Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab N Papadopoulos, J Martin, Q Ruan, A Rafique, MP Rosconi, E Shi, ... Angiogenesis 15, 171-185, 2012 | 1195 | 2012 |
Kyratsous CA J Hansen, A Baum, KE Pascal, V Russo, S Giordano, E Wloga, BO Fulton, ... Studies in humanized mice and convalescent humans yield a SARS-CoV-2 …, 2020 | 1062 | 2020 |
Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant L Yurkovetskiy, X Wang, KE Pascal, C Tomkins-Tinch, TP Nyalile, Y Wang, ... Cell 183 (3), 739-751. e8, 2020 | 1038 | 2020 |
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail J Hansen, A Baum, KE Pascal, V Russo, S Giordano, E Wloga, BO Fulton, ... Science 369 (6506), 1010-1014, 2020 | 989 | 2020 |
High affinity antibodies to human IL-6 receptor S Stevens, TT Huang, JH Martin, JL Fairhurst, A Rafique, E Smith, ... US Patent 7,582,298, 2009 | 441 | 2009 |
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering S Davis, N Papadopoulos, TH Aldrich, PC Maisonpierre, T Huang, ... Nature structural biology 10 (1), 38-44, 2003 | 327 | 2003 |
Dual blockade of IL‐4 and IL‐13 with dupilumab, an IL‐4Rα antibody, is required to broadly inhibit type 2 inflammation A Le Floc’h, J Allinne, K Nagashima, G Scott, D Birchard, S Asrat, Y Bai, ... Allergy 75 (5), 1188-1204, 2020 | 273 | 2020 |
ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys V Gusarova, CA Alexa, Y Wang, A Rafique, JH Kim, D Buckler, IJ Mintah, ... Journal of lipid research 56 (7), 1308-1317, 2015 | 211 | 2015 |
Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement JM Orengo, AR Radin, V Kamat, A Badithe, LH Ben, BL Bennett, S Zhong, ... Nature communications 9 (1), 1421, 2018 | 204 | 2018 |
Activin A more prominently regulates muscle mass in primates than does GDF8 E Latres, J Mastaitis, W Fury, L Miloscio, J Trejos, J Pangilinan, ... Nature communications 8 (1), 15153, 2017 | 166 | 2017 |
Development of clinical-stage human monoclonal antibodies that treat advanced Ebola virus disease in nonhuman primates KE Pascal, D Dudgeon, JC Trefry, M Anantpadma, Y Sakurai, CD Murin, ... The Journal of infectious diseases 218 (suppl_5), S612-S626, 2018 | 159 | 2018 |
Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice E Latres, J Pangilinan, L Miloscio, R Bauerlein, E Na, TB Potocky, ... Skeletal muscle 5, 1-13, 2015 | 142 | 2015 |
Characterization of the Anti–PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice E Burova, A Hermann, J Waite, T Potocky, V Lai, S Hong, M Liu, ... Molecular cancer therapeutics 16 (5), 861-870, 2017 | 141 | 2017 |
Bispecific antibodies and antibody–drug conjugates (ADCs) bridging HER2 and prolactin receptor improve efficacy of HER2 ADCs J Andreev, N Thambi, AE Perez Bay, F Delfino, J Martin, MP Kelly, ... Molecular cancer therapeutics 16 (4), 681-693, 2017 | 139 | 2017 |
A global benchmark study using affinity-based biosensors RL Rich, GA Papalia, PJ Flynn, J Furneisen, J Quinn, JS Klein, ... Analytical biochemistry 386 (2), 194-216, 2009 | 124 | 2009 |
High affinity human antibodies to human IL-4 receptor S Stevens, TT Huang, JH Martin, JL Fairhurst, A Rafique, M Torres, ... US Patent 7,605,237, 2009 | 122 | 2009 |
Designing binding kinetic assay on the bio-layer interferometry (BLI) biosensor to characterize antibody-antigen interactions V Kamat, A Rafique Analytical biochemistry 536, 16-31, 2017 | 109 | 2017 |
Comparative analyses of a small molecule/enzyme interaction by multiple users of Biacore technology MJ Cannon, GA Papalia, I Navratilova, RJ Fisher, LR Roberts, KM Worthy, ... Analytical biochemistry 330 (1), 98-113, 2004 | 102 | 2004 |
Glucagon receptor blockade with a human antibody normalizes blood glucose in diabetic mice and monkeys H Okamoto, J Kim, JP Aglione, J Lee, K Cavino, E Na, A Rafique, JH Kim, ... Endocrinology 156 (8), 2781-2794, 2015 | 96 | 2015 |
A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies D Skokos, JC Waite, L Haber, A Crawford, A Hermann, E Ullman, R Slim, ... Science translational medicine 12 (525), eaaw7888, 2020 | 89 | 2020 |