Mediator and cohesin connect gene expression and chromatin architecture MH Kagey, JJ Newman, S Bilodeau, Y Zhan, DA Orlando, NL van Berkum, ... Nature 467 (7314), 430-435, 2010 | 2226 | 2010 |
Transcription factors activate genes through the phase-separation capacity of their activation domains A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ... Cell 175 (7), 1842-1855. e16, 2018 | 1402 | 2018 |
The Mediator complex: a central integrator of transcription BL Allen, DJ Taatjes Nature reviews Molecular cell biology 16 (3), 155-166, 2015 | 1011 | 2015 |
Activating RNAs associate with Mediator to enhance chromatin architecture and transcription F Lai, UA Orom, M Cesaroni, M Beringer, DJ Taatjes, GA Blobel, ... Nature 494 (7438), 497-501, 2013 | 942 | 2013 |
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates YE Guo, JC Manteiga, JE Henninger, BR Sabari, A Dall’Agnese, ... Nature 572 (7770), 543-548, 2019 | 530 | 2019 |
The Mediator complex and transcription regulation ZC Poss, CC Ebmeier, DJ Taatjes Critical reviews in biochemistry and molecular biology 48 (6), 575-608, 2013 | 420 | 2013 |
CDK8 is a positive regulator of transcriptional elongation within the serum response network AJ Donner, CC Ebmeier, DJ Taatjes, JM Espinosa Nature structural & molecular biology 17 (2), 194-201, 2010 | 416 | 2010 |
The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function MT Knuesel, KD Meyer, C Bernecky, DJ Taatjes Genes & development 23 (4), 439-451, 2009 | 400 | 2009 |
The human Mediator complex: a versatile, genome-wide regulator of transcription DJ Taatjes Trends in biochemical sciences 35 (6), 315-322, 2010 | 386 | 2010 |
Mediator kinase inhibition further activates super-enhancer-associated genes in AML HE Pelish, BB Liau, II Nitulescu, A Tangpeerachaikul, ZC Poss, ... Nature 526 (7572), 273-276, 2015 | 369 | 2015 |
Structure, function, and activator-induced conformations of the CRSP coactivator DJ Taatjes, AM Naar, F Andel III, E Nogales, R Tjian Science 295 (5557), 1058-1062, 2002 | 345 | 2002 |
Partitioning of cancer therapeutics in nuclear condensates IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ... Science 368 (6497), 1386-1392, 2020 | 339 | 2020 |
Structural visualization of key steps in human transcription initiation Y He, J Fang, DJ Taatjes, E Nogales Nature 495 (7442), 481-486, 2013 | 332 | 2013 |
CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response J Bancerek, ZC Poss, I Steinparzer, V Sedlyarov, T Pfaffenwimmer, ... Immunity 38 (2), 250-262, 2013 | 282 | 2013 |
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2 JC Schwartz, CC Ebmeier, ER Podell, J Heimiller, DJ Taatjes, TR Cech Genes & development 26 (24), 2690-2695, 2012 | 278 | 2012 |
The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator MT Knuesel, KD Meyer, AJ Donner, JM Espinosa, DJ Taatjes Molecular and cellular biology, 2009 | 260 | 2009 |
Structure and mechanism of the RNA polymerase II transcription machinery AC Schier, DJ Taatjes Genes & development 34 (7-8), 465-488, 2020 | 232 | 2020 |
An atlas of substrate specificities for the human serine/threonine kinome JL Johnson, TM Yaron, EM Huntsman, A Kerelsky, J Song, A Regev, ... Nature 613 (7945), 759-766, 2023 | 210 | 2023 |
Mediator condensates localize signaling factors to key cell identity genes AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ... Molecular cell 76 (5), 753-766. e6, 2019 | 209 | 2019 |
Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation AM Näär, DJ Taatjes, W Zhai, E Nogales, R Tjian Genes & development 16 (11), 1339-1344, 2002 | 203 | 2002 |