The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic E Kadosh, I Snir-Alkalay, A Venkatachalam, S May, A Lasry, E Elyada, ... Nature 586 (7827), 133-138, 2020 | 261 | 2020 |
Small molecules co-targeting CKIα and the transcriptional kinases CDK7/9 control AML in preclinical models W Minzel, A Venkatachalam, A Fink, E Hung, G Brachya, I Burstain, ... Cell 175 (1), 171-185. e25, 2018 | 128 | 2018 |
Atypical profiles and modulations of heme-enzymes catalyzed outcomes by low amounts of diverse additives suggest diffusible radicals' obligatory involvement in such redox reactions KM Manoj, A Parashar, A Venkatachalam, S Goyal, S Moharana, ... Biochimie, 2016 | 62 | 2016 |
Functioning of Microsomal Cytochrome P450s: Murburn Concept Explains the Metabolism of Xenobiotics in Hepatocytes KM Manoj, A Parashar, SK Gade, A Venkatachalam Frontiers in pharmacology 7, 161, 2016 | 58 | 2016 |
Electron transfer amongst flavo-and hemo-proteins: diffusible species effect the relay processes, not protein–protein binding KM Manoj, SK Gade, A Venkatachalam, DA Gideon RSC advances 6 (29), 24121-24129, 2016 | 53 | 2016 |
Cyanide does more to inhibit heme enzymes, than merely serving as an active-site ligand A Parashar, A Venkatachalam, DA Gideon, KM Manoj Biochemical and biophysical research communications 455 (3-4), 190-193, 2014 | 51 | 2014 |
Functioning of drug-metabolizing microsomal cytochrome P450s: In silico probing of proteins suggests that the distal heme ‘active site’ pocket plays a relatively … A Venkatachalam, A Parashar, KM Manoj In Silico Pharmacology 4, 1-38, 2016 | 44 | 2016 |
Metabolism of xenobiotics by cytochrome P450: novel insights into the thermodynamics, kinetics and roles of redox proteins and diffusible reactive species KM Manoj, A Venkatachalam, A Parashar Drug metabolism reviews 48, 41-42, 2016 | 22 | 2016 |
Putative homeostatic role of cancer driver mutations A Venkatachalam, E Pikarsky, Y Ben-Neriah Trends in Cell Biology 32 (1), 8-17, 2022 | 6 | 2022 |
Bioavailable dual-protein degraders of CK1α and transcriptional kinase CDK9 as potential therapeutics for hematological malignancies L Fung, AH Chourasia, E Torres, I Lam, P Erdman, D Hecht, R Sullivan, ... Blood 134, 4643, 2019 | 3 | 2019 |
Tissue-Predisposition to Cancer Driver Mutations L Peters, A Venkatachalam, Y Ben-Neriah Cells 13 (2), 106, 2024 | 2 | 2024 |
Pyrazole compounds and uses thereof D Li, I Snir-Alkalay, J Vacca, Y Ben-Neriah, A Venkatachalam US Patent 11,072,599, 2021 | 1 | 2021 |