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Prajna Shanbhogue
Prajna Shanbhogue
Senior Principal Scientist, Zoetis Inc.
在 zoetis.com 的电子邮件经过验证
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Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation
MV Airola, P Shanbhogue, AA Shamseddine, KE Guja, CE Senkal, ...
Proceedings of the National Academy of Sciences 114 (28), E5549-E5558, 2017
942017
Alternate splicing of dysferlin C2A confers Ca2+-dependent and Ca2+-independent binding for membrane repair
K Fuson, A Rice, R Mahling, A Snow, K Nayak, P Shanbhogue, AG Meyer, ...
Structure 22 (1), 104-115, 2014
622014
Exploring the therapeutic landscape of sphingomyelinases
P Shanbhogue, YA Hannun
Lipid Signaling in Human Diseases, 19-47, 2020
192020
The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme
P Shanbhogue, RM Hoffmann, MV Airola, R Maini, DJ Hamelin, ...
Journal of Biological Chemistry 294 (18), 7488-7502, 2019
152019
Bovine antibody variants
CJ STRIETZEL, SAM LIGHTLE, HL CAMPOS, Y ZHU, G John FICI, ...
WO Patent WO2022109313A1, 2022
2022
Fragment-based de novo design targeting FABP5 and nSMase2
L Prentis, P Shanbhogue, Y Hannun, R Rizzo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Crystal structure and activation mechanism of human neutral sphingomyelinase 2
P Shanbhogue, M Airola, A Shamseddine, K Guja, R Maini, N Bartke, ...
The FASEB Journal 31, 781.8-781.8, 2017
2017
On the forces stabilizing supertertiary structure in multi‐domain proteins (770.2)
E Lemmon, P Shanbhogue, J McCann, M Bowen
The FASEB Journal 28, 770.2, 2014
2014
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