Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family AJ Bridges, WA Denny, D Fry, A Kraker, RF Meyer, GW Rewcastle, ... US Patent 5,654,307, 1997 | 298 | 1997 |
Antiviral and antitumor agents from a New Zealand sponge, Mycale sp. 2. Structures and solution conformations of mycalamides A and B NB Perry, JW Blunt, MHG Munro, AM Thompson The Journal of Organic Chemistry 55 (1), 223-227, 1990 | 217 | 1990 |
Tyrosine Kinase Inhibitors. 10. Isomeric 4-[(3-Bromophenyl)amino]pyrido[d]- pyrimidines Are Potent ATP Binding Site Inhibitors of the Tyrosine Kinase Function of … GW Rewcastle, BD Palmer, AM Thompson, AJ Bridges, DR Cody, H Zhou, ... Journal of medicinal chemistry 39 (9), 1823-1835, 1996 | 208 | 1996 |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family AJ Bridges, WA Denny, D Fry, A Kraker, RF Meyer, GW Rewcastle, ... US Patent 6,265,410, 2001 | 190 | 2001 |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family AJ Bridges, WA Denny, D Fry, A Kraker, RF Meyer, GW Rewcastle, ... US Patent 6,455,534, 2002 | 177 | 2002 |
Substituted pyrido [3, 2-d] pyrimidines capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family AJ Bridges, WA Denny, D Fry, A Kraker, RF Meyer, GW Rewcastle, ... US Patent 6,084,095, 2000 | 174 | 2000 |
Tyrosine kinase inhibitors. 7. 7-Amino-4-(phenylamino)-and 7-amino-4-[(phenylmethyl) amino] pyrido [4, 3-d] pyrimidines: a new class of inhibitors of the tyrosine kinase … AM Thompson, AJ Bridges, DW Fry, AJ Kraker, WA Denny Journal of medicinal chemistry 38 (19), 3780-3788, 1995 | 174 | 1995 |
Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family AJ Bridges, WA Denny, D Fry, A Kraker, RF Meyer, GW Rewcastle, ... US Patent 5,679,683, 1997 | 168 | 1997 |
4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione Inhibitors of the Checkpoint Kinase Wee1. Structure−Activity Relationships for Chromophore Modification and … BD Palmer, AM Thompson, RJ Booth, EM Dobrusin, AJ Kraker, HH Lee, ... Journal of medicinal chemistry 49 (16), 4896-4911, 2006 | 129 | 2006 |
Synthesis and Structure− Activity Studies of Biphenyl Analogues of the Tuberculosis Drug (6 S)-2-Nitro-6-{[4-(trifluoromethoxy) benzyl] oxy}-6, 7-dihydro-5 H-imidazo [2, 1-b][1 … BD Palmer, AM Thompson, HS Sutherland, A Blaser, I Kmentova, ... Journal of medicinal chemistry 53 (1), 282-294, 2010 | 126 | 2010 |
Synthesis, reduction potentials, and antitubercular activity of ring A/B analogues of the bioreductive drug (6 S)-2-nitro-6-{[4-(trifluoromethoxy) benzyl] oxy}-6, 7-dihydro-5 H … AM Thompson, A Blaser, RF Anderson, SS Shinde, SG Franzblau, Z Ma, ... Journal of medicinal chemistry 52 (3), 637-645, 2009 | 124 | 2009 |
Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family AJ Bridges, WA Denny, D Fry, A Kraker, RF Meyer, GW Rewcastle, ... US Patent 6,596,726, 2003 | 122 | 2003 |
Synthesis and structure− activity relationships of antitubercular 2-nitroimidazooxazines bearing heterocyclic side chains HS Sutherland, A Blaser, I Kmentova, SG Franzblau, B Wan, Y Wang, ... Journal of medicinal chemistry 53 (2), 855-866, 2010 | 100 | 2010 |
Synthesis and Structure− Activity Relationships of Aza-and Diazabiphenyl Analogues of the Antitubercular Drug (6 S)-2-Nitro-6-{[4-(trifluoromethoxy) benzyl] oxy}-6, 7-dihydro-5 … I Kmentova, HS Sutherland, BD Palmer, A Blaser, SG Franzblau, B Wan, ... Journal of medicinal chemistry 53 (23), 8421-8439, 2010 | 96 | 2010 |
Tyrosine Kinase Inhibitors. 13. Structure−Activity Relationships for Soluble 7-Substituted 4-[(3-Bromophenyl)amino]pyrido[4,3-d]pyrimidines Designed as Inhibitors … AM Thompson, DK Murray, WL Elliott, DW Fry, JA Nelson, ... Journal of medicinal chemistry 40 (24), 3915-3925, 1997 | 91 | 1997 |
Tyrosine Kinase Inhibitors. 6. Structure− Activity Relationships among N-and 3-Substituted 2, 2 ‘-Diselenobis (1 H-indoles) for Inhibition of Protein Tyrosine Kinases and … HDH Showalter, AD Sercel, BM Leja, CD Wolfangel, LA Ambroso, ... Journal of medicinal chemistry 40 (4), 413-426, 1997 | 89 | 1997 |
From the Antarctic to the Antipodes; 45º of marine chemistry JW Blunt, MHG Munro, CN Battershill, BR Copp, JD McCombs, NB Perry, ... New Journal of Chemistry 14 (10), 761-775, 1990 | 87 | 1990 |
Tyrosine Kinase Inhibitors. 4. Structure-Activity Relationships among N-and 3-Substituted 2, 2'-Dithiobis (1H-indoles) for in vitro Inhibition of Receptor and Nonreceptor … BD Palmer, GW Rewcastle, AM Thompson, M Boyd, HDH Showalter, ... Journal of medicinal chemistry 38 (1), 58-67, 1995 | 85 | 1995 |
Tuberculosis drug discovery: challenges and new horizons GFS Fernandes, AM Thompson, D Castagnolo, WA Denny, ... Journal of Medicinal Chemistry 65 (11), 7489-7531, 2022 | 81 | 2022 |
Synthesis and Structure−Activity Relationships of 7-Substituted 3-(2,6-Dichlorophenyl)-1,6-naphthyridin-2(1H)-ones as Selective Inhibitors of pp60c-src AM Thompson, GW Rewcastle, SL Boushelle, BG Hartl, AJ Kraker, GH Lu, ... Journal of medicinal chemistry 43 (16), 3134-3147, 2000 | 80 | 2000 |