| Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis R Jackstadt, SR van Hooff, JD Leach, X Cortes-Lavaud, JO Lohuis, ... Cancer cell 36 (3), 319-336. e7, 2019 | 356 | 2019 |
| Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors P Kemmeren, K Sameith, LAL Van De Pasch, JJ Benschop, TL Lenstra, ... Cell 157 (3), 740-752, 2014 | 341 | 2014 |
| The specificity and topology of chromatin interaction pathways in yeast TL Lenstra, JJ Benschop, TS Kim, JM Schulze, NACH Brabers, ... Molecular cell 42 (4), 536-549, 2011 | 266 | 2011 |
| An endometrial gene expression signature accurately predicts recurrent implantation failure after IVF YEM Koot, SR Van Hooff, CM Boomsma, D Van Leenen, ... Scientific Reports 6 (1), 19411, 2016 | 196 | 2016 |
| Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models JF Linnekamp, SR Hooff, PR Prasetyanti, R Kandimalla, JY Buikhuisen, ... Cell Death & Differentiation 25 (3), 616-633, 2018 | 195 | 2018 |
| TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype E Fessler, J Drost, SR van Hooff, JF Linnekamp, X Wang, M Jansen, ... EMBO molecular medicine 8 (7), 745-760, 2016 | 162 | 2016 |
| Functional overlap and regulatory links shape genetic interactions between signaling pathways S van Wageningen, P Kemmeren, P Lijnzaad, T Margaritis, JJ Benschop, ... Cell 143 (6), 991-1004, 2010 | 152 | 2010 |
| Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3′-end antisense transcription T Margaritis, V Oreal, N Brabers, L Maestroni, A Vitaliano-Prunier, ... Public Library of Science 8 (9), e1002952, 2012 | 145 | 2012 |
| Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell G Kildisiute, WM Kholosy, MD Young, K Roberts, R Elmentaite, ... Science advances 7 (6), eabd3311, 2021 | 125 | 2021 |
| PDGFRB promotes liver metastasis formation of mesenchymal-like colorectal tumor cells EJA Steller, DA Raats, J Koster, B Rutten, KM Govaert, BL Emmink, ... Neoplasia 15 (2), 204-IN30, 2013 | 108 | 2013 |
| Validation of a gene expression signature for assessment of lymph node metastasis in oral squamous cell carcinoma SR Van Hooff, FKJ Leusink, P Roepman, RJ Baatenburg de Jong, ... Journal of clinical oncology 30 (33), 4104-4110, 2012 | 97 | 2012 |
| Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems F Dijk, VL Veenstra, EC Soer, MPG Dings, L Zhao, JB Halfwerk, ... Scientific reports 10 (1), 337, 2020 | 71 | 2020 |
| Novel diagnostic modalities for assessment of the clinically node-negative neck in oral squamous-cell carcinoma FKJ Leusink, RJJ van Es, R de Bree, RJB de Jong, SR van Hooff, ... The Lancet Oncology 13 (12), e554-e561, 2012 | 70 | 2012 |
| Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery S Di Franco, P Bianca, DS Sardina, A Turdo, M Gaggianesi, V Veschi, ... Nature communications 12 (1), 5006, 2021 | 62 | 2021 |
| A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype E Fessler, M Jansen, F De Sousa E Melo, L Zhao, PR Prasetyanti, ... Oncogene 35 (46), 6026-6037, 2016 | 61 | 2016 |
| Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis JDG Leach, N Vlahov, P Tsantoulis, RA Ridgway, DJ Flanagan, K Gilroy, ... Nature communications 12 (1), 3464, 2021 | 55 | 2021 |
| Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer N Snoeren, BL Emmink, MJG Koerkamp, SR van Hooff, JACM Goos, ... British journal of cancer 109 (6), 1636-1647, 2013 | 54 | 2013 |
| Adaptable gene‐specific dye bias correction for two‐channel DNA microarrays T Margaritis, P Lijnzaad, D Van Leenen, D Bouwmeester, P Kemmeren, ... Molecular Systems Biology 5 (1), 266, 2009 | 51 | 2009 |
| Neoadjuvant chemotherapy affects molecular classification of colorectal tumors K Trumpi, I Ubink, A Trinh, M Djafarihamedani, JM Jongen, KM Govaert, ... Oncogenesis 6 (7), e357-e357, 2017 | 46 | 2017 |
| Nodal metastasis and survival in oral cancer: Association with protein expression of SLPI, not with LCN2, TACSTD2, or THBS2 R Noorlag, P Van Der Groep, FKJ Leusink, SR Van Hooff, MH Frank, ... Head & neck 37 (8), 1130-1136, 2015 | 46 | 2015 |
