RNP-granule assembly via Ataxin-2 disordered domains is required for long-term memory and neurodegeneration B Bakthavachalu, J Huelsmeier, IP Sudhakaran, J Hillebrand, A Singh, ... Neuron 98 (4), 754-766. e4, 2018 | 114 | 2018 |
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy L Marrone, HCA Drexler, J Wang, P Tripathi, T Distler, P Heisterkamp, ... Acta neuropathologica 138, 67-84, 2019 | 108 | 2019 |
Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models EN Anderson, L Gochenaur, A Singh, R Grant, K Patel, S Watkins, JY Wu, ... Human molecular genetics 27 (8), 1366-1381, 2018 | 102 | 2018 |
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ... | 93 | 2019 |
WNK kinases sense molecular crowding and rescue cell volume via phase separation CR Boyd-Shiwarski, DJ Shiwarski, SE Griffiths, RT Beacham, L Norrell, ... Cell 185 (24), 4488-4506. e20, 2022 | 82 | 2022 |
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway YC Lin, MS Kumar, N Ramesh, EN Anderson, AT Nguyen, B Kim, ... Nature neuroscience 24 (8), 1077-1088, 2021 | 74 | 2021 |
Dual inhibition of GSK3β and CDK5 protects the cytoskeleton of neurons from neuroinflammatory-mediated degeneration in vitro and in vivo L Reinhardt, S Kordes, P Reinhardt, M Glatza, M Baumann, HCA Drexler, ... Stem cell reports 12 (3), 502-517, 2019 | 55 | 2019 |
Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesicles in vivo JA White, E Anderson, K Zimmerman, KH Zheng, R Rouhani, ... Human molecular genetics 24 (25), 7182-7195, 2015 | 51 | 2015 |
RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM N Ramesh, ENA Sukhleen Kour, D Rajasundaram, UB Pandey acta neuropathol commun 8 (138), 2020 | 40 | 2020 |
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology EN Anderson, AA Morera, S Kour, JD Cherry, N Ramesh, A Gleixner, ... Elife 10, e67587, 2021 | 36 | 2021 |
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility AM Gleixner, BM Verdone, CG Otte, EN Anderson, N Ramesh, ... Nature communications 13 (1), 3380, 2022 | 35 | 2022 |
Loss of function mutations in GEMIN5 cause a neurodevelopmental disorder S Kour, DS Rajan, TR Fortuna, EN Anderson, C Ward, Y Lee, S Lee, ... Nature communications 12 (1), 2558, 2021 | 31 | 2021 |
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6 A Migazzi, C Scaramuzzino, EN Anderson, D Tripathy, IH Hernández, ... Cell reports 35 (2), 2021 | 31 | 2021 |
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization I Casci, K Krishnamurthy, S Kour, V Tripathy, N Ramesh, EN Anderson, ... Nature Communications 10 (1), 5583, 2019 | 31 | 2019 |
Impairment of the mitochondrial one-carbon metabolism enzyme SHMT2 causes a novel brain and heart developmental syndrome À García-Cazorla, E Verdura, N Juliá-Palacios, EN Anderson, ... Acta neuropathologica 140, 971-975, 2020 | 27 | 2020 |
DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner TR Fortuna, S Kour, EN Anderson, C Ward, D Rajasundaram, ... Acta neuropathologica 142, 515-536, 2021 | 22 | 2021 |
RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3 N Ramesh, JR Gleixner, AM, Mann, S Kour, D Mawrie, EN Anderson, ... acta neuropathol commun 8 (177), DOI: 10.1186/s40478-020-01060-y, 2020 | 22 | 2020 |
The non-amyloidal component region of α-synuclein is important for α-synuclein transport within axons EN Anderson, D Hirpa, KH Zheng, R Banerjee, S Gunawardena Frontiers in Cellular Neuroscience 13, 540, 2020 | 21 | 2020 |
Axonal transport and neurodegenerative disease: vesicle-motor complex formation and their regulation EN Anderson, JA White, S Gunawardena Degenerative Neurological and Neuromuscular Disease, 29-47, 2014 | 15 | 2014 |
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice R Prakasam, A Bonadiman, R Andreotti, E Zuccaro, D Dalfovo, ... Nature Communications 14 (1), 603, 2023 | 14 | 2023 |