| Advances and challenges of HDAC inhibitors in cancer therapeutics JJ McClure, X Li, CJ Chou Advances in cancer research 138, 183-211, 2018 | 313 | 2018 |
| Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases CJ Chou, D Herman, JM Gottesfeld Journal of Biological Chemistry 283 (51), 35402-35409, 2008 | 241 | 2008 |
| Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model M Rai, E Soragni, CJ Chou, G Barnes, S Jones, JR Rusche, JM Gottesfeld, ... PloS one 5 (1), e8825, 2010 | 176 | 2010 |
| A novel class of small molecule inhibitors of HDAC6 ES Inks, BJ Josey, SR Jesinkey, CJ Chou ACS chemical biology 7 (2), 331-339, 2012 | 144 | 2012 |
| Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing C Xu, E Soragni, CJ Chou, D Herman, HL Plasterer, JR Rusche, ... Chemistry & biology 16 (9), 980-989, 2009 | 144 | 2009 |
| Short laminin peptide for improved neural stem cell growth X Li, X Liu, B Josey, CJ Chou, Y Tan, N Zhang, X Wen Stem cells translational medicine 3 (5), 662-670, 2014 | 125 | 2014 |
| Structure–activity relationship study of vitamin K derivatives yields highly potent neuroprotective agents BJ Josey, ES Inks, X Wen, CJ Chou Journal of medicinal chemistry 56 (3), 1007-1022, 2013 | 100 | 2013 |
| Discovery of novel pazopanib-based HDAC and VEGFR dual inhibitors targeting cancer epigenetics and angiogenesis simultaneously J Zang, X Liang, Y Huang, Y Jia, X Li, W Xu, CJ Chou, Y Zhang Journal of Medicinal Chemistry 61 (12), 5304-5322, 2018 | 97 | 2018 |
| Design, synthesis, and antitumor evaluation of novel histone deacetylase inhibitors equipped with a phenylsulfonylfuroxan module as a nitric oxide donor W Duan, J Li, ES Inks, CJ Chou, Y Jia, X Chu, X Li, W Xu, Y Zhang Journal of medicinal chemistry 58 (10), 4325-4338, 2015 | 93 | 2015 |
| Development of allosteric hydrazide-containing class I histone deacetylase inhibitors for use in acute myeloid leukemia JJ McClure, C Zhang, ES Inks, YK Peterson, J Li, CJ Chou Journal of medicinal chemistry 59 (21), 9942-9959, 2016 | 90 | 2016 |
| Discovery of the First N-Hydroxycinnamamide-Based Histone Deacetylase 1/3 Dual Inhibitors with Potent Oral Antitumor Activity X Li, ES Inks, X Li, J Hou, CJ Chou, J Zhang, Y Jiang, Y Zhang, W Xu Journal of medicinal chemistry 57 (8), 3324-3341, 2014 | 88 | 2014 |
| Extracellular vesicle-mediated long-range communication in stressed retinal pigment epithelial cell monolayers N Shah, M Ishii, C Brandon, Z Ablonczy, J Cai, Y Liu, CJ Chou, B Rohrer Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (8 …, 2018 | 78 | 2018 |
| Class I HDAC inhibitors display different antitumor mechanism in leukemia and prostatic cancer cells depending on their p53 status X Li, YK Peterson, ES Inks, RA Himes, J Li, Y Zhang, X Kong, CJ Chou Journal of medicinal chemistry 61 (6), 2589-2603, 2018 | 77 | 2018 |
| Silver-catalyzed direct thiolation of quinones by activation of aryl disulfides to synthesize quinonyl aryl thioethers C Zhang, J McClure, CJ Chou The Journal of organic chemistry 80 (10), 4919-4927, 2015 | 75 | 2015 |
| Discovery of novel janus kinase (JAK) and histone deacetylase (HDAC) dual inhibitors for the treatment of hematological malignancies X Liang, J Zang, X Li, S Tang, M Huang, M Geng, CJ Chou, C Li, Y Cao, ... Journal of medicinal chemistry 62 (8), 3898-3923, 2019 | 72 | 2019 |
| HDAC1 localizes to the mitochondria of cardiac myocytes and contributes to early cardiac reperfusion injury DJ Herr, M Baarine, SE Aune, X Li, LE Ball, JJ Lemasters, CC Beeson, ... Journal of molecular and cellular cardiology 114, 309-319, 2018 | 63 | 2018 |
| HDACs regulate miR-133a expression in pressure overload–induced cardiac fibrosis L Renaud, LG Harris, SK Mani, H Kasiganesan, JC Chou, CF Baicu, ... Circulation: Heart Failure 8 (6), 1094-1104, 2015 | 61 | 2015 |
| Development of N-Hydroxycinnamamide-Based Histone Deacetylase Inhibitors with an Indole-Containing Cap Group Y Zhang, P Yang, CJ Chou, C Liu, X Wang, W Xu ACS medicinal chemistry letters 4 (2), 235-238, 2013 | 59 | 2013 |
| Functional studies of the Mycobacterium tuberculosis iron-dependent regulator CJ Chou, G Wisedchaisri, RR Monfeli, DM Oram, RK Holmes, WGJ Hol, ... Journal of Biological Chemistry 279 (51), 53554-53561, 2004 | 58 | 2004 |
| Comparison of the deacylase and deacetylase activity of zinc-dependent HDACs JJ McClure, ES Inks, C Zhang, YK Peterson, J Li, K Chundru, B Lee, ... ACS chemical biology 12 (6), 1644-1655, 2017 | 54 | 2017 |
J. M. GottesfeldThe Scripps Research Institute在 scripps.edu 的电子邮件经过验证
