Serum microRNA screening and functional studies reveal miR-483-5p as a potential driver of fibrosis in systemic sclerosis E Chouri, NH Servaas, CPJ Bekker, AJ Affandi, M Cossu, MR Hillen, ... Journal of Autoimmunity 89, 162-170, 2018 | 80 | 2018 |
The long non-coding RNA NRIR drives IFN-response in monocytes: implication for systemic sclerosis B Mariotti, NH Servaas, M Rossato, N Tamassia, MA Cassatella, M Cossu, ... Frontiers in immunology 10, 100, 2019 | 72 | 2019 |
Plasmacytoid DCs from patients with Sjögren's syndrome are transcriptionally primed for enhanced pro-inflammatory cytokine production MR Hillen, A Pandit, SLM Blokland, SAY Hartgring, CPJ Bekker, ... Frontiers in immunology 10, 2096, 2019 | 64 | 2019 |
Longitudinal analysis of T-cell receptor repertoires reveals persistence of antigen-driven CD4+ and CD8+ T-cell clusters in systemic sclerosis NH Servaas, F Zaaraoui-Boutahar, CGK Wichers, A Ottria, E Chouri, ... Journal of autoimmunity 117, 102574, 2021 | 29 | 2021 |
GRaNIE and GRaNPA: inference and evaluation of enhancer‐mediated gene regulatory networks A Kamal, C Arnold, A Claringbould, R Moussa, NH Servaas, M Kholmatov, ... Molecular Systems Biology 19 (6), e11627, 2023 | 28 | 2023 |
Angiopoietin-2 promotes inflammatory activation in monocytes of systemic sclerosis patients T Carvalheiro, AP Lopes, M van der Kroef, B Malvar-Fernandez, ... International journal of molecular sciences 21 (24), 9544, 2020 | 16 | 2020 |
Characterization of long non-coding RNAs in systemic sclerosis monocytes: a potential role for PSMB8-AS1 in altered cytokine secretion NH Servaas, B Mariotti, M van der Kroef, CGK Wichers, A Pandit, ... International journal of molecular sciences 22 (9), 4365, 2021 | 12 | 2021 |
The role of innate immune cells in systemic sclerosis in the context of autologous hematopoietic stem cell transplantation NH Servaas, J Spierings, A Pandit, JM van Laar Clinical & Experimental Immunology 201 (1), 34-39, 2020 | 12 | 2020 |
GRaNIE and GRaNPA: Inference and evaluation of enhancer-mediated gene regulatory networks applied to study macrophages A Kamal, C Arnold, A Claringbould, R Moussa, NH Servaas, M Kholmatov, ... BioRxiv, 2021.12. 18.473290, 2021 | 11 | 2021 |
Nuclear receptor subfamily 4A signaling as a key disease pathway of CD1c+ dendritic cell dysregulation in systemic sclerosis NH Servaas, S Hiddingh, E Chouri, CGK Wichers, AJ Affandi, A Ottria, ... Arthritis & Rheumatology 75 (2), 279-292, 2023 | 8 | 2023 |
Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis G Mijnheer, NH Servaas, JY Leong, A Boltjes, E Spierings, P Chen, L Lai, ... Elife 12, e79016, 2023 | 7 | 2023 |
Escape from X inactivation is directly modulated by levels of Xist non-coding RNA A Hauth, J Panten, E Kneuss, C Picard, N Servant, I Rall, YA Pérez-Rico, ... bioRxiv, 2024 | 1 | 2024 |
Integration of genetic and epigenetic data pinpoints autoimmune specific remodelling of enhancer landscape in CD4+ T cells N Daga, NH Servaas, K Kisand, D Moonen, C Arnold, ... bioRxiv, 2024.01. 11.575022, 2024 | 1 | 2024 |
Transcriptome network analysis implicates CX3CR1-positive type 3 dendritic cells in non-infectious uveitis S Hiddingh, A Pandit, F Verhagen, R Rijken, NH Servaas, RCGK Wichers, ... Elife 12, e74913, 2023 | 1 | 2023 |
Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease S Lobato-Moreno, U Yildiz, A Claringbould, NH Servaas, EP Vlachou, ... bioRxiv, 2023.12. 26.573253, 2023 | | 2023 |
Circulating Monocytes in RA, SSc, and SLE Have Radically Altered and Unique Transcriptional & Epigenetic Profiles K Woolcock, N Servaas, M van der Kroef, S Delaney, J Cole, A Pandit, ... ARTHRITIS & RHEUMATOLOGY 75, 82-83, 2023 | | 2023 |
Unveiling the two faces of immune dysregulation in Systemic Sclerosis: A multi-omics approach NH Servaas Utrecht University, 2021 | | 2021 |
Transcriptome network analysis of human CD1c+ dendritic cells identifies an inflammatory cytokine-secreting subpopulation within the CD14+ DC3s that accumulates locally in type … S Hiddingh, A Pandit, FH Verhagen, R Rijken, NH Servaas, CGK Wichers, ... bioRxiv, 2021.11. 16.468816, 2021 | | 2021 |
COMPARTMENTALIZATION, PERSISTENCE AND CONSERVED SHARED MOTIFS OF DOMINANT (REGULATORY) T CELL CLONES IN AUTOIMMUNE INFLAMMATION G Mijnheer, N Servaas, L Lutter, JY Leong, E Spierings, P Chen, A Petrelli, ... Clinical and Experimental Rheumatology 39 (5), 1153-1154, 2021 | | 2021 |
Whole transcriptome-sequencing and network analysis of CD1c+ human dendritic cells identifies cytokine-secreting subsets linked to type I IFN-negative autoimmunity to the eye S Hiddingh, A Pandit, FH Verhagen, R Rijken, NH Servaas, CGK Wichers, ... bioRxiv, 2021 | | 2021 |