SOX9 is a potent activator of the chondrocyte-specific enhancer of the proα1 (II) collagen gene V Lefebvre, W Huang, VR Harley, PN Goodfellow, B De Crombrugghe Molecular and cellular biology, 1997 | 1314 | 1997 |
Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration W Huang, K Ma, J Zhang, M Qatanani, J Cuvillier, J Liu, B Dong, X Huang, ... Science 312 (5771), 233-236, 2006 | 780 | 2006 |
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization W Bi, W Huang, DJ Whitworth, JM Deng, Z Zhang, RR Behringer, ... Proceedings of the National Academy of Sciences 98 (12), 6698-6703, 2001 | 691 | 2001 |
Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response YD Wang, WD Chen, M Wang, D Yu, BM Forman, W Huang Hepatology 48 (5), 1632-1643, 2008 | 647 | 2008 |
Transcriptional mechanisms of chondrocyte differentiation B De Crombrugghe, V Lefebvre, RR Behringer, W Bi, S Murakami, ... Matrix Biology 19 (5), 389-394, 2000 | 589 | 2000 |
Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor F Yang, X Huang, T Yi, Y Yen, DD Moore, W Huang Cancer research 67 (3), 863-867, 2007 | 524 | 2007 |
The G‐Protein‐coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light‐chain enhancer of … YD Wang, WD Chen, D Yu, BM Forman, W Huang Hepatology 54 (4), 1421-1432, 2011 | 463 | 2011 |
Induction of bilirubin clearance by the constitutive androstane receptor (CAR) W Huang, J Zhang, SS Chua, M Qatanani, Y Han, R Granata, DD Moore Proceedings of the National Academy of Sciences 100 (7), 4156-4161, 2003 | 452 | 2003 |
FXR: a metabolic regulator and cell protector YD Wang, WD Chen, DD Moore, W Huang Cell research 18 (11), 1087-1095, 2008 | 403 | 2008 |
Bile acid nuclear receptor FXR and digestive system diseases L Ding, L Yang, Z Wang, W Huang Acta Pharmaceutica Sinica B 5 (2), 135-144, 2015 | 380 | 2015 |
Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR J Zhang, W Huang, SS Chua, P Wei, DD Moore Science 298 (5592), 422-424, 2002 | 368 | 2002 |
Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase a enhances SOX9's ability to transactivate aCol2a1 chondrocyte-specific enhancer W Huang, X Zhou, V Lefebvre, B De Crombrugghe Molecular and cellular biology, 2000 | 343 | 2000 |
Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB A Chow, W Zhou, L Liu, MY Fong, J Champer, D Van Haute, AR Chin, ... Scientific reports 4 (1), 5750, 2014 | 342 | 2014 |
Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor W Huang, J Zhang, M Washington, J Liu, JM Parant, G Lozano, DD Moore Molecular endocrinology 19 (6), 1646-1653, 2005 | 332 | 2005 |
The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones W Huang, U Chung, HM Kronenberg, B de Crombrugghe Proceedings of the National Academy of Sciences 98 (1), 160-165, 2001 | 312 | 2001 |
A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR W Huang, J Zhang, DD Moore The Journal of clinical investigation 113 (1), 137-143, 2004 | 304 | 2004 |
The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity J Zhang, W Huang, M Qatanani, RM Evans, DD Moore Journal of Biological Chemistry 279 (47), 49517-49522, 2004 | 292 | 2004 |
Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease B Dong, PK Saha, W Huang, W Chen, LA Abu-Elheiga, SJ Wakil, ... Proceedings of the National Academy of Sciences 106 (44), 18831-18836, 2009 | 289 | 2009 |
STAT3 activation-induced fatty acid oxidation in CD8+ T effector cells is critical for obesity-promoted breast tumor growth C Zhang, C Yue, A Herrmann, J Song, C Egelston, T Wang, Z Zhang, W Li, ... Cell metabolism 31 (1), 148-161. e5, 2020 | 247 | 2020 |
miR‐194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice Z Meng, X Fu, X Chen, S Zeng, Y Tian, R Jove, R Xu, W Huang Hepatology 52 (6), 2148-2157, 2010 | 242 | 2010 |