Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation MV Airola, P Shanbhogue, AA Shamseddine, KE Guja, CE Senkal, ... Proceedings of the National Academy of Sciences 114 (28), E5549-E5558, 2017 | 94 | 2017 |
Alternate splicing of dysferlin C2A confers Ca2+-dependent and Ca2+-independent binding for membrane repair K Fuson, A Rice, R Mahling, A Snow, K Nayak, P Shanbhogue, AG Meyer, ... Structure 22 (1), 104-115, 2014 | 62 | 2014 |
Exploring the therapeutic landscape of sphingomyelinases P Shanbhogue, YA Hannun Lipid Signaling in Human Diseases, 19-47, 2020 | 19 | 2020 |
The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme P Shanbhogue, RM Hoffmann, MV Airola, R Maini, DJ Hamelin, ... Journal of Biological Chemistry 294 (18), 7488-7502, 2019 | 15 | 2019 |
Bovine antibody variants CJ STRIETZEL, SAM LIGHTLE, HL CAMPOS, Y ZHU, G John FICI, ... WO Patent WO2022109313A1, 2022 | | 2022 |
Fragment-based de novo design targeting FABP5 and nSMase2 L Prentis, P Shanbhogue, Y Hannun, R Rizzo ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Crystal structure and activation mechanism of human neutral sphingomyelinase 2 P Shanbhogue, M Airola, A Shamseddine, K Guja, R Maini, N Bartke, ... The FASEB Journal 31, 781.8-781.8, 2017 | | 2017 |
On the forces stabilizing supertertiary structure in multi‐domain proteins (770.2) E Lemmon, P Shanbhogue, J McCann, M Bowen The FASEB Journal 28, 770.2, 2014 | | 2014 |