humphries, J Ridley, R Kirby, M Rogers
Journal of Pharmacological and Toxicological Methods 105, 106728, 2020
2020
Using new in vitro cardiac ion channel assays and in silico models to predict proarrhythmic risk with automated patch clamp data
ES Humphries, J Ridley, RW Kirby, M Rogers
Biophysical Journal 118 (3), 591a, 2020
2020
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm
R Bardenet, BJ Ridder, DJ Leishman, M Bridgland-Taylor, ...
Toxicology and Applied Pharmacology 394, 2020
2020
New CiPA cardiac ion channel cell lines and assays for in vitro proarrhythmia risk assessment
ESA Humphries, RW Kirby, L Webdale, M Rogers
Journal of Pharmacological and Toxicological Methods 99, 2019
2019
Exchange Protein directly Activated by cAMP (Epac) in the vasculature
ESA Humphries
PQDT-Global, 2017
2017
Epac‐mediated Vasorelaxation: Epac Increases Spontaneous Transient Outward Current (STOC) In Mesenteric Artery Smooth Muscle Via Activation Of CAMKII
C Dart, ESA Humphries
The FASEB Journal 30, 969.24-969.24, 2016
2016
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