Development of a highly selective c-Src kinase inhibitor KR Brandvold, ME Steffey, CC Fox, MB Soellner ACS chemical biology 7 (8), 1393-1398, 2012 | 160 | 2012 |
The chemical biology of molecular chaperones—implications for modulation of proteostasis KR Brandvold, RI Morimoto Journal of molecular biology 427 (18), 2931-2947, 2015 | 119 | 2015 |
Conformation-selective analogues of dasatinib reveal insight into kinase inhibitor binding and selectivity FE Kwarcinski, KR Brandvold, S Phadke, OM Beleh, TK Johnson, ... ACS chemical biology 11 (5), 1296-1304, 2016 | 76 | 2016 |
Development of a chimeric c-Src kinase and HDAC inhibitor KS Ko, ME Steffey, KR Brandvold, MB Soellner ACS medicinal chemistry letters 4 (8), 779-783, 2013 | 56 | 2013 |
A continuous fluorescence assay for simple quantification of bile salt hydrolase activity in the gut microbiome KR Brandvold, JM Weaver, C Whidbey, AT Wright Scientific Reports 9 (1), 1359, 2019 | 28 | 2019 |
UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer RA Gilani, S Phadke, LW Bao, EJ Lachacz, ML Dziubinski, KR Brandvold, ... Clinical Cancer Research 22 (20), 5087-5096, 2016 | 28 | 2016 |
Exquisitely specific bisubstrate inhibitors of c-Src kinase KR Brandvold, SM Santos, ME Breen, EJ Lachacz, ME Steffey, ... ACS chemical biology 10 (6), 1387-1391, 2015 | 28 | 2015 |
Activity‐Based Protein Profiling of Bile Salt Hydrolysis in the Human Gut Microbiome with Beta‐Lactam or Acrylamide‐Based Probes KR Brandvold, CJ Miller, RF Volk, BJ Killinger, C Whidbey, AT Wright ChemBioChem 22 (8), 1448-1455, 2021 | 14 | 2021 |
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure WL Garcia, CJ Miller, GX Lomas, KA Gaither, KJ Tyrrell, JN Smith, ... Chemical research in toxicology 35 (4), 585-596, 2022 | 13 | 2022 |
Ai-accelerated design of targeted covalent inhibitors for SARS-CoV-2 RP Joshi, KJ Schultz, JW Wilson, A Kruel, RA Varikoti, CJ Kombala, ... Journal of Chemical Information and Modeling 63 (5), 1438-1453, 2023 | 11 | 2023 |
Simple analysis of primary and secondary bile salt hydrolysis in mouse and human gut microbiome samples by using fluorogenic substrates A Sveistyte, T Gibbins, KJ Tyrrell, CJ Miller, MH Foley, AE Plymale, ... ChemBioChem 21 (24), 3539-3543, 2020 | 9 | 2020 |
Bile salt hydrolase probe and method of making and using the same AT Wright, KR Brandvold, S Ramos-Hunter US Patent 11,155,573, 2021 | 8 | 2021 |
Who is metabolizing what? Discovering novel biomolecules in the microbiome and the organisms who make them SP Couvillion, N Agrawal, SM Colby, KR Brandvold, TO Metz Frontiers in Cellular and Infection Microbiology 10, 388, 2020 | 7 | 2020 |
Profiling rhythmicity of bile salt hydrolase activity in the gut lumen with a rapid fluorescence assay CJ Kombala, N Agrawal, A Sveistyte, IN Karatsoreos, HPA Van Dongen, ... Organic & Biomolecular Chemistry 21 (19), 4028-4038, 2023 | 5 | 2023 |
Chemoproteomic analyses by activity‐based protein profiling BJ Killinger, KR Brandvold, SJ Ramos‐Hunter, AT Wright Mass spectrometry‐based chemical proteomics, 67-99, 2019 | 3 | 2019 |
Integrated data-driven and experimental approaches to accelerate lead optimization targeting SARS-CoV-2 main protease RA Varikoti, KJ Schultz, CJ Kombala, A Kruel, KR Brandvold, M Zhou, ... Journal of Computer-Aided Molecular Design 37 (8), 339-355, 2023 | 2 | 2023 |
Bile salt hydrolase profiling by fluorogenic probes in the human gut microbiome A Sveistyte, CJ Miller, KR Brandvold, AT Wright Methods in Enzymology 664, 243-265, 2022 | 2 | 2022 |
Retraction: UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer RA Gilani, S Phadke, LW Bao, EJ Lachacz, ML Dziubinski, KR Brandvold, ... Clinical Cancer Research 26 (7), 1777-1777, 2020 | 1 | 2020 |
Lactobacillus acidophilus disrupts collaborative multispecies bile acid metabolism S Dautel, N Khan, KR Brandvold, CJ Brislawn, J Hutchison, KK Weitz, ... bioRxiv, 296020, 2018 | 1 | 2018 |
Improving kinase inhibitor selectivity through exploring adjacent non-conserved pockets KR Brandvold, MB Soellner ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011 | 1 | 2011 |