Modulation of myelopoiesis progenitors is an integral component of trained immunity I Mitroulis, K Ruppova, B Wang, LS Chen, M Grzybek, T Grinenko, ... Cell 172 (1), 147-161. e12, 2018 | 848 | 2018 |
CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease HJ Anders, TB Huber, B Isermann, M Schiffer Nature Reviews Nephrology 14 (6), 361-377, 2018 | 636 | 2018 |
Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis B Isermann, IA Vinnikov, T Madhusudhan, S Herzog, M Kashif, J Blautzik, ... Nature medicine 13 (11), 1349-1358, 2007 | 465 | 2007 |
Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy K Shahzad, F Bock, W Dong, H Wang, S Kopf, S Kohli, S Ranjan, J Wolter, ... Kidney international 87 (1), 74-84, 2015 | 420 | 2015 |
Thrombomodulin H Weiler, BH Isermann Journal of thrombosis and haemostasis 1 (7), 1515-1524, 2003 | 349 | 2003 |
Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kB MA Hofmann, S Schiekofer, B Isermann, M Kanitz, M Henkels, M Joswig, ... Diabetologia 42, 222-232, 1999 | 341 | 1999 |
The thrombomodulin–protein C system is essential for the maintenance of pregnancy B Isermann, R Sood, R Pawlinski, M Zogg, S Kalloway, JL Degen, ... Nature medicine 9 (3), 331-337, 2003 | 327 | 2003 |
Platelets contribute to postnatal occlusion of the ductus arteriosus K Echtler, K Stark, M Lorenz, S Kerstan, A Walch, L Jennen, M Rudelius, ... Nature medicine 16 (1), 75-82, 2010 | 269 | 2010 |
Protective regulation of the ACE2/ACE gene expression by estrogen in human atrial tissue from elderly men A Bukowska, L Spiller, C Wolke, U Lendeckel, S Weinert, J Hoffmann, ... Experimental Biology and Medicine 242 (14), 1412-1423, 2017 | 237 | 2017 |
Steroid-refractory GVHD: T-cell attack within a vulnerable endothelial system T Luft, S Dietrich, C Falk, M Conzelmann, M Hess, A Benner, F Neumann, ... Blood, The Journal of the American Society of Hematology 118 (6), 1685-1692, 2011 | 224 | 2011 |
Lipoprotein (a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac‐1 integrin SN Sotiriou, VV Orlova, N Al‐Fakhri, E Ihanus, M Economopoulou, ... The FASEB journal 20 (3), 559-561, 2006 | 203 | 2006 |
Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia BA Kerlin, SB Yan, BH Isermann, JT Brandt, R Sood, BR Basson, ... Blood 102 (9), 3085-3092, 2003 | 202 | 2003 |
Effect of α-lipoic acid on the progression of endothelial cell damage and albuminuria in patients with diabetes mellitus: an exploratory study M Morcos, V Borcea, B Isermann, S Gehrke, T Ehret, M Henkels, ... Diabetes research and clinical practice 52 (3), 175-183, 2001 | 191 | 2001 |
Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts S Kohli, S Ranjan, J Hoffmann, M Kashif, EA Daniel, MM Al-Dabet, F Bock, ... Blood, The Journal of the American Society of Hematology 128 (17), 2153-2164, 2016 | 176 | 2016 |
Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis B Isermann, SB Hendrickson, M Zogg, M Wing, M Cummiskey, ... The Journal of clinical investigation 108 (4), 537-546, 2001 | 175 | 2001 |
Characterization of a mouse model for thrombomodulin deficiency H Weiler, V Lindner, B Kerlin, BH Isermann, SB Hendrickson, BC Cooley, ... Arteriosclerosis, thrombosis, and vascular biology 21 (9), 1531-1537, 2001 | 172 | 2001 |
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy T Madhusudhan, H Wang, W Dong, S Ghosh, F Bock, VR Thangapandi, ... Nature communications 6 (1), 6496, 2015 | 164 | 2015 |
Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc F Bock, K Shahzad, H Wang, S Stoyanov, J Wolter, W Dong, PG Pelicci, ... Proceedings of the National Academy of Sciences 110 (2), 648-653, 2013 | 162 | 2013 |
Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin R Sood, L Sholl, B Isermann, M Zogg, SR Coughlin, H Weiler Blood, The Journal of the American Society of Hematology 112 (3), 585-591, 2008 | 159 | 2008 |
Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition S Nazir, I Gadi, MM Al-Dabet, A Elwakiel, S Kohli, S Ghosh, J Manoharan, ... Blood, The Journal of the American Society of Hematology 130 (24), 2664-2677, 2017 | 153 | 2017 |