Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ... Nature genetics 46 (2), 136-143, 2014 | 573 | 2014 |
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ... Cell metabolism 16 (4), 435-448, 2012 | 490 | 2012 |
Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ... Cell reports 28 (7), 1717-1728. e6, 2019 | 323 | 2019 |
GATA6 haploinsufficiency causes pancreatic agenesis in humans HL Allen, SE Flanagan, C Shaw-Smith, E De Franco, I Akerman, ... Nature genetics 44 (1), 20-22, 2012 | 312 | 2012 |
Human pancreatic β cell lncRNAs control cell-specific regulatory networks I Akerman, Z Tu, A Beucher, DMY Rolando, C Sauty-Colace, M Benazra, ... Cell metabolism 25 (2), 400-411, 2017 | 230 | 2017 |
Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis I Garin, EL Edghill, I Akerman, O Rubio-Cabezas, I Rica, JM Locke, ... Proceedings of the National Academy of Sciences 107 (7), 3105-3110, 2010 | 221 | 2010 |
Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase DA Dart, KE Adams, I Akerman, ND Lakin Journal of Biological Chemistry 279 (16), 16433-16440, 2004 | 172 | 2004 |
Argonaute2 mediates compensatory expansion of the pancreatic β cell SG Tattikota, T Rathjen, SJ McAnulty, HH Wessels, I Akerman, ... Cell metabolism 19 (1), 122-134, 2014 | 168 | 2014 |
βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function L Arnes, I Akerman, DA Balderes, J Ferrer, L Sussel Genes & development 30 (5), 502-507, 2016 | 128 | 2016 |
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release D Nasteska, NHF Fine, FB Ashford, F Cuozzo, K Viloria, G Smith, A Dahir, ... Nature communications 12 (1), 674, 2021 | 65 | 2021 |
Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension CSJ Westgate, HF Botfield, Z Alimajstorovic, A Yiangou, M Walsh, G Smith, ... JCI insight 6 (10), 2021 | 56 | 2021 |
Metazoan DNA replication origins O Ganier, P Prorok, I Akerman, M Méchali Current opinion in cell biology 58, 134-141, 2019 | 52 | 2019 |
A predictable conserved DNA base composition signature defines human core DNA replication origins I Akerman, B Kasaai, A Bazarova, PB Sang, I Peiffer, M Artufel, R Derelle, ... Nature communications 11 (1), 4826, 2020 | 50 | 2020 |
ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage AL Medhurst, DO Warmerdam, I Akerman, EH Verwayen, R Kanaar, ... Journal of cell science 121 (23), 3933-3940, 2008 | 42 | 2008 |
GATA believe it: new essential regulators of pancreas development S Rodríguez-Seguí, I Akerman, J Ferrer The Journal of clinical investigation 122 (10), 3469-3471, 2012 | 30 | 2012 |
Hepatic nuclear factor 1α (HNF1α) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes β-cells to endoplasmic reticulum stress CL Kirkpatrick, A Wiederkehr, M Baquié, D Akhmedov, H Wang, ... Journal of Biological Chemistry 286 (37), 32300-32312, 2011 | 30 | 2011 |
Vitamin-D-binding protein contributes to the maintenance of α cell function and glucagon secretion K Viloria, D Nasteska, LJB Briant, S Heising, DP Larner, NHF Fine, ... Cell Reports 31 (11), 2020 | 24 | 2020 |
Neonatal Diabetes International Group I Garin, EL Edghill, I Akerman, O Rubio-Cabezas, I Rica, JM Locke, ... Johnstone K, Flanagan SE, Martinez R, Castano C, Patch AM, Fernandez-Rebollo …, 2010 | 20 | 2010 |
In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo F Fantuzzi, S Toivonen, AA Schiavo, H Chae, M Tariq, T Sawatani, ... Frontiers in Cell and Developmental Biology 10, 967765, 2022 | 17 | 2022 |
Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens L Schiffer, A Bossey, P Kempegowda, AE Taylor, I Akerman, ... European Journal of Endocrinology 184 (3), 353-363, 2021 | 13 | 2021 |