Selective inhibition of lysine‐specific demethylase 5A (KDM5A) using a rhodium (III) complex for triple‐negative breast cancer therapy GJ Yang, W Wang, SWF Mok, C Wu, BYK Law, XM Miao, KJ Wu, ... Angewandte Chemie 130 (40), 13275-13279, 2018 | 145 | 2018 |
A small molecule HIF-1α stabilizer that accelerates diabetic wound healing G Li, CN Ko, D Li, C Yang, W Wang, GJ Yang, C Di Primo, VKW Wong, ... Nature communications 12 (1), 3363, 2021 | 129 | 2021 |
Pharmacological inhibition of LSD1 for cancer treatment GJ Yang, PM Lei, SY Wong, DL Ma, CH Leung Molecules 23 (12), 3194, 2018 | 122 | 2018 |
Recent development of transition metal complexes with in vivo antitumor activity JX Liang, HJ Zhong, G Yang, K Vellaisamy, DL Ma, CH Leung Journal of Inorganic Biochemistry 177, 276-286, 2017 | 107 | 2017 |
The design and development of covalent protein-protein interaction inhibitors for cancer treatment SS Cheng, GJ Yang, W Wang, CH Leung, DL Ma Journal of hematology & oncology 13, 1-14, 2020 | 86 | 2020 |
The emerging role of KDM5A in human cancer GJ Yang, MH Zhu, XJ Lu, YJ Liu, JF Lu, CH Leung, DL Ma, J Chen Journal of hematology & oncology 14, 1-18, 2021 | 79 | 2021 |
Structure-based discovery of a selective KDM5A inhibitor that exhibits anti-cancer activity via inducing cell cycle arrest and senescence in breast cancer cell lines GJ Yang, CN Ko, HJ Zhong, CH Leung, DL Ma Cancers 11 (1), 92, 2019 | 70 | 2019 |
Identification of a rhodium (iii) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells GJ Yang, HJ Zhong, CN Ko, SY Wong, K Vellaisamy, M Ye, DL Ma, ... Chemical Communications 54 (20), 2463-2466, 2018 | 52 | 2018 |
Emerging Screening Approaches in the development of Nrf2–Keap1 protein–protein interaction inhibitors CH Leung, JT Zhang, GJ Yang, H Liu, QB Han, DL Ma International journal of molecular sciences 20 (18), 4445, 2019 | 51 | 2019 |
The application of a G-quadruplex based assay with an iridium (III) complex to arsenic ion detection and its utilization in a microfluidic chip S Lin, W Wang, C Hu, G Yang, CN Ko, K Ren, CH Leung, DL Ma Journal of Materials Chemistry B 5 (3), 479-484, 2017 | 51 | 2017 |
Molecular characterization and functional analysis of a novel C-type lectin receptor-like gene from a teleost fish, Plecoglossus altivelis GJ Yang, XJ Lu, Q Chen, J Chen Fish & shellfish immunology 44 (2), 603-610, 2015 | 43 | 2015 |
Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer SS Cheng, YQ Qu, J Wu, GJ Yang, H Liu, W Wang, Q Huang, F Chen, G Li, ... Acta Pharmaceutica Sinica B 12 (3), 1390-1405, 2022 | 42 | 2022 |
LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells XJ Lu, Q Chen, YJ Rong, GJ Yang, CH Li, NY Xu, CH Yu, HY Wang, ... Nature communications 7 (1), 12719, 2016 | 39 | 2016 |
Small Molecule Pin1 Inhibitor Blocking NF‐κB Signaling in Prostate Cancer Cells KJ Wu, HJ Zhong, G Yang, C Wu, JM Huang, G Li, DL Ma, CH Leung Chemistry–An Asian Journal 13 (3), 275-279, 2018 | 37 | 2018 |
An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells GJ Yang, YQ Song, W Wang, QB Han, DL Ma, CH Leung Bioorganic Chemistry 114, 105158, 2021 | 32 | 2021 |
Application of MOF-based nanotherapeutics in light-mediated cancer diagnosis and therapy D Zhao, W Zhang, S Yu, SL Xia, YN Liu, GJ Yang Journal of Nanobiotechnology 20 (1), 421, 2022 | 31 | 2022 |
Pharmacological inhibition of KDM5A for cancer treatment GJ Yang, J Wu, L Miao, MH Zhu, QJ Zhou, XJ Lu, JF Lu, CH Leung, ... European Journal of Medicinal Chemistry 226, 113855, 2021 | 31 | 2021 |
Rebalancing metal dyshomeostasis for Alzheimer’s disease therapy GJ Yang, H Liu, DL Ma, CH Leung JBIC Journal of Biological Inorganic Chemistry 24 (8), 1159-1170, 2019 | 29 | 2019 |
An aldol reaction-based Iridium (III) chemosensor for the visualization of proline in living cells JB Liu, LJ Liu, ZZ Dong, GJ Yang, CH Leung, DL Ma Scientific Reports 6 (1), 36509, 2016 | 28 | 2016 |
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative … S Cheng, GJ Yang, W Wang, DL Ma, CH Leung Genes & diseases 9 (6), 1674-1688, 2022 | 26 | 2022 |