Structural analysis of the nurse shark (new) antigen receptor (NAR): molecular convergence of NAR and unusual mammalian immunoglobulins KH Roux, AS Greenberg, L Greene, L Strelets, D Avila, EC McKinney, ... Proceedings of the National Academy of Sciences 95 (20), 11804-11809, 1998 | 305 | 1998 |
Cutting edge: DGYW/WRCH is a better predictor of mutability at G: C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step … IB Rogozin, M Diaz The Journal of Immunology 172 (6), 3382-3384, 2004 | 300 | 2004 |
The translesion DNA polymerase ζ plays a major role in Ig and bcl-6 somatic hypermutation H Zan, A Komori, Z Li, A Cerutti, A Schaffer, MF Flajnik, M Diaz, P Casali Immunity 14 (5), 643-653, 2001 | 253 | 2001 |
Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance L Verkoczy, M Diaz, TM Holl, YB Ouyang, H Bouton-Verville, SM Alam, ... Proceedings of the National Academy of Sciences 107 (1), 181-186, 2010 | 234 | 2010 |
Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks SS Brar, M Watson, M Diaz Journal of Biological Chemistry 279 (25), 26395-26401, 2004 | 202 | 2004 |
Mechanisms of environmental influence on human autoimmunity: a National Institute of Environmental Health Sciences expert panel workshop C Selmi, PSC Leung, DH Sherr, M Diaz, JF Nyland, M Monestier, ... Journal of autoimmunity 39 (4), 272-284, 2012 | 177 | 2012 |
Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase ζ M Diaz, LK Verkoczy, MF Flajnik, N R Klinman The Journal of Immunology 167 (1), 327-335, 2001 | 177 | 2001 |
Somatic immunoglobulin hypermutation M Diaz, P Casali Current opinion in immunology 14 (2), 235-240, 2002 | 160 | 2002 |
Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: Possible role in antigen-driven reactions in the … M Diaz, AS Greenberg, MF Flajnik Proceedings of the National Academy of Sciences 95 (24), 14343-14348, 1998 | 138 | 1998 |
Structural analysis, selection, and ontogeny of the shark new antigen receptor (IgNAR): identification of a new locus preferentially expressed in early development M Diaz, RL Stanfield, AS Greenberg, MF Flajnik Immunogenetics 54, 501-512, 2002 | 134 | 2002 |
Mutational pattern of the nurse shark antigen receptor gene (NAR) is similar to that of mammalian Ig genes and to spontaneous mutations in evolution: the translesion synthesis … M Diaz, J Velez, M Singh, J Cerny, MF Flajnik International immunology 11 (5), 825-833, 1999 | 132 | 1999 |
A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG LL Rumfelt, D Avila, M Diaz, S Bartl, EC McKinney, MF Flajnik Proceedings of the National Academy of Sciences 98 (4), 1775-1780, 2001 | 128 | 2001 |
Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH× VL knockin mice reveals multiple tolerance controls L Verkoczy, Y Chen, H Bouton-Verville, J Zhang, M Diaz, J Hutchinson, ... The Journal of Immunology 187 (7), 3785-3797, 2011 | 127 | 2011 |
Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice C Jiang, J Foley, N Clayton, G Kissling, M Jokinen, R Herbert, M Diaz The Journal of Immunology 178 (11), 7422-7431, 2007 | 114 | 2007 |
Evolution of somatic hypermutation and gene conversion in adaptive immunity M Diaz, ME Flcjnik Immunological reviews 162 (1), 13-24, 1998 | 106 | 1998 |
The immune system of cartilaginous fish MF Flajnik, LL Rumfelt Origin and evolution of the vertebrate immune system, 249-270, 2000 | 97 | 2000 |
Decreased Frequency and Highly Aberrant Spectrum of Ultraviolet-Induced Mutations in the hprt Gene of Mouse Fibroblasts Expressing Antisense RNA to DNA … M Diaz, NB Watson, G Turkington, LK Verkoczy, NR Klinman, ... Molecular cancer research 1 (11), 836-847, 2003 | 85 | 2003 |
A smad signaling network regulates islet cell proliferation Y El-Gohary, S Tulachan, J Wiersch, P Guo, C Welsh, K Prasadan, ... Diabetes 63 (1), 224-236, 2014 | 80 | 2014 |
Autoreactivity in HIV-1 broadly neutralizing antibodies: implications for their function and induction by vaccination L Verkoczy, M Diaz Current Opinion in HIV and AIDS 9 (3), 224-234, 2014 | 76 | 2014 |
Activation‐induced deaminase–deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis C Jiang, ML Zhao, RM Scearce, M Diaz Arthritis & Rheumatism 63 (4), 1086-1096, 2011 | 73 | 2011 |