Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control SA Migueles, CM Osborne, C Royce, AA Compton, RP Joshi, KA Weeks, ... Immunity 29 (6), 1009-1021, 2008 | 670 | 2008 |
IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread AA Compton, T Bruel, F Porrot, A Mallet, M Sachse, M Euvrard, C Liang, ... Cell Host & Microbe 16 (6), 736-747, 2014 | 245 | 2014 |
Opposing activities of IFITM proteins in SARS-CoV-2 infection G Shi, AD Kenney, E Kudryashova, A Zani, L Zhang, KK Lai, ... The EMBO Journal, 2020 | 218 | 2020 |
Zika virus induces massive cytoplasmic vacuolization and paraptosis‐like death in infected cells B Monel*, AA Compton*, T Bruel, S Amraoui, J Burlaud‐Gaillard, N Roy, ... The EMBO Journal 36, 1653-1668, 2017 | 151 | 2017 |
The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict AA Compton, VM Hirsch, M Emerman Cell Host & Microbe 11 (1), 91-98, 2012 | 121 | 2012 |
More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins G Shi, O Schwartz, AA Compton Retrovirology 14 (1), 1-11, 2017 | 120 | 2017 |
IFITM3 requires an amphipathic helix for antiviral activity NM Chesarino, AA Compton, TM McMichael, AD Kenney, L Zhang, ... EMBO Reports, e201744100, 2017 | 118 | 2017 |
Convergence and divergence in the evolution of the APOBEC3G-Vif interaction reveal ancient origins of simian immunodeficiency viruses AA Compton, M Emerman PLOS Pathogens 9 (1), e1003135, 2013 | 108 | 2013 |
Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity AA Compton, N Roy, F Porrot, A Billet, N Casartelli, JS Yount, C Liang, ... EMBO Reports 17 (11), 1657-1671, 2016 | 100 | 2016 |
Lessons in self-defence: inhibition of virus entry by intrinsic immunity S Majdoul, AA Compton Nature Reviews Immunology 22 (6), 339-352, 2021 | 96 | 2021 |
Host gene evolution traces the evolutionary history of ancient primate lentiviruses AA Compton, HS Malik, M Emerman Philosophical Transactions of the Royal Society: B 368 (1626), 20120496, 2013 | 90 | 2013 |
mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3 G Shi, S Ozog, BE Torbett, AA Compton Proceedings of the National Academy of Sciences 115 (43), E10069-E10078, 2018 | 84 | 2018 |
Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state K Rahman, CA Coomer, S Majdoul, S Ding, S Padilla-Parra, AA Compton eLife 9, e58537, 2020 | 59 | 2020 |
They might be giants: does syncytium formation sink or spread HIV infection? AA Compton, O Schwartz PLOS Pathogens 13 (2), e1006099, 2017 | 54 | 2017 |
The hormonal herbicide, 2, 4-dichlorophenoxyacetic acid, inhibits Xenopus oocyte maturation by targeting translational and post-translational mechanisms AM LaChapelle, ML Ruygrok, ME Toomer, JJ Oost, ML Monnie, ... Reproductive Toxicology 23 (1), 20-31, 2007 | 51 | 2007 |
Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion CA Coomer, I Carlon-Andres, M Iliopoulou, ML Dustin, EB Compeer, ... PLOS Pathogens 16 (2), e1008359, 2020 | 39 | 2020 |
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2 G Shi, AI Chiramel, S Majdoul, KK Lai, T Dempsey, A Kenney, A Zani, ... Journal of Clinical Investigation 132 (24), e160766, 2022 | 34 | 2022 |
Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes S Ozog, ND Timberlake, K Hermann, O Garijo, KG Haworth, G Shi, ... Blood 134 (16), 1298-1311, 2019 | 32 | 2019 |
On the whereabouts of HIV-1 cellular entry and its fusion ports GM Jakobsdottir, M Iliopoulou, R Nolan, L Alvarez, AA Compton, ... Trends in Molecular Medicine 23 (10), 932-944, 2017 | 30 | 2017 |
IFITM3 reduces retroviral Envelope abundance and function and is counteracted by glycoGag YS Ahi, D Yimer, G Shi, S Majdoul, K Rahman, A Rein, AA Compton mBio 11 (1), e03088-19, 2020 | 29 | 2020 |