| Activity of epigenetic inhibitors against Plasmodium falciparum asexual and sexual blood stages LN Vanheer, H Zhang, G Lin, BFC Kafsack Antimicrobial agents and chemotherapy 64 (7), 10.1128/aac. 02523-19, 2020 | 35 | 2020 |
| Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors W Zhan, J Visone, T Ouellette, JC Harris, R Wang, H Zhang, PK Singh, ... Journal of medicinal chemistry 62 (13), 6137-6145, 2019 | 32 | 2019 |
| Development of a highly selective Plasmodium falciparum proteasome inhibitor with anti‐malaria activity in humanized mice G Lin, W Zhan, H Zhang, J Ginn, A Leung, YJ Liu, M Michino, A Toita, ... Angewandte Chemie International Edition, 2021 | 24 | 2021 |
| Total synthesis of (−)-gardmultimine A P Chen, H Yang, H Zhang, W Chen, Z Zhang, J Zhang, H Li, X Wang, ... Organic letters 22 (5), 2022-2025, 2020 | 23 | 2020 |
| Microbial proteasomes as drug targets H Zhang, G Lin PLoS Pathogens 17 (12), e1010058, 2021 | 21 | 2021 |
| Biomimetic Total Syntheses of (+)-Dihydrolyfoline and (−)-5-epi-Dihydrolyfoline R Mei, D Xu, H Hu, D Song, H Zhang, D Ma, X Xie, X She Organic letters 17 (9), 2230-2233, 2015 | 18 | 2015 |
| Palladium-promoted neutral 1, 4-Brook rearrangement/intramolecular allylic cyclization cascade reaction: A strategy for the construction of vinyl cyclobutanols H Zhang, S Ma, Z Yuan, P Chen, X Xie, X Wang, X She Organic letters 19 (13), 3478-3481, 2017 | 17 | 2017 |
| Total synthesis of conosilane A via a site-selective C–H functionalization strategy Z Yuan, X Hu, H Zhang, L Liu, P Chen, M He, X Xie, X Wang, X She Chemical Communications 54 (8), 912-915, 2018 | 13 | 2018 |
| Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome I Deni, BH Stokes, KE Ward, KJ Fairhurst, CFA Pasaje, T Yeo, S Akbar, ... Cell chemical biology 30 (5), 470-485. e6, 2023 | 11 | 2023 |
| Bioinspired total synthesis of (−)-gymnothelignan L P Chen, L Huo, H Li, L Liu, Z Yuan, H Zhang, S Feng, X Xie, X Wang, ... Organic Chemistry Frontiers 5 (7), 1124-1128, 2018 | 11 | 2018 |
| Design, synthesis, and optimization of macrocyclic peptides as species-selective antimalaria proteasome inhibitors H Zhang, J Ginn, W Zhan, YJ Liu, A Leung, A Toita, R Okamoto, TT Wong, ... Journal of medicinal chemistry 65 (13), 9350-9375, 2022 | 10 | 2022 |
| Rapid Construction of The 6/6/5 Tricyclic Framework via a tandem radical cyclization reaction and its application to the synthesis of 5-epi-7-deoxy-isoabietenin A H Zhang, S Ma, Z Xing, L Liu, B Fang, X Xie, X She Organic Chemistry Frontiers 4 (11), 2211-2215, 2017 | 10 | 2017 |
| Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome H Zhang, HC Hsu, SC Kahne, R Hara, W Zhan, X Jiang, K Burns-Huang, ... Journal of medicinal chemistry 64 (9), 6262-6272, 2021 | 9 | 2021 |
| Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance W Zhan, D Li, SB Subramanyaswamy, YJ Liu, C Yang, H Zhang, JC Harris, ... Cell chemical biology 30 (5), 457-469. e11, 2023 | 6 | 2023 |
| Concise Total Synthesis of Isospongian Diterpenoid (±)‐Polyrhaphin D Z Wang, Z Xing, L Liu, H Zhang, Z Zhong, DX Xie, X She ChemistrySelect 1 (10), 2225-2227, 2016 | 5 | 2016 |
| Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors HC Hsu, D Li, W Zhan, J Ye, YJ Liu, A Leung, J Qin, B Crespo, FJ Gamo, ... Nature Communications 14 (1), 8302, 2023 | 3 | 2023 |
| Discovery of highly selective inhibitors of the human constitutive proteasome β5c chymotryptic subunit W Zhan, D Li, P Saha, R Wang, H Zhang, AK Ajay, C Deban, G Sukenick, ... Journal of medicinal chemistry 66 (2), 1172-1185, 2023 | 3 | 2023 |
| Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum JM Bennett, KE Ward, RK Muir, S Kabeche, E Yoo, T Yeo, G Lam, ... ACS Infectious Diseases 9 (10), 2036-2047, 2023 | 2 | 2023 |
| Structure–Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II H Zhang, J Ginn, W Zhan, A Leung, YJ Liu, A Toita, R Okamoto, TT Wong, ... Journal of medicinal chemistry 66 (2), 1484-1508, 2023 | 2 | 2023 |
| High-Throughput/High Content Imaging Screen Identifies Novel Small Molecule Inhibitors and Immunoproteasomes as Therapeutic Targets for Chordoma AK Ajay, P Chu, P Patel, C Deban, C Roychowdhury, R Heda, A Halawi, ... Pharmaceutics 15 (4), 1274, 2023 | 1 | 2023 |
