关注
Riley D. Metcalfe
Riley D. Metcalfe
Postdoctoral Fellow, NCI at Frederick
在 nih.gov 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structural understanding of interleukin 6 family cytokine signaling and targeted therapies: focus on interleukin 11
RD Metcalfe, TL Putoczki, MDW Griffin
Frontiers in immunology 11, 1424, 2020
832020
Emerging roles for IL-11 in inflammatory diseases
KY Fung, C Louis, RD Metcalfe, CC Kosasih, IP Wicks, MDW Griffin, ...
Cytokine 149, 155750, 2022
412022
The structure of the PA28–20S proteasome complex from Plasmodium falciparum and implications for proteostasis
SC Xie, RD Metcalfe, E Hanssen, T Yang, DL Gillett, AP Leis, CJ Morton, ...
Nature microbiology 4 (11), 1990-2000, 2019
362019
The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement
RD Metcalfe, K Aizel, CO Zlatic, PM Nguyen, CJ Morton, DSS Lio, ...
Journal of Biological Chemistry 295 (24), 8285-8301, 2020
352020
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
SC Xie, RD Metcalfe, E Dunn, CJ Morton, SC Huang, T Puhalovich, Y Du, ...
Science 376 (6597), 1074-1079, 2022
342022
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome
SC Xie, RD Metcalfe, H Mizutani, T Puhalovich, E Hanssen, CJ Morton, ...
Proceedings of the National Academy of Sciences 118 (39), e2107213118, 2021
222021
Functional and structural analysis of cytokine-selective IL6ST defects that cause recessive hyper-IgE syndrome
YH Chen, DB Zastrow, RD Metcalfe, L Gartner, F Krause, CJ Morton, ...
Journal of Allergy and Clinical Immunology 148 (2), 585-598, 2021
222021
Structural insights into the unique modes of relaxin-binding and tethered-agonist mediated activation of RXFP1 and RXFP2
A Sethi, S Bruell, T Ryan, F Yan, MH Tanipour, YF Mok, C Draper-Joyce, ...
Journal of Molecular Biology 433 (21), 167217, 2021
92021
Molecular basis of functional effects of phosphorylation of the C-terminal domain of the rabies virus P protein
J Zhan, E Watts, AM Brice, RD Metcalfe, AM Rozario, A Sethi, F Yan, ...
Journal of Virology 96 (9), e00111-22, 2022
72022
Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant
RD Metcalfe, E Hanssen, KY Fung, K Aizel, CC Kosasih, CO Zlatic, ...
Nature Communications 14 (1), 7543, 2023
5*2023
Unravelling the Carbohydrate‐Binding Preferences of the Carbohydrate‐Binding Modules of AMP‐Activated Protein Kinase
JI Mobbs, A Di Paolo, RD Metcalfe, E Selig, DI Stapleton, MDW Griffin, ...
Chembiochem 19 (3), 229-238, 2018
42018
Structure and regulation of full-length human leucine-rich repeat kinase 1
RD Metcalfe, JA Martinez Fiesco, L Bonet-Ponce, JH Kluss, MR Cookson, ...
Nature Communications 14 (1), 4797, 2023
22023
Cytokine Receptors and Their Ligands
KSCT Shing, WL Kan, TL Nero, TR Hercus, D Tvorogov, RD Metcalfe, ...
Encyclopedia of Cell Biology: Functional Aspects of Cell Biology-Part 1, 21-45, 2022
22022
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
SC Xie, Y Wang, CJ Morton, RD Metcalfe, C Dogovski, CFA Pasaje, ...
Nature communications 15 (1), 937, 2024
2024
A structural understanding of interleukin-11 signalling
RD Metcalfe
University of Melbourne, 2020
2020
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