A class switch control region at the 3′ end of the immunoglobulin heavy chain locus M Cogné, R Lansford, A Bottaro, J Zhang, J Gorman, F Young, HL Cheng, ... Cell 77 (5), 737-747, 1994 | 314 | 1994 |
CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. E Castigli, FW Alt, L Davidson, A Bottaro, E Mizoguchi, AK Bhan, RS Geha Proceedings of the National Academy of Sciences 91 (25), 12135-12139, 1994 | 312 | 1994 |
S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process. A Bottaro, R Lansford, L Xu, J Zhang, P Rothman, FW Alt The EMBO journal 13 (3), 665-674, 1994 | 245 | 1994 |
A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon. J Zhang, A Bottaro, S Li, V Stewart, FW Alt The EMBO journal 12 (9), 3529-3537, 1993 | 240 | 1993 |
Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus. J Chen, F Young, A Bottaro, V Stewart, RK Smith, FW Alt The EMBO journal 12 (12), 4635-4645, 1993 | 236 | 1993 |
Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice PR Borghesani, FW Alt, A Bottaro, L Davidson, S Aksoy, GA Rathbun, ... Proceedings of the National Academy of Sciences 97 (7), 3336-3341, 2000 | 214 | 2000 |
Class switching in B cells lacking 3′ immunoglobulin heavy chain enhancers JP Manis, N Van Der Stoep, M Tian, R Ferrini, L Davidson, A Bottaro, ... The Journal of experimental medicine 188 (8), 1421-1431, 1998 | 185 | 1998 |
Leukemia stem cells in a genetically defined murine model of blast-crisis CML SJ Neering, T Bushnell, S Sozer, J Ashton, RM Rossi, PY Wang, DR Bell, ... Blood, The Journal of the American Society of Hematology 110 (7), 2578-2585, 2007 | 170 | 2007 |
Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching. L Xu, B Gorham, SC Li, A Bottaro, FW Alt, P Rothman Proceedings of the National Academy of Sciences 90 (8), 3705-3709, 1993 | 143 | 1993 |
Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment … E Sakai, A Bottaro, L Davidson, BP Sleckman, FW Alt Proceedings of the National Academy of Sciences 96 (4), 1526-1531, 1999 | 133 | 1999 |
Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus KJ Seidl, JP Manis, A Bottaro, J Zhang, L Davidson, A Kisselgof, ... Proceedings of the National Academy of Sciences 96 (6), 3000-3005, 1999 | 116 | 1999 |
Expanded CD23+/CD21hi B cells in inflamed lymph nodes are associated with the onset of inflammatory-erosive arthritis in TNF-transgenic mice and are targets of anti-CD20 therapy J Li, I Kuzin, S Moshkani, ST Proulx, L Xing, D Skrombolas, R Dunn, ... The Journal of Immunology 184 (11), 6142-6150, 2010 | 98 | 2010 |
Tetracyclines inhibit activated B cell function II Kuzin, JE Snyder, GD Ugine, D Wu, S Lee, T Bushnell Jr, RA Insel, ... International immunology 13 (7), 921-931, 2001 | 97 | 2001 |
Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus. A Bottaro, F Young, J Chen, M Serwe, F Sablitzky, FW Alt International immunology 10 (6), 799-806, 1998 | 97 | 1998 |
Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells S Altuwaijri, KH Chuang, KP Lai, JJ Lai, HY Lin, FM Young, A Bottaro, ... Molecular Endocrinology 23 (4), 444-453, 2009 | 89 | 2009 |
Animal models of rheumatoid pain: experimental systems and insights BD Fischer, A Adeyemo, ME O’Leary, A Bottaro Arthritis research & therapy 19, 1-9, 2017 | 84 | 2017 |
Down‐regulation of CD20 on B cells upon CD40 activation J Anolik, RJ Looney, A Bottaro, I Sanz, F Young European journal of immunology 33 (9), 2398-2409, 2003 | 81 | 2003 |
Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development S Marr, H Morales, A Bottaro, M Cooper, M Flajnik, J Robert The Journal of Immunology 179 (10), 6783-6789, 2007 | 79 | 2007 |
The CD27–CD70 pathway and pathogenesis of autoimmune disease BK Han, NJ Olsen, A Bottaro Seminars in arthritis and rheumatism 45 (4), 496-501, 2016 | 78 | 2016 |
Efficacy of B cell depletion therapy for murine joint arthritis flare is associated with increased lymphatic flow J Li, Y Ju, EM Bouta, L Xing, RW Wood, I Kuzin, A Bottaro, CT Ritchlin, ... Arthritis & Rheumatism 65 (1), 130-138, 2013 | 71 | 2013 |