Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen CJ Phiel, F Zhang, EY Huang, MG Guenther, MA Lazar, PS Klein Journal of Biological Chemistry 276 (39), 36734-36741, 2001 | 2121 | 2001 |
GSK-3α regulates production of Alzheimer's disease amyloid-β peptides CJ Phiel, CA Wilson, VMY Lee, PS Klein Nature 423 (6938), 435-439, 2003 | 1593 | 2003 |
Molecular targets of lithium action CJ Phiel, PS Klein Annual review of pharmacology and toxicology 41 (1), 789-813, 2001 | 661 | 2001 |
Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium: evidence for autoregulation of GSK-3 F Zhang, CJ Phiel, L Spece, N Gurvich, PS Klein Journal of Biological Chemistry 278 (35), 33067-33077, 2003 | 571 | 2003 |
Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci AP Popkie, LC Zeidner, AM Albrecht, A D'Ippolito, S Eckardt, DE Newsom, ... Journal of Biological Chemistry 285 (53), 41337-41347, 2010 | 101 | 2010 |
Glycogen synthase kinase-3α promotes fatty acid uptake and lipotoxic cardiomyopathy M Nakamura, T Liu, S Husain, P Zhai, JS Warren, CP Hsu, T Matsuda, ... Cell metabolism 29 (5), 1119-1134. e12, 2019 | 96 | 2019 |
Functions of B56-containing PP2As in major developmental and cancer signaling pathways J Yang, C Phiel Life sciences 87 (23-26), 659-666, 2010 | 73 | 2010 |
Targeted Disruption of Glycogen Synthase Kinase 3a (Gsk3a) in Mice Affects Sperm Motility Resulting in Male Infertility R Bhattacharjee, S Goswami, T Dudiki, AP Popkie, CJ Phiel, D Kline, ... Biology of reproduction 92 (3), 65, 1-12, 2015 | 69 | 2015 |
Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3. 3K27M mutation R Tatavosian, HN Duc, TN Huynh, D Fang, B Schmitt, X Shi, Y Deng, ... Nature communications 9 (1), 2080, 2018 | 67 | 2018 |
JLK isocoumarin inhibitors: Selective γ‐secretase inhibitors that do not interfere with notch pathway in vitro or in vivo A Petit, A Pasini, C Alves Da Costa, E Ayral, JF Hernandez, ... Journal of neuroscience research 74 (3), 370-377, 2003 | 58 | 2003 |
PP2A: B56ε is required for eye induction and eye field separation AM Rorick, W Mei, NL Liette, C Phiel, HM El-Hodiri, J Yang Developmental biology 302 (2), 477-493, 2007 | 56 | 2007 |
Differential binding of an SRF/NK-2/MEF2 transcription factor complex in normal versus neoplastic smooth muscle tissues CJ Phiel, V Gabbeta, LM Parsons, D Rothblat, RP Harvey, KM McHugh Journal of Biological Chemistry 276 (37), 34637-34650, 2001 | 49 | 2001 |
A noncatalytic domain of glycogen synthase kinase-3 (GSK-3) is essential for activity JL Buescher, CJ Phiel Journal of Biological Chemistry 285 (11), 7957-7963, 2010 | 47 | 2010 |
Gsk3β is required in the epithelium for palatal elevation in mice F He, AP Popkie, W Xiong, L Li, Y Wang, CJ Phiel, Y Chen Developmental Dynamics 239 (12), 3235-3246, 2010 | 46 | 2010 |
Identification of distinct molecular phenotypes in cultured gastrointestinal smooth muscle cells J Brittingham, C Phiel, WC Trzyna, V Gabbeta, KM McHugh Gastroenterology 115 (3), 605-617, 1998 | 43 | 1998 |
Cbx2 stably associates with mitotic chromosomes via a PRC2-or PRC1-independent mechanism and is needed for recruiting PRC1 complex to mitotic chromosomes CY Zhen, HN Duc, M Kokotovic, CJ Phiel, X Ren Molecular biology of the cell 25 (23), 3726-3739, 2014 | 41 | 2014 |
Isoform-specific requirement for GSK3α in sperm for male fertility R Bhattacharjee, S Goswami, S Dey, M Gangoda, C Brothag, A Eisa, ... Biology of reproduction 99 (2), 384-394, 2018 | 39 | 2018 |
Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus SG Gonzalez Malagon, AM Lopez Muñoz, D Doro, TG Bolger, E Poon, ... Nature Communications 9 (1), 1126, 2018 | 38 | 2018 |
The role for oxidative stress in aberrant DNA methylation in Alzheimer’s disease J L Fleming, C J Phiel, A Ewart Toland Current Alzheimer Research 9 (9), 1077-1096, 2012 | 37 | 2012 |
Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells KJ Faulds, JN Egelston, LJ Sedivy, MK Mitchell, S Garimella, H Kozlowski, ... Journal of Biological Chemistry 293 (27), 10731-10743, 2018 | 32 | 2018 |