The role of stromal cancer-associated fibroblasts in pancreatic cancer D Von Ahrens, TD Bhagat, D Nagrath, A Maitra, A Verma Journal of hematology & oncology 10, 1-8, 2017 | 400 | 2017 |
Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma W Wu, TD Bhagat, X Yang, JH Song, Y Cheng, R Agarwal, JM Abraham, ... Gastroenterology 144 (5), 956-966. e4, 2013 | 270 | 2013 |
Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations B Will, L Zhou, TO Vogler, S Ben-Neriah, C Schinke, R Tamari, Y Yu, ... Blood, The Journal of the American Society of Hematology 120 (10), 2076-2086, 2012 | 255 | 2012 |
Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells X Yang, JH Song, Y Cheng, W Wu, T Bhagat, Y Yu, JM Abraham, ... Gut 63 (6), 881-890, 2014 | 238 | 2014 |
Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS L Zhou, AN Nguyen, D Sohal, J Ying Ma, P Pahanish, K Gundabolu, ... Blood, The Journal of the American Society of Hematology 112 (8), 3434-3443, 2008 | 202 | 2008 |
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies MA Smith, GS Choudhary, A Pellagatti, K Choi, LC Bolanos, TD Bhagat, ... Nature cell biology 21 (5), 640-650, 2019 | 191 | 2019 |
IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells C Schinke, O Giricz, W Li, A Shastri, S Gordon, L Barreyro, T Bhagat, ... Blood, The Journal of the American Society of Hematology 125 (20), 3144-3152, 2015 | 181 | 2015 |
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma CJ Mariani, A Vasanthakumar, J Madzo, A Yesilkanal, T Bhagat, Y Yu, ... Cell reports 7 (5), 1343-1352, 2014 | 180 | 2014 |
Cytosine methylation dysregulation in neonates following intrauterine growth restriction F Einstein, RF Thompson, TD Bhagat, MJ Fazzari, A Verma, N Barzilai, ... PloS one 5 (1), e8887, 2010 | 163 | 2010 |
Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis H Alvarez, J Opalinska, L Zhou, D Sohal, MJ Fazzari, Y Yu, C Montagna, ... PLoS genetics 7 (3), e1001356, 2011 | 159 | 2011 |
miR-21 mediates hematopoietic suppression in MDS by activating TGF-β signaling TD Bhagat, L Zhou, L Sokol, R Kessel, G Caceres, K Gundabolu, ... Blood, The Journal of the American Society of Hematology 121 (15), 2875-2881, 2013 | 150 | 2013 |
Colony stimulating factor-1 receptor signaling networks inhibit mouse macrophage inflammatory responses by induction of microRNA-21 CI Caescu, X Guo, L Tesfa, TD Bhagat, A Verma, D Zheng, ER Stanley Blood, The Journal of the American Society of Hematology 125 (8), e1-e13, 2015 | 149 | 2015 |
Reduced SMAD7 leads to overactivation of TGF-β signaling in MDS that can be reversed by a specific inhibitor of TGF-β receptor I kinase L Zhou, C McMahon, T Bhagat, C Alencar, Y Yu, M Fazzari, D Sohal, ... Cancer research 71 (3), 955-963, 2011 | 147 | 2011 |
Myeloma is characterized by stage-specific alterations in DNA methylation that occur early during myelomagenesis CJ Heuck, J Mehta, T Bhagat, K Gundabolu, Y Yu, S Khan, G Chrysofakis, ... The Journal of Immunology 190 (6), 2966-2975, 2013 | 126 | 2013 |
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts TD Bhagat, D Von Ahrens, M Dawlaty, Y Zou, J Baddour, A Achreja, ... Elife 8, e50663, 2019 | 124 | 2019 |
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment B Will, TO Vogler, B Bartholdy, F Garrett-Bakelman, J Mayer, L Barreyro, ... Nature immunology 14 (5), 437, 2013 | 114 | 2013 |
High-dose ascorbic acid synergizes with anti-PD1 in a lymphoma mouse model RA Luchtel, T Bhagat, K Pradhan, WR Jacobs Jr, M Levine, A Verma, ... Proceedings of the National Academy of Sciences 117 (3), 1666-1677, 2020 | 106 | 2020 |
Efficacy of booster doses in augmenting waning immune responses to COVID-19 vaccine in patients with cancer LC Shapiro, A Thakkar, ST Campbell, SK Forest, K Pradhan, ... Cancer Cell 40 (1), 3-5, 2022 | 104 | 2022 |
Alterations in the ribosomal machinery in cancer and hematologic disorders N Shenoy, R Kessel, TD Bhagat, S Bhattacharyya, Y Yu, C Mcmahon, ... Journal of hematology & oncology 5, 1-9, 2012 | 101 | 2012 |
Upregulation of TET activity with ascorbic acid induces epigenetic modulation of lymphoma cells N Shenoy, T Bhagat, E Nieves, M Stenson, J Lawson, GS Choudhary, ... Blood cancer journal 7 (7), e587-e587, 2017 | 87 | 2017 |