| Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain ii voltage sensor in the closed configuration Y Xiao, JP Bingham, W Zhu, E Moczydlowski, S Liang, TR Cummins Journal of Biological Chemistry 283 (40), 27300-27313, 2008 | 203 | 2008 |
| The tarantula toxins ProTx-II and huwentoxin-IV differentially interact with human Nav1. 7 voltage sensors to inhibit channel activation and inactivation Y Xiao, K Blumenthal, JO Jackson, S Liang, TR Cummins Molecular pharmacology 78 (6), 1124-1134, 2010 | 169 | 2010 |
| Voltage-gated sodium channel in grasshopper mice defends against bark scorpion toxin AH Rowe, Y Xiao, MP Rowe, TR Cummins, HH Zakon Science 342 (6157), 441-446, 2013 | 152 | 2013 |
| Stepwise differentiation of retinal ganglion cells from human pluripotent stem cells enables analysis of glaucomatous neurodegeneration SK Ohlemacher, A Sridhar, Y Xiao, AE Hochstetler, M Sarfarazi, ... Stem cells 34 (6), 1553-1562, 2016 | 138 | 2016 |
| CRMP2 protein SUMOylation modulates NaV1. 7 channel trafficking ET Dustrude, SM Wilson, W Ju, Y Xiao, R Khanna Journal of Biological Chemistry 288 (34), 24316-24331, 2013 | 108 | 2013 |
| Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana D Li, Y Xiao, W Hu, J Xie, F Bosmans, J Tytgat, S Liang FEBS letters 555 (3), 616-622, 2003 | 102 | 2003 |
| Inhibition of neuronal tetrodotoxin-sensitive Na+ channels by two spider toxins: hainantoxin-III and hainantoxin-IV Y Xiao, S Liang European journal of pharmacology 477 (1), 1-7, 2003 | 89 | 2003 |
| Jingzhaotoxin-I, a novel spider neurotoxin preferentially inhibiting cardiac sodium channel inactivation Y Xiao, J Tang, W Hu, J Xie, C Maertens, J Tytgat, S Liang Journal of Biological Chemistry 280 (13), 12069-12076, 2005 | 85 | 2005 |
| Structure-activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers D Li, Y Xiao, X Xu, X Xiong, S Lu, Z Liu, Q Zhu, M Wang, X Gu, S Liang Journal of Biological Chemistry 279 (36), 37734-37740, 2004 | 85 | 2004 |
| Jingzhaotoxin-III, a novel spider toxin inhibiting activation of voltage-gated sodium channel in rat cardiac myocytes Y Xiao, J Tang, Y Yang, M Wang, W Hu, J Xie, X Zeng, S Liang Journal of Biological Chemistry 279 (25), 26220-26226, 2004 | 78 | 2004 |
| Common molecular determinants of tarantula huwentoxin-IV inhibition of Na+ channel voltage sensors in domains II and IV Y Xiao, JO Jackson, S Liang, TR Cummins Journal of Biological Chemistry 286 (31), 27301-27310, 2011 | 72 | 2011 |
| Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation Z Pei, Y Xiao, J Meng, A Hudmon, TR Cummins Nature communications 7 (1), 12035, 2016 | 66 | 2016 |
| Isolation and characterization of hainantoxin-IV, a novel antagonist of tetrodotoxin-sensitive sodium channels from the Chinese bird spider Selenocosmia hainana Z Liu, J Dai, Z Chen, W Hu, Y Xiao, S Liang Cellular and Molecular Life Sciences CMLS 60, 972-978, 2003 | 61 | 2003 |
| Increased resurgent sodium currents in Nav1. 8 contribute to nociceptive sensory neuron hyperexcitability associated with peripheral neuropathies Y Xiao, C Barbosa, Z Pei, W Xie, JA Strong, JM Zhang, TR Cummins Journal of Neuroscience 39 (8), 1539-1550, 2019 | 56 | 2019 |
| Structural Basis for the Modulation of the Neuronal Voltage-Gated Sodium Channel NaV1.6 by Calmodulin VPR Chichili, Y Xiao, J Seetharaman, TR Cummins, J Sivaraman Scientific reports 3 (1), 2435, 2013 | 48 | 2013 |
| Gating-pore currents demonstrate selective and specific modulation of individual sodium channel voltage-sensors by biological toxins Y Xiao, K Blumenthal, TR Cummins Molecular pharmacology 86 (2), 159-167, 2014 | 47 | 2014 |
| Molecular basis of the tarantula toxin jingzhaotoxin‐III (β‐TRTX‐Cj1α) interacting with voltage sensors in sodium channel subtype Nav1. 5 M Rong, J Chen, H Tao, Y Wu, P Jiang, M Lu, H Su, Y Chi, T Cai, L Zhao, ... The FASEB Journal 25 (9), 3177-3185, 2011 | 47 | 2011 |
| Synthesis and characterization of huwentoxin-IV, a neurotoxin inhibiting central neuronal sodium channels Y Xiao, X Luo, F Kuang, M Deng, M Wang, X Zeng, S Liang Toxicon 51 (2), 230-239, 2008 | 47 | 2008 |
| Isolation and characterization of CvIV4: a pain inducing α-scorpion toxin AH Rowe, Y Xiao, J Scales, KD Linse, MP Rowe, TR Cummins, HH Zakon PloS one 6 (8), e23520, 2011 | 42 | 2011 |
| Purification and characterization of Hainantoxin-V, a tetrodotoxin-sensitive sodium channel inhibitor from the venom of the spider Selenocosmia hainana YC Xiao, SP Liang Toxicon 41 (6), 643-650, 2003 | 39 | 2003 |
